Results 201 to 210 of about 72,161 (311)

Recognition of precursor proteins by the mitochondrial protein import apparatus [PDF]

, 1993
Becker, Karin, Gustafson, J. A., Neupert, Walter, Wirtz, Karel W. A.   +3 more
core   +1 more source

The incretin system in healthy humans: The role of GIP and GLP-1.

Metabolism: Clinical and Experimental, 2019
J. Holst
semanticscholar   +1 more source

Preclinical Modeling and Simulation to Explore the Tissue/Plasma Exposure and Pharmacodynamic Effect of Vildagliptin in Diabetes Treatment

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Vildagliptin (VDG) is a dipeptidyl‐peptidase‐4 (DPP‐4) inhibitor used for type 2 diabetes (T2DM) treatment. Viewing to improve VDG treatment, a population pharmacokinetic (popPK) model was built to describe drug plasma, free liver and muscle concentrations determined by microdialysis in healthy and diabetic animals following 50 mg/kg i.v ...
Bruna Bernar Dias, Laura Ben Olivo, Bibiana Verlindo de Araújo   +2 more
wiley   +1 more source

Prevalence of use and interest in using glucagon-like peptide-1 receptor agonists for weight loss: a population study in Great Britain. [PDF]

BMC Med
Jackson SE, Brown J, Llewellyn C, Mytton O, Shahab L.   +4 more
europepmc   +1 more source

Effects of combined GIP and GLP-1 infusion on energy intake, appetite and energy expenditure in overweight/obese individuals: a randomised, crossover study

Diabetologia, 2019
N. Bergmann, A. Lund, L. Gasbjerg, E. Meessen, Maria M. Andersen, Sigrid Bergmann, B. Hartmann, J. Holst, L. Jessen, M. Christensen, T. Vilsbøll, F. Knop   +11 more
semanticscholar   +1 more source

An Original PEG‐Functionalized PS Resin Enables Synthesis of Difficult Peptides: Application to Tirzepatide

ChemistrySelect, Volume 11, Issue 6, 12 February 2026.
The Seplife Fmoc‐RinkAmide‐PS‐PEG resin, a PEG‐grafted PS resin with optimized composition enables improved swelling and higher loading for SPPS. This resin delivers efficient couplings and high crude purities, supporting reliable synthesis of long and complex peptides.
Ashish Kumar, Peter K. Kabwe, Mahama Alhassan, Wei Hou, Chaoyang Wang, Cheng Zhang, Yanjun Li, Xiaokang Kou, Simona Serban, Alessandra Basso, Anamika Sharma, Beatriz G. De La Torre, Fernando Albericio   +12 more
wiley   +1 more source

Decreased risk of post-thyroidectomy hypocalcemia with history of GLP-1RA use. [PDF]

J Endocr Soc
Ayo-Ajibola O, Jung T, Razura DE, Gallagher TJ, Lin ME, Angell TE, Kwon DI.   +6 more
europepmc   +1 more source

Who Wins the Battle Against Obesity? A Network Meta‐Analysis Comparing Tirzepatide and Semaglutide

Journal of Diabetes, Volume 18, Issue 2, February 2026.
Network meta‐analysis comparing the effects of tirzepatide, semaglutide, and placebo on body weight reduction and glycemic outcomes in adults with overweight or obesity. ABSTRACT Introduction Pharmacological therapies are recommended for individuals with obesity.
Julia C. Bernardi, Deivyd V. S. Cavalcante, Ramon Huntermann, Maria E. Molinari, Luana Z. Zanon, Jacinthe Khater, Victor A. Gomez, Caroline O. Fischer‐Bacca   +7 more
wiley   +1 more source

GLP-2 and GIP acutely increase superior mesenteric artery blood flow in male rats, and the effect is independent of nitric oxide and vasoactive intestinal peptide. [PDF]

Physiol Rep
Galsgaard KD, Hartmann B, Rosenkilde MM, Holst JJ, Gasbjerg LS, Sørensen CM.   +5 more
europepmc   +1 more source

Delphi Consensus on the Use of Fenofibrate as Systemic Therapy for the Prevention of Diabetic Retinopathy Progression

Journal of Diabetes, Volume 18, Issue 2, February 2026.
Nineteen international endocrinologists support fenofibrate use to prevent diabetic retinopathy progression and emphasize the need for coordinated care pathways and early intervention to improve diabetic retinopathy management globally. ABSTRACT Background Diabetic retinopathy remains a leading cause of preventable blindness worldwide, yet screening ...
Richard C. O'Brien, Khalifa Abdallah, Xuehong Dong, Mohamed Hassanein, Qiuhe Ji, Sakir Ozgur Keskek, Patricio Lopez‐Jaramillo, Roopa Mehta, Hussein Raef, Kevin Tan   +9 more
wiley   +1 more source