A Patient With Coinheritance of Alpha-Globin Gene Triplication and IVSI-5 Mutation of Beta-Globin Gene [PDF]
Majid Naderi +5 more
openalex +1 more source
Highly Efficient Gene Expression in B Lymphocytes Mediating by Lentivirus Vector [PDF]
Gene transduction and expression efficiencies among several type cell lines were compared by using vesicular stomatitis virus-glycoprotein (VSV-G) pseudotyped human immunodeficiency virus type-1 (HIV-1) based lentivirus vector. Large discrepancies of the
Akira Tempaku
core +1 more source
Unveiling the Genetic Association Between Hemoglobin Concentration and Amyotrophic Lateral Sclerosis
This study identified a causal relationship between genetically predicted hemoglobin (Hb) concentration and amyotrophic lateral sclerosis (ALS) through Mendelian randomization (MR), and integrated RNA‐seq and RT‐qPCR analyses to highlight BACH1, FLVCR1, and TRIM58 as potential genes involved in this association.
Hongmei Luo +4 more
wiley +1 more source
Excess antisense RNA from infectious recombinant SV40 fails to inhibit expression of a transfected, interferon-inducible gene [PDF]
Kerr, I M, Kerr, S M, Stark, G R
core +1 more source
Protein Z is a vitamin K‐dependent anticoagulant with elusive molecular functions. Herein, it is shown that heme binds to protein Z and induces conformational changes. One histidine‐based heme‐binding motif is identified. High heme‐binding affinity and functional effects are demonstrated on protein level. These findings shed new light on the structural
Paula Lindemann, Marie‐T. Hopp
wiley +1 more source
α‐Thalassemia represents one of the most important genetic modulators of β‐hemoglobinopathies. During this last decade, the ongoing interest in characterizing genotype–phenotype relationships has yielded incredible insights into α‐globin gene regulation ...
Jim Vadolas +4 more
doaj +1 more source
Periodicity in the length of 3'-poly(A) tails form nativ globin mRNA of rabbit
John M. Kelly, Robert A. Cox
openalex +2 more sources
Filipino beta zero thalassaemia: a high Hb A2 beta zero thalassaemia resulting from a large deletion of the 5' beta globin gene region. [PDF]
Penelope Motum +3 more
openalex +1 more source
A Stable Bioisostere of Ester‐Linked Ubiquitin Chains Enables Decoding of Protein Interactors
An ester‐to‐amide analog of an ester‐linked ubiquitin dimer is chemically synthesized through a convergent approach involving the sequential chemoselective ligation of three peptide fragments generated through Fmoc‐based solid‐phase peptide synthesis. The hydrolysis‐resistant ubiquitin dimer served as a chemical probe in the identification of potential
Yoshinori Taguchi +9 more
wiley +1 more source
Different RNA patterns of globin and non-globin 40S heterogeneous nuclear RNA-protein complexes in chicken reticulocyte nuclei [PDF]
Haimei Huang, Chi‐Bom Chae
openalex +1 more source

