Results 31 to 40 of about 22,955 (239)
Open Medicine, 2023 Patients with non-small-cell lung cancer (NSCLC) have a low survival rate. Long non-coding RNA (LncRNA) LANCL1 antisense RNA 1 (LANCL1-AS1) was indicated to be downregulated in NSCLC; however, its detailed function in NSCLC is unanswered.
Pan Hui, Peng Jing, Qiao Xiaoni, Gao Han
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Actin-dependent astrocytic infiltration is a key step for axon defasciculation during remodeling
Cell Reports, 2023 Summary: Astrocytes are essential for synapse formation, maturation, and plasticity; however, their function during developmental neuronal remodeling is largely unknown.
Neta Marmor-Kollet +6 more
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Purification and characterization of glia maturation factor beta: a growth regulator for neurons and glia. [PDF]
Proceedings of the National Academy of Sciences, 1989 A protein has been isolated from bovine brains by using a modification of the procedure used to purify glia maturation factor. The method consists of ammonium sulfate precipitation, chromatography with DEAE-Sephacel, Sephadex G-75, and hydroxylapatite columns, passage through a heparin-Sepharose column, and finally fractionation by reverse-phase HPLC ...
R, Lim, J F, Miller, A, Zaheer
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Frontiers in Molecular Neuroscience, 2023 Adaptive neuroplasticity is a pivotal mechanism for healthy brain development and maintenance, as well as its restoration in disease- and age-associated decline. Management of mental disorders such as attention deficit hyperactivity disorder (ADHD) needs
Alhasan Abdulghani +4 more
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Cells, 2021 The transcription factor nuclear factor kappa B (NF-κB) is highly expressed in almost all types of cells. NF-κB is involved in many complex biological processes, in particular in immunity. The activation of the NF-κB signaling pathways is also associated
Marina Mostafizar +5 more
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Genomics, Proteomics & Bioinformatics, 2003 Abstract It is standard practice, whenever a researcher finds a new gene, to search databases for genes that have a similar sequence. It is not standard practice, whenever a researcher finds a new gene, to search for genes that have similar expression (co-expression).
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Cells, 2020 Retinal neurons, particularly retinal ganglion cells (RGCs), are susceptible to the degenerative damage caused by different inherited conditions and environmental insults, leading to irreversible vision loss and, ultimately, blindness.
Xandra Pereiro +3 more
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Reprogramming Human Adult Fibroblasts into GABAergic Interneurons
Cells, 2021 Direct reprogramming is an appealing strategy to generate neurons from a somatic cell by forced expression of transcription factors. The generated neurons can be used for both cell replacement strategies and disease modelling.
Andreas Bruzelius +5 more
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Frontiers in Psychiatry, 2019 Schizophrenia is a severe and disabling psychiatric disorder with a complex and multifactorial etiology. The lack of consensus regarding the multifaceted dysfunction of this ailment has increased the need to explore new research lines.
Daniela Rodrigues-Amorim +13 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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