Results 81 to 90 of about 1,835 (174)

NDRG2 phosphorylation provides negative feedback for SGK1-dependent regulation of a kainate receptor in astrocytes

open access: yesFrontiers in Cellular Neuroscience, 2015
Glutamate receptors play an important role in the function of astrocytes. Among their tasks is the regulation of gliotransmission, gene expression and exocytosis of the tissue-type plasminogen activator (tPA), which has an enhancing effect on NMDA ...
Veronika eMatschke   +7 more
doaj   +1 more source

Targeting necroptosis protects against astrocyte death and hippocampal sclerosis in experimental temporal lobe epilepsy

open access: yesThe Journal of Physiology, Volume 604, Issue 4, Page 1695-1707, 15 February 2026.
Abstract figure legend Experimentally induced status epilepticus induces microglial TNFα release, which binds to astrocytic TNFR1 and triggers activation of RIPK1/RIPK3/MLKL signalling, initiating necroptotic astrocytic death that contributes to the development of hippocampal sclerosis. Created with Biorender.com.
Zhou Wu   +3 more
wiley   +1 more source

Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss [PDF]

open access: yes, 2009
Astrocytes modulate neuronal activity by releasing chemical transmitters via a process termed gliotransmission. The role of this process in the control of behavior is unknown.
Haydon, P.G.   +29 more
core   +1 more source

Role for astroglial α1-adrenoreceptors in gliotransmission and control of synaptic plasticity in the neocortex [PDF]

open access: yes, 2015
Communication between neuronal and glial cells is thought to be very important for many brain functions. Acting via release of gliotransmitters, astrocytes can modulate synaptic strength.
Pankratov, Yuriy   +5 more
core   +1 more source

Astroglial glutamate transporters trigger glutaminergic gliotransmission

open access: yesThe Journal of Physiology, 2012
Rapid exchange of molecular signals between synapses and the surrounding astroglia has recently emerged as an essential player in regulating neural circuit activities in the brain. This conceptual leap was prompted in large part by early findings demonstrating that electrically non-excitable glia could, in fact, generate and propagate relatively rapid,
openaire   +3 more sources

Gliotransmission in the hippocampus, mechanisms and interaction with synaptic functions

open access: yes, 2011
SUMMARYAstrocytes represent the largest cell population in the human brain. In addition to a well established role as metabolic support for neuronal activity, in the last years these cells have been found to accomplish other important and, sometimes ...
Santello, M.
core   +1 more source

Synaptic Functions of Hemichannels and Pannexons: A Double-Edged Sword

open access: yesFrontiers in Molecular Neuroscience, 2018
The classical view of synapses as the functional contact between presynaptic and postsynaptic neurons has been challenged in recent years by the emerging regulatory role of glial cells.
Verónica Abudara   +8 more
doaj   +1 more source

Gliotransmission orchestrates neuronal type-specific axon regeneration [PDF]

open access: yes, 2019
SUMMARY Why closely related neuronal types differ in their axon regenerative abilities remains elusive. Here, we demonstrate gliotransmission determines such a difference in Drosophila larval sensory neurons.
Fei Wang   +7 more
openaire   +1 more source

Challenging the Dogma: Reevaluating the Role of Astrocyte Calcium Signaling in Physiology [PDF]

open access: yes, 2010
Gliotransmission represents one of the most important conceptual shifts in neuroscience in the past several decades. Gliotransmission refers to the process whereby glial cells release specific neurotransmitters that modulate synaptic transmission via pre-
Petravicz, Jeremy C.
core   +1 more source

Calcium Signaling Mechanisms Mediate Clock-Controlled ATP Gliotransmission among Immortalized Rat SCN2.2 Cell Cultures [PDF]

open access: yes, 2009
The hypothalamus is an integral part of the brain's regulation of mammalian physiology and behavior. Among many functions, this regulatory center activates the sympathetic nervous system, maintains appropriate body temperature, controls food intake, and ...
Burkeen, Jeffrey Franklin
core   +1 more source

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