Results 21 to 30 of about 2,192 (198)

Ultrastructural Morphology of Sperm from Human Globozoospermia [PDF]

BioMed Research International, 2015
Globozoospermia is a rare disorder characterized by the presence of sperm with round head, lacking acrosome. Coiling tail around the nucleus has been reported since early human studies, but no specific significance has conferred it. By contrast, studies on animal models suggest that coiling tail around the nucleus could represent a crucial step of ...
RICCI, GIUSEPPE, Andolfi, L, Zabucchi, G, Luppi, S, Boscolo, R, Martinelli, M, ZWEYER, MARINA, TREVISAN, ELISA   +7 more
openaire   +7 more sources

Globozoospermia.

Kathmandu University Medical Journal
Male infertility may be due to low sperm concentration, poor sperm motility, or abnormal morphology. Among the factors involved in male infertility, there is a rare morphology disorder called "Globozoospermia".
L. Bhattarai, B. Gautam, BB Raut, S. Chettri   +3 more
semanticscholar   +3 more sources

DPY19L2 Deletion as a Major Cause of Globozoospermia [PDF]

The American Journal of Human Genetics, 2011
Globozoospermia, characterized by round-headed spermatozoa, is a rare (< 0.1% in male infertile patients) and severe teratozoospermia consisting primarily of spermatozoa lacking an acrosome. Studying a Jordanian consanguineous family in which five brothers were diagnosed with complete globozoospermia, we showed that the four out of five analyzed ...
Isabelle, Koscinski, Elias, Elinati, Camille, Fossard, Claire, Redin, Jean, Muller, Juan, Velez de la Calle, Françoise, Schmitt, Mariem, Ben Khelifa, Pierre F, Ray, Pierre, Ray, Zaid, Kilani, Christopher L R, Barratt, Stéphane, Viville   +12 more
openaire   +5 more sources

A Homozygous Deletion of the DPY19L2 Gene is a Cause of Globozoospermia in Men From the Republic of Macedonia

Balkan Journal of Medical Genetics, 2013
Globozoospermia is a rare but severe teratozoospermia, characterized by ejaculates consisting completely of round-headed spermatozoa that lack an acrosome or, in partial globozoospermia, containing a variable proportion (20.0-90.0%) of acrosomeless ...
Noveski P, Madjunkova S, Maleva I, Sotiroska V, Petanovski Z, Plaseska-Karanfilska D   +5 more
doaj   +2 more sources

Identification of a DPY19L2 Mutation Linking Globozoospermia to Congenital Heart Defects in a Consanguineous Family: A Genetic Analysis

Andrologia, Volume 2026, Issue 1, 2026.
Male infertility is a complex condition with significant genetic heterogeneity. Globozoospermia, a rare form of teratozoospermia characterized by round‐headed sperm, is frequently associated with mutations in the DPY19L2 gene.
Hongjing Li, Jun He, C. Chen, Zongjian Tan, Weiming Chen, Maobo Tian   +5 more
semanticscholar   +2 more sources

Comparison of Human Oocyte Activation Between Round-Headed Sperm Injection Followed by Calcium Ionophore Treatment and Normal Sperm Injection in a Patient With Globozoospermia

Frontiers in Endocrinology, 2020
Fertilization failure is common in patients with round-headed sperm, a form of globozoospermia. Artificial oocyte activation is able to assist oocyte fertilization after sperm injection in these patients.
Xiangli Niu, Qiuyan Ruan, Craig A. Witz, Weihua Wang   +3 more
doaj   +2 more sources

Globozoospermia

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2014
Globozoospermia is a teratozoospermia that has not the ability of sperm to fertilize an oocyte with its own state, observed in infertile male patients with a ratio of 0.1%.
Deniz Aka Satar, Raziye Narin
doaj   +3 more sources

Intracytoplasmic Sperm Injection Fertilization Rate Does Not Depend on the Proportion of Round-headed Sperm, Small-acrosomal Sperm, or Morphologically Normal Sperm in Patients with Partial Globozoospermia

Chinese Medical Journal, 2015
Background:. Generally, intracytoplasmic sperm injection (ICSI) may be the preferable method to treat partial globozoospermia, but whether there exist some correlations between ICSI fertilization rate and the proportion of round-headed sperm or ...
Ling-Ying Jiang, Ling-Yun Yang, Xiao-Mei Tong, Hai-Yan Zhu, Ya-Mei Xue, Wen-Zhi Xu, Yang Yang, Song-Ying Zhang   +7 more
doaj   +2 more sources

Phospholipase Cζ, the Molecular Spark of Fertilization and Male Infertility: Insights from Bench to Bedside [PDF]

Medicina
Phospholipase C zeta (PLCζ) has emerged as a pivotal sperm-specific factor responsible for triggering oocyte activation, a process essential for successful fertilization and early embryogenesis.
Aris Kaltsas, Maria-Anna Kyrgiafini, Zissis Mamuris, Fotios Dimitriadis, Athanasios Zachariou, Michael Chrisofos, Nikolaos Sofikitis   +6 more
doaj   +2 more sources

Successful pregnancies and a live birth after intracytoplasmic sperm injection in globozoospermia

Journal of Human Reproductive Sciences, 2009
Globozoospermia is a severe form of teratozoospermia characterized by round-headed acrosomeless spermatozoa. Here we present two successful pregnancies and a live birth after intracytoplasmic sperm injection.
Manish R Banker, Pravin M Patel, Bharat V Joshi, Preeti B Shah, Rakhi Goyal   +4 more
doaj   +2 more sources