Glia Maturation Factor β as a Novel Independent Prognostic Biomarker and Potential Therapeutic Target of Kidney Renal Clear Cell Carcinoma [PDF]
Frontiers in Oncology, 2022 Kidney renal clear cell carcinoma (KIRC) has the highest mortality rate and potential for invasion among renal cancers. The diagnosis and treatment of KIRC are becoming challenging because of its diverse pathogenic mechanisms.
Tong Zhu +22 more
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The Actin-Disassembly Protein Glia Maturation Factor γ Enhances Actin Remodeling and B Cell Antigen Receptor Signaling at the Immune Synapse [PDF]
Frontiers in Cell and Developmental Biology, 2021 Signaling by the B cell antigen receptor (BCR) initiates actin remodeling. The assembly of branched actin networks that are nucleated by the Arp2/3 complex exert outward force on the plasma membrane, allowing B cells to form membrane protrusions that can
Nikola Deretic +4 more
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Glia Maturation Factor Beta: A Novel Neuro-Impairment Prediction Factor in Toxoplasmosis. [PDF]
Iran J Public HealthBackground: Toxoplasma gondii, a neurotropic protozoan, infects up one to third of the world population. The parasite can invade a wide variety of nucleated cells but preferably glial cells. Glia maturation factor β (GMFβ), a 17KD protein expressed at high levels in the central nervous system is predominantly related to neurodegenerative diseases such ...
Matini M, Amini R, Foroughi-Parvar F.
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Glia maturation factor-β: a potential therapeutic target in neurodegeneration and neuroinflammation. [PDF]
Neuropsychiatr Dis Treat, 2018 Glia maturation factor-β (GMFB) is considered to be a growth and differentiation factor for both glia and neurons. GMFB has been found to be upregulated in several neuroinflammation and neurodegeneration conditions. It may function by mediating apoptosis and by modulating the expression of superoxide dismutase, granulocyte-macrophage colony-stimulating
Fan J +5 more
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Glia maturation factor expression in hippocampus of human Alzheimer's disease. [PDF]
Neurochem Res, 2013 Alzheimer's disease (AD) is characterized by the presence of neuropathological lesions containing amyloid plaques (APs) and neurofibrillary tangles (NFTs) associated with neuroinflammation and neuronal degeneration. Hippocampus is one of the earliest and severely damaged areas in AD brain.
Stolmeier D +5 more
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Glia Maturation Factor in the Pathogenesis of Alzheimer's disease. [PDF]
Open Access J Neurol Neurosurg, 2019 Ramaswamy SB +12 more
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First description of enhanced expression of glia maturation factor-beta in experimental toxoplasmic encephalitis [PDF]
Journal of International Medical Research, 2017 Güngör çağdaş DİNÇEL
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Parkinson’s Disease Dementia Patients: Expression of Glia Maturation Factor in the Brain [PDF]
International Journal of Molecular SciencesSudhanshu Raikwar +2 more
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Deletion of gmfA induces keratocyte‐like migration in Dictyostelium
FEBS Open Bio, 2022 Glia maturation factor (GMF) has been established as an inactivating factor of the actin‐related protein 2/3 (Arp2/3) complex, which regulates actin assembly. Regulation of actin assembly and reorganization is crucial for various cellular events, such as
Koushiro Fujimoto +3 more
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ID4 Is Required for Normal Ependymal Cell Development
Frontiers in Neuroscience, 2021 Ependymal cells are radial glia-derived multiciliated cells lining the lateral ventricles of the brain and spinal cord. Correct development and coordinated cilia beating is essential for proper cerebrospinal fluid (CSF) flow and neurogenesis modulation ...
Brenda Rocamonde +4 more
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