Novel sperm selection device on the basis of microfluidics improves usable blastocyst rates, embryo morphology, and morphokinetic patterns: sibling cohort prospective study [PDF]
F&S ReportsObjective: To assess the performance of a novel microfluidic sperm selection device, SwimCount Harvester (SCH), compared with the Swim-up (SU) method, analyzing both sperm quality and the laboratory’s key performance indicators.
Fernando Meseguer, M.Sc. +6 more
doaj +2 more sources
Recommendations for Human Sperm Morphology Assessment in 2025: An Expert Review From the French BLEFCO Group. [PDF]
AndrologyABSTRACT Background Numerous publications have questioned the lack of analytical reliability and clinical relevance of sperm morphology assessment for infertility workup and before use of assisted reproductive techniques (ART). There is a huge variability in the performance and interpretation of this test.
Gatimel N +14 more
europepmc +2 more sources
Globozoospermia revisited [PDF]
Human Reproduction Update, 2006 Abstract Globozoospermia is a rare (incidence <0.1%) but severe disorder in male infertility. Total globozoospermia is diagnosed by the presence of 100% round-headed spermatozoa lacking an acrosome. It is still unclear whether patients whose ejaculate contains both normal and globozoospermic cells (partial globozoospermia ...
Dam, A.H.D.M. +5 more
openaire +3 more sources
Assessment of DPY19L2 Deletion in Familial and Non-Familial Individuals with Globozoospermia and DPY19L2 Genotyping [PDF]
International Journal of Fertility and Sterility, 2016 Background Globozoospermia is a rare syndrome with an incidence of less than 0.1% among infertile men. Researchers have recently identified a large deletion, about 200 kbp, encompassing the whole length of DPY19L2 or mutations in SPATA16 and PICK1 genes ...
Parastoo Modarres +4 more
doaj +1 more source
Morphology of Partial Globozoospermia [PDF]
Journal of Andrology, 2011 ABSTRACT: Total globozoospermia is a rare sperm morphology disorder that consists of 100% round‐headed, acrosomeless spermatozoa. There is also a larger group of patients whose sperm cells are partially acrosomeless. The aim of this investigation was to describe partial globozoospermia compared to total globozoospermia and normozoospermia.
Dam, A.H.D.M. +7 more
openaire +3 more sources
Innovative all-in-one exome sequencing strategy for diagnostic genetic testing in male infertility: Validation and 10-month experience. [PDF]
AndrologyAbstract Background Current guidelines indicate that patients with extreme oligozoospermia or azoospermia should be tested for chromosomal imbalances, azoospermia factor (AZF) deletions and/or CFTR variants. For other sperm abnormalities, no genetic diagnostics are recommended.
Oud MS +12 more
europepmc +2 more sources
Assisted Oocyte Activation following Intracytoplasmic Sperm Injection: A Sensible Option for Infertile Couples with Severe Teratozoospermia [PDF]
International Journal of Fertility and Sterility, 2023 The intracytoplasmic sperm injection (ICSI) has significantly improved male factor infertility treatment; however, complete fertilization failure still occurs in 1-5% of ICSI treatment cycles mainly due to oocyte activation failure.
Marziyeh Tavalaee +3 more
doaj +1 more source
Molecular Analysis of DPY19L2, PICK1 and SPATA16 in Italian Unrelated Globozoospermic Men
Life, 2021 This study aims to evaluate genetic contribution and sperm DNA fragmentation (SDF) in a cohort of 18 unrelated globozoospermic Italian men (Group G). Semen samples were assessed according to the WHO 2010 Laboratory Manual and compared with 31 fertile ...
Fabiana Faja +7 more
doaj +1 more source
Globozoospermia: Is There a Role for Varicocele Repair? [PDF]
Journal of Andrology, 2007 Varicocele is one of the most common abnormalities associated with male infertility. Although a great deal has been written regarding the pathophysiology and management of this lesion, the role of varicocele repair in selected clinical situations may be difficult to determine.
Randall B, Meacham +3 more
openaire +2 more sources
Search for mutations involved in human globozoospermia* [PDF]
Human Reproduction, 2005 Globozoospermia is a severe form of teratozoospermia characterized by round-headed sperm with an absence of acrosomes. Family cases of globozoopermia suggest that this pathology has genetic origins, but the mode of inheritance remains unknown. So far, no responsible genes have been identified.
Pirrello, Olivier +5 more
openaire +2 more sources