Results 131 to 140 of about 61,152 (267)

Efficacy and Safety of Automated Insulin Delivery in People With Type 2 Diabetes: A Systematic Review and Meta‐Analysis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Studies evaluating automated insulin delivery (AID) in type 2 diabetes are limited in number and often conducted in small cohorts. We aimed to summarize efficacy and safety data through a systematic review and meta‐analysis. Materials and Methods We searched MEDLINE, PubMed, Web of Science, and CENTRAL databases and performed hand ...
Sergio Di Molfetta, Ludovico Di Gioia, Irene Caruso, Mariangela Caporusso, Sebastio Perrini, Annalisa Natalicchio, Luigi Laviola, Francesco Giorgino   +7 more
wiley   +1 more source

Glucose-dependent insulinotropic peptide (GIP) suppresses androgen biosynthesis in PCOS mouse models and cellular systems

Gynecological Endocrinology
Objective To assess the potential therapeutic effects of glucose-dependent insulinotropic peptide (GIP) on hyperandrogenism.Methods Polycystic ovary syndrome (PCOS) mouse models induced by dehydroepiandrosterone (DHEA) were established to evaluate the ...
Mengru Pan, Yifan Qian, Linlin Jiang, Chunwei Cao, lin li   +4 more
doaj   +1 more source

Diagnosis and management of equine metabolic syndrome

Equine Veterinary Education, EarlyView.
Summary Equine metabolic syndrome (EMS) is a prevalent endocrine disorder that increases the risk of hyperinsulinaemia‐associated laminitis (HAL), the most common and clinically significant form of laminitis. The central pathological feature of EMS is insulin dysregulation (ID), which encompasses basal or postprandial hyperinsulinaemia and tissue ...
F. R. Bertin
wiley   +1 more source

Identification of a mitochondrial receptor complex required for recognition and membrane insertion of precursor proteins [PDF]

, 1990
Griffiths, Gareth, Horstmann, Heinz, Kiebler, Michael, Neupert, Walter, Pfaller, Rupert, Pfanner, Nikolaus, Söllner, Thomas   +6 more
core   +1 more source

Recent advances in incretin biology and therapeutics: From glucose‐dependent insulinotropic polypeptide reappraisal to next‐generation agonists

Journal of Diabetes Investigation, EarlyView.
Future directions in incretin research: Three major directions currently shape therapeutic innovation in incretin research: multi‐receptor agonism, oral drug development, and mechanistic reappraisal of glucose‐dependent insulinotropic polypeptide (GIP) physiology.
Sodai Kubota, Yutaka Seino, Daisuke Yabe
wiley   +1 more source

NDR2 regulates non-small cell lung cancer cell migration under starvation by supporting autophagosome biogenesis through LC3 and ATG9A regulation

Cell Death Discovery
Non-small cell lung cancer (NSCLC) is characterized by the deregulation of the Hippo kinase NDR2 and high basal autophagic activity. NDR2 promotes autophagy-driven tumor growth in some cancers, but evidence in lung cancer is lacking.
Tiphaine Biojout, Emmanuel Bergot, Jasmine Taylor, Dimitri Leite Ferreira, Nathalie Colloc’h, Marc Riffet, Nicolas Elie, Maelle Guyot, Céline Bazille, Jérôme Levallet, Guénaëlle Levallet   +10 more
doaj   +1 more source

Nutrition Strategies for Next‐Generation Incretin Therapies: A Systematic Scoping Review of the Current Evidence

Obesity Reviews, EarlyView.
ABSTRACT Next‐generation incretin therapies, including semaglutide and tirzepatide, have transformed obesity and Type 2 diabetes management. However, evidence‐based nutritional strategies to support safe and effective use of these agents remain limited.
Marie Spreckley, Cara F. Ruggiero, Adrian Brown   +2 more
wiley   +1 more source

Multidisciplinary Therapy to Target Obesity and Its Complications in Adult Population: A Narrative Review

Obesity Reviews, EarlyView.
ABSTRACT Obesity as a chronic and multifactorial disease requires a multidisciplinary team acting together in a holistic multitarget intervention. Multidisciplinary therapy targeting obesity and its complications includes physical exercise, nutritional, and behavior counseling.
Ana Raimunda Dâmaso, Flávia Campos Corgosinho, Deborah Cristina Landi Masquio, Nayra Figueiredo, Fabiana Kattah, Cintia Cercato, Lian Tock, Raquel Munhoz da Silveira Campos   +7 more
wiley   +1 more source

Effects of Glucagon‐Like Peptide‐1 Receptor Agonists (Mono and Combination Therapy) on Energy Expenditure: A Scoping Review

Obesity Reviews, EarlyView.
ABSTRACT Introduction Weight loss results in reduced energy expenditure (EE) due to body composition alterations (e.g., fat‐free mass and fat mass losses) and mass‐independent adaptations in EE (e.g., hormones). Glucagon‐like peptide‐1 receptor agonists (GLP‐1RA) are indicated for obesity management; however, their effects on EE remain unclear ...
Flavio T. Vieira, ZhiDi Deng, Manfred J. Muller, Giovanna G. L. Bergamasco, Sarah Cawsey, Melania Manco, Steven B. Heymsfield, Carla M. Prado, Andrea M. Haqq   +8 more
wiley   +1 more source

Brukertilpasset gips

, 2019
Denne tekniske rapporten tar for seg utvikling og konstruksjon av en løsning som er designet for å erstatte dagens gipsprosess ved håndleddsbrudd. Løsningen innebærer å 3D-skanne en hånd og 3D-printe en brukertilpasset gipsskinne, og baserer seg på en tidligere hovedoppgave fra 2017. Denne prosessen skulle automatiseres ved å bruke dagens 3D-teknologi,
Sjåstad, Denis, Alvestad, Vegard Justsen André, Nedrelid, Oscar Hatlo   +2 more
openaire   +1 more source