Results 21 to 30 of about 2,311 (205)
Morphology of Partial Globozoospermia [PDF]
ABSTRACT: Total globozoospermia is a rare sperm morphology disorder that consists of 100% round‐headed, acrosomeless spermatozoa. There is also a larger group of patients whose sperm cells are partially acrosomeless. The aim of this investigation was to describe partial globozoospermia compared to total globozoospermia and normozoospermia.
Dam, A.H.D.M. +7 more
openaire +3 more sources
Molecular Analysis of DPY19L2, PICK1 and SPATA16 in Italian Unrelated Globozoospermic Men
This study aims to evaluate genetic contribution and sperm DNA fragmentation (SDF) in a cohort of 18 unrelated globozoospermic Italian men (Group G). Semen samples were assessed according to the WHO 2010 Laboratory Manual and compared with 31 fertile ...
Fabiana Faja +7 more
doaj +1 more source
Abstract Background A safe, effective, and reversible nonhormonal male contraceptive drug is greatly needed for male contraception as well as for circumventing the side effects of female hormonal contraceptives. Phosducin‐like 2 (PDCL2) is a testis‐specific phosphoprotein in mice and humans.
Qiuji Ye +11 more
wiley +1 more source
Multiple morphological abnormalities of sperm flagella (MMAF) indicate severe teratozoospermia. The fibrous sheath interacting protein 2 (FSIP2) plays an important role in the normal construction of the flagella. In this study, a novel compound heterozygous mutation site of FSIP2, involving c.272_275delinsAGGTTTTTATA (p.L92Vfster74) and c ...
Fang Gao +16 more
wiley +1 more source
Background Male infertility is an increasing medical concern worldwide. In most cases, genetic factors are considered as the main cause of the disease.
You-zhu Li +6 more
doaj +1 more source
An Overview of The Globozoospermia as A Multigenic Identified Syndrome [PDF]
Acrosome plays an integral role during fertilization and its absence in individuals with globozoospermia leads to failure of in vitro fertilization (IVF) and oocyte activation post-intracytoplasmic sperm injection (ICSI).
Parastoo Modarres +2 more
doaj +1 more source
Abstract Background and Aims Several studies have shown that the length of ejaculatory abstinence alters sperm quality. However, the available data are conflicting and none seems to exist in a Nigerian population. The present study aims to compare the semen quality in normozoospermic and oligozoospermic semen samples of a homogenous Nigerian population,
Roland E. Akhigbe +3 more
wiley +1 more source
Several genes are responsible for ovulatory disorders, especially for oocyte maturation defect with TUBB8 related to oocyte meiotic arrest, PATL2 associated to the retrieval of oocytes blocked at the germinal vesicle stage and ZP1 for which patients present no oocytes or atretic oocytes.
Corinne Loeuillet +8 more
wiley +1 more source
Mfsd14a disruption causes globozoospermia [PDF]
The Mfsd14a gene, previously called Hiat1, encodes a transmembrane protein of unknown function with homology to the solute carrier protein family. To study the function of the MFSD14A protein, mutant mice (Mus musculus, strain 129S6Sv/Ev) were generated ...
Colledge, William Henry +5 more
core +2 more sources
Ultrastructural Morphology of Sperm from Human Globozoospermia [PDF]
Globozoospermia is a rare disorder characterized by the presence of sperm with round head, lacking acrosome. Coiling tail around the nucleus has been reported since early human studies, but no specific significance has conferred it. By contrast, studies on animal models suggest that coiling tail around the nucleus could represent a crucial step of ...
RICCI, GIUSEPPE +7 more
openaire +5 more sources

