Results 91 to 100 of about 1,835 (174)

Opioid-Mediated Astrocyte–Neuron Signaling in the Nucleus Accumbens

Cells, 2019
Major hallmarks of astrocyte physiology are the elevation of intracellular calcium in response to neurotransmitters and the release of neuroactive substances (gliotransmitters) that modulate neuronal activity.
Michelle Corkrum, Patrick E. Rothwell, Mark J. Thomas, Paulo Kofuji, Alfonso Araque   +4 more
doaj   +1 more source

Inhibition of connexin43 hemichannels impairs spatial short-term memory without affecting spatial working memory

Frontiers in Cellular Neuroscience, 2016
Astrocytes are active players in higher brain function as they can release gliotransmitters, which are essential for synaptic plasticity. Various mechanisms have been proposed for gliotransmission, including vesicular mechanisms as well as non-vesicular ...
Laura Walrave, Mathieu Vinken, Giulia Albertini, Dimitri De Bundel, Luc Leybaert, Ilse Julia Smolders   +5 more
doaj   +1 more source

Gliotransmission at Tripartite Synapses

, 2020
Signal exchange between astrocytes and neurons at tripartite synapses has emerged as a crucial element of neural circuits in the brain. The position of astrocyte processes facing synapses provides the proper structural and functional conditions for ...
Perea, Gertrudis, González-Arias, Candela   +1 more
core   +1 more source

The effect of gliotransmission and stress on behavioral and molecular markers of cocaine-induced synaptic plasticity

, 2012
A great deal of research has focused on elucidating what makes cocaine so addictive. While cocaine\u27s actions appear simple—dopamine transporter blockade that elicits increases in extracellular dopamine—the downstream signaling pathways that are ...
Ecke, Laurel Elizabeth
core  

The role of astroglia in the antidepressant action of deep brain stimulation

Frontiers in Cellular Neuroscience, 2016
Adeline eEtiévant, Adeline eEtiévant, Guillaume eLucas, Ouria eDkhissi-Benyahya, Nasser eHaddjeri   +4 more
doaj   +1 more source

Endogenous nonneuronal modulators of synaptic transmission control cortical slow oscillations in vivo

, 2009
Gliotransmission, the release of molecules from astrocytes, regulates neuronal excitability and synaptic transmission in situ. Whether this process affects neuronal network activity in vivo is not known.
M. Terunuma, Halassa, Michael M, F. Succol, H. Takano, Takano, Hajime, Moss, Stephen J, Frank, Marcos, Succol, Francesca, M. M. Halassa, T. Fellin, S. J. Moss, M. Frank, Fellin, Tommaso, Haydon, Philip G, P. G. Haydon, Terunuma, Miho   +15 more
core   +1 more source

A lactate-dependent shift of glycolysis mediates synaptic and cognitive processes in male mice

Nature Communications
Astrocytes control brain activity via both metabolic processes and gliotransmission, but the physiological links between these functions are scantly known. Here we show that endogenous activation of astrocyte type-1 cannabinoid (CB1) receptors determines
Ignacio Fernández-Moncada, Gianluca Lavanco, Unai B. Fundazuri, Nasrin Bollmohr, Sarah Mountadem, Tommaso Dalla Tor, Pauline Hachaguer, Francisca Julio-Kalajzic, Doriane Gisquet, Roman Serrat, Luigi Bellocchio, Astrid Cannich, Bérénice Fortunato-Marsol, Yusuke Nasu, Robert E. Campbell, Filippo Drago, Carla Cannizzaro, Guillaume Ferreira, Anne-Karine Bouzier-Sore, Luc Pellerin, Juan P. Bolaños, Gilles Bonvento, L. Felipe Barros, Stephane H. R. Oliet, Aude Panatier, Giovanni Marsicano   +25 more
doaj   +1 more source

Computational analysis of a multi-varied biomimetic neural network

, 2021
Ces dernières années, les astrocytes apparaissent comme des éléments si impliqués dans la communication inter-neuronale, qu'ils sont de plus en plus considérés dans le couplage synaptique reliant les neurones et les synapses, constituant ainsi des ...
Vuillaume, Roman
core  

Calcium Signaling Mechanisms Mediate Clock-Controlled ATP Gliotransmission among Immortalized Rat SCN2.2 Cell Cultures

, 2010
The hypothalamus is an integral part of the brain's regulation of mammalian physiology and behavior. Among many functions, this regulatory center activates the sympathetic nervous system, maintains appropriate body temperature, controls food intake,
Burkeen, Jeffrey Franklin
core  

Astrocyte-mediated higher-order control of synaptic plasticity. [PDF]

Commun Biol
Menesse G, Millán AP, Torres JJ.
europepmc   +1 more source