Drug Design, Development and Therapy, 2022 Lijing Wang College of Life Sciences and Technology, China Pharmaceutical University, Nanjing, Jiangsu, People’s Republic of ChinaCorrespondence: Lijing Wang, College of Life Science and Technology, China Pharmaceutical University, 639 Longmian ...
Wang L
doaj
Detailed optical and near-infrared polarimetry, spectroscopy and broadband photometry of the afterglow of GRB 091018: Polarisation evolution [PDF]
, 2012 [Abridged] A number of phenomena have been observed in GRB afterglows that defy explanation by simple versions of the standard fireball model, leading to a variety of new models.
A. de Ugarte Postigo +119 more
core +6 more sources
Mechanisms of action and therapeutic applications of GLP-1 and dual GIP/GLP-1 receptor agonists
Frontiers in EndocrinologyGlucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are two incretins that bind to their respective receptors and activate the downstream signaling in various tissues and organs.
Qiyuan Keith Liu
semanticscholar +1 more source
GIP-derived GIP receptor antagonists – a review of their role in GIP receptor pharmacology [PDF]
PeptidesSurprisingly, agonists, as well as antagonists of the glucose-dependent insulinotropic polypeptide receptor (GIPR), are currently being used or investigated as treatment options for type 2 diabetes and obesity - and both, when combined with glucagon-like peptide 1 receptor (GLP-1R) agonism, enhance GLP-1-induced glycemia and weight loss further.
Rosenkilde, Mette Marie +3 more
openaire +3 more sources
European Stroke JournalIntroduction: Mounting evidence suggests that glucagon-like-peptide-1 receptor-agonists (GLP-1 RAs) attenuate cardiovascular-risk in type-2 diabetes (T2DM). Tirzepatide is the first-in-class, dual glucose-dependent-insulinotropic-polypeptide GIP/GLP-1 RA
Maria-Ioanna Stefanou +13 more
semanticscholar +1 more source
Early steps in mitochondrial protein import [PDF]
, 1990 The process of insertion of precursor proteins into mitochondrial membranes was investigated using a hybrid protein (pSc1-c) that contains dual targeting information and, at the same time, membrane insertion activity.
Neupert, Walter +2 more
core +1 more source
Explicit Decomposition Theorem for special Schubert varieties
, 2019 We give a short and self-contained proof of the Decomposition Theorem for the non-small resolution of a Special Schubert variety. We also provide an explicit description of the perverse cohomology sheaves.
Franco, Davide
core +1 more source
Biogenesis of mitochondrial porin [PDF]
, 1990 We review here the present knowledge about the pathway of import and assembly of porin into mitochondria and compare it to those of other mitochondrial proteins.
A. Grossmann +74 more
core +1 more source
The evolution of the therapeutic concept ‘GIP receptor antagonism’
Frontiers in EndocrinologyGlucose-dependent insulinotropic polypeptide (GIP) is an intestinal hormone that potentiates glucose-induced insulin secretion in the postprandial state. GIP exerts a broad range of other physiological actions e.g.
Frederikke Koefoed-Hansen +9 more
doaj +1 more source
The Dietary Intervention of Transgenic Low-Gliadin Wheat Bread in Patients with Non-Celiac Gluten Sensitivity (NCGS) Showed No Differences with Gluten Free Diet (GFD) but Provides Better Gut Microbiota Profile [PDF]
, 2018 The study evaluated the symptoms, acceptance, and digestibility of bread made from transgenic low-gliadin wheat, in comparison with gluten free bread, in Non-coeliac gluten sensitivity (NCGS) patients, considering clinical/sensory parameters and gut ...
Comino Montilla, Isabel María +10 more
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