Results 21 to 30 of about 1,658 (163)
Comprehensive investigation in patients affected by globozoospermia [PDF]
Andrology, 2015 SummaryThe aim of this study was to provide a comprehensive genetic/phenotypic characterization of subjects suffering infertility owing to sperm macrocephaly (n = 3) or globozoospermia (n = 9) and to investigate whether the patients’ genetic status was correlated with the alteration of various sperm parameters.
C, Coutton, C, Arnoult, P F, Ray
openaire +9 more sources
Molecular Cytogenetics, 2020 Background Male infertility is an increasing medical concern worldwide. In most cases, genetic factors are considered as the main cause of the disease.
You-zhu Li +6 more
doaj +1 more source
Oxidative Stress-Related Programmed Cell Death in Male Infertility: Focussing on Ferroptosis. [PDF]
J Cell Mol MedABSTRACT Oxidative stress is a common occurrence in testicular cells of infertile men and is considered a significant cause of male reproductive dysfunction. The increase in reactive oxygen species (ROS) leads to impaired spermatogenesis by activating caspases and generating free radicals from mitochondria, resulting in DNA damage and cell death ...
Sanei-Ataabadi N +3 more
europepmc +2 more sources
Andrology, Volume 11, Issue 5, Page 808-815, July 2023., 2023 Abstract Background A safe, effective, and reversible nonhormonal male contraceptive drug is greatly needed for male contraception as well as for circumventing the side effects of female hormonal contraceptives. Phosducin‐like 2 (PDCL2) is a testis‐specific phosphoprotein in mice and humans.
Qiuji Ye +11 more
wiley +1 more source
Frontiers in Cell and Developmental Biology, 2021 Profilins (PFNs) are key regulatory proteins for the actin polymerization in cells and are encoded in mouse and humans by four Pfn genes. PFNs are involved in cell mobility, cell growth, neurogenesis, and metastasis of tumor cells.
Naila Umer +8 more
doaj +1 more source
Andrologia, Volume 2023, Issue 1, 2023., 2023 Multiple morphological abnormalities of sperm flagella (MMAF) indicate severe teratozoospermia. The fibrous sheath interacting protein 2 (FSIP2) plays an important role in the normal construction of the flagella. In this study, a novel compound heterozygous mutation site of FSIP2, involving c.272_275delinsAGGTTTTTATA (p.L92Vfster74) and c ...
Fang Gao +16 more
wiley +1 more source
Health Science Reports, Volume 5, Issue 5, September 2022., 2022 Abstract Background and Aims Several studies have shown that the length of ejaculatory abstinence alters sperm quality. However, the available data are conflicting and none seems to exist in a Nigerian population. The present study aims to compare the semen quality in normozoospermic and oligozoospermic semen samples of a homogenous Nigerian population,
Roland E. Akhigbe +3 more
wiley +1 more source
Journal of Human Reproductive Sciences, 2018 Globozoospermia, characterized by round-headed acrosomeless sperm, is a rare and severe form of teratozoospermia. We report a successful pregnancy in two cases of total globozoospermia after intracytoplasmic sperm injection (ICSI) with oocyte activation ...
Puneet Kaur Kochhar, Pranay Ghosh
doaj +1 more source
Physiological disturbances and histological damages of reproductive system in male rats resulted by metformin [PDF]
Caspian Journal of Environmental Sciences, 2022 The current study was designed to evaluate the effects of metformin in some physiological and histological parameters of reproductive system in the diabetic male rats experimentally. Forty rats were randomly divided into four groups. The (control) first
Fatima Aziz Mahdi Al-badry
doaj +1 more source
Clinical Genetics, Volume 102, Issue 1, Page 22-29, July 2022., 2022 Several genes are responsible for ovulatory disorders, especially for oocyte maturation defect with TUBB8 related to oocyte meiotic arrest, PATL2 associated to the retrieval of oocytes blocked at the germinal vesicle stage and ZP1 for which patients present no oocytes or atretic oocytes.
Corinne Loeuillet +8 more
wiley +1 more source