Expression and Prognostic Role of Glia Maturation Factor-γ in Gliomas [PDF]
Frontiers in Molecular Neuroscience, 2022 BackgroundGlia maturation factor-γ (GMFG) regulates actin cytoskeletal organization and promotes the invasion of cancer cells. However, its expression pattern and molecular function in gliomas have not been clearly defined.MethodsIn this study, public ...
Junhui Liu +7 more
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Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy [PDF]
Redox Biology, 2022 Diabetic retinopathy (DR) is one of the leading causes of blindness in the world, and timely prevention and treatment are very important. Previously, we found that a neurodegenerative factor, Glia maturation factor-β (GMFB), was upregulated in the ...
Wang Juan, Jiao Li, Guo-Tong Xu
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Bioinformatics and survival analysis of glia maturation factor-γ in pan-cancers [PDF]
BMC Cancer, 2021 Background Glia maturation factor-γ (GMFG) is reported to inhibit the actin nucleation through binding to the actin-related protein-2/3 complex (Arp2/3).
Aihua Lan +4 more
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Glia Maturation Factor and Mitochondrial Uncoupling Proteins 2 and 4 Expression in the Temporal Cortex of Alzheimer’s Disease Brain [PDF]
Frontiers in Aging Neuroscience, 2017 Alzheimer’s disease (AD) is characterized by the presence of neuropathological lesions containing amyloid plaques (APs) and neurofibrillary tangles (NFTs).
Sudhanshu Raikwar +2 more
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Overexpression of glia maturation factor reinstates susceptibility to myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in glia maturation factor deficient mice [PDF]
Neurobiology of Disease, 2010 Glia maturation factor (GMF), a primarily CNS localized protein was discovered and characterized in our laboratory. We previously demonstrated that GMF is the upstream regulator for excessive production and release of proinflammatory cytokines/chemokines
Asgar Zaheer +2 more
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Augmented expression of glia maturation factor in Alzheimer's disease [PDF]
Neuroscience, 2011 We have previously demonstrated that glia maturation factor (GMF), a brain-specific protein, isolated, sequenced, and cloned in our laboratory, is a prominent mediator of inflammation in the CNS leading to the death of neurons. In the present study, we demonstrate, for the first time, a significant upregulation of the GMF protein in various regions of ...
Asgar Zaheer
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Expression of glia maturation factor in neuropathological lesions of Alzheimer's disease [PDF]
Neuropathology and Applied Neurobiology, 2012 R. Thangavel, D. Stolmeier, X. Yang, P. Anantharam and A. Zaheer (2012) Neuropathology and Applied Neurobiology38, 572–581Expression of glia maturation factor in neuropathological lesions of Alzheimer's diseaseAims: The pathology of Alzheimer's disease (AD) is characterized by the presence of amyloid plaques (APs), neurofibrillary tangles (NFTs ...
Thangavel R +4 more
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Glia maturation factor beta deficiency protects against diabetic osteoporosis by suppressing osteoclast hyperactivity [PDF]
Experimental and Molecular Medicine, 2023 Excessive osteoclast activation, which depends on dramatic changes in actin dynamics, causes osteoporosis (OP). The molecular mechanism of osteoclast activation in OP related to type 1 diabetes (T1D) remains unclear. Glia maturation factor beta (GMFB) is
Si Shi +16 more
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Glia Maturation Factor Beta as a Novel Biomarker and Therapeutic Target for Hepatocellular Carcinoma [PDF]
Frontiers in Oncology, 2021 Hepatocellular carcinoma (HCC) is one of the most common types of cancer. The novel sensitive biomarkers and therapeutic targets are urgently needed for the early diagnosis of HCC and improvement of clinical outcomes. Glia maturation factor-β (GMFB) is a
Wan Sun +23 more
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Glia maturation factor-γ is required for initiation and maintenance of hematopoietic stem and progenitor cells [PDF]
Stem Cell Research & Therapy, 2023 Background In vertebrates, hematopoietic stem and progenitor cells (HSPCs) emerge from hemogenic endothelium in the floor of the dorsal aorta and subsequently migrate to secondary niches where they expand and differentiate into committed lineages.
Honghu Li +9 more
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