Results 21 to 30 of about 265,026 (309)
CXCL16/CXCR6 axis drives microglia/macrophages phenotype in physiological conditions and plays a crucial role in glioma [PDF]
, 2018 Microglia are patrolling cells that sense changes in the brain microenvironment and respond acquiring distinct phenotypes that can be either beneficial or detrimental for brain homeostasis.
Antonangeli, Fabrizio +6 more
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Neurosurgery Clinics of North America, 2021 Only a small fraction of the tumor cell population, glioma-initiating cells (GICs) help glioblastoma propagate, invade, evade immune recognition, repair DNA in response to radiation more efficiently, remodel the microenvironment for optimal growth, and actively pump out chemotherapies.
Muftuoglu, Yagmur, Pajonk, Frank
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Cell Transplantation, 2021 FBXO17 is a newly studied F-box protein associated with high-grade glioma. However, its exact role in glioma remains unclear. In the present study, we aimed to investigate the role of FBXO17 in glioma both in vitro and in vivo and explore the underlying ...
Ning Wang, Qian Song, Hai Yu, Gang Bao
doaj +1 more source
Temozolomide and Resistant Glioma Cells
Journal of Neurosurgery, 2008 J ...
Kyritsis, A. P. +3 more
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Electrophysiology of glioma: a Rho GTPase-activating protein reduces tumor growth and spares neuron structure and function [PDF]
, 2016 Background. Glioblastomas are the most aggressive type of brain tumor. A successful treatment should aim at halting tumor growth and protecting neuronal cells to prevent functional deficits and cognitive deterioration.
Ammassari-Teule, M +11 more
core +1 more source
SIPA1 boosts migration and proliferation, and blocks apoptosis of glioma by activating the phosphorylation of the FAK signaling pathway [PDF]
Journal of Medical Biochemistry, 2022 Background: We aimed to analyze the regulatory effects of SIPA1 (signal-induced proliferation-associated protein 1) on glioma progression and the dominant signaling pathway.
Du Yuan +4 more
doaj +1 more source
Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy [PDF]
, 2011 Background: Even in the presence of oxygen, malignant cells often highly depend on glycolysis for energy generation, a phenomenon known as the Warburg effect.
Maurer, Gabriele D. +8 more
core +1 more source
MTSS1 is epigenetically regulated in glioma cells and inhibits glioma cell motility
Translational Oncology, 2017 Epigenetic silencing by DNA methylation in brain tumors has been reported for many genes, however, their function on pathogenesis needs to be evaluated. We investigated the MTSS1 gene, identified as hypermethylated by differential methylation hybridization (DMH).
Daniel Luxen +13 more
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Drug Design, Development and Therapy, 2022 Peizhang Wu,1,2 Jun Guo,2 Hongwei Yang,2 Debin Yuan,2 Chaoxiang Wang,2 Zhong Wang1 1Department of Neurosurgery, The First Affiliated Hospital of Soochow University, Suzhou, 215006, People’s Republic of China; 2Department of Neurosurgery, Yancheng First ...
Wu P +5 more
doaj
EphB4 is overexpressed in gliomas and promotes the growth of glioma cells
Tumor Biology, 2012 Glioma is one of the most common solid tumors, and the molecular mechanism for this disease is poorly understood. EphB4 tyrosine kinase receptor has been involved in various physiologic and pathologic processes, and the role of EphB4 in tumorigenesis has recently attracted much interest. However, its function in glioma remains largely unknown.
Tao, Chen +5 more
openaire +2 more sources