Results 31 to 40 of about 2,192 (198)
Reproductive Biomedicine Online, 2022 RESEARCH QUESTION Would the use of genome-wide genotyping be an advantageous strategy to identify the molecular aetiology of two brothers from a non-consanguineous family, clinically diagnosed with total globozoospermia?
O. López‐Rodrigo +4 more
semanticscholar +2 more sources
Proteomic Research of Molecular Defects in Globozoospermia
PROTEOMICS – Clinical Applications, 2019 AbstractGlobozoospermia is a form of teratozoospermia characterized by round‐headed spermatozoa and lack of acrosome. These spermatozoa cannot penetrate the zona pellucida of the oocyte, resulting in unsuccessful fertilization and infertility. When intracytoplasmic sperm injection is performed, the fertilization rate tends to be low.
Simone Ferrero, Fabio Barra
openaire +3 more sources
ELAPOR1 mediated vesicle traffic is required for acrosome biogenesis and male fertility in mice [PDF]
Cellular and Molecular Life SciencesSpermiogenesis is the post-meiotic differentiation and morphological change of the haploid spermatids. Acrosome biogenesis is one of the key events of spermiogenesis, which generates a specialized membranous organelle crucial for shaping the balanced ...
Runze Ding +7 more
doaj +2 more sources
Assisted Reproduction Techniques, 2020 The DPY19L2 gene provides instructions for making a protein that is found in developing sperm cells. The DPY19L2 protein is involved in the development of the acrosome and elongation of the sperm head, which are integral steps in sperm cell maturation ...
O. A. M. Alqawasmeh, Christopher Barratt
semanticscholar +2 more sources
Globozoospermia syndrome: An update
Andrologia, 2019 Among the factors involved in male infertility, there is a rare morphology disorder called "globozoospermia" that is classified into total globozoospermia and partial globozoospermia (type I and type II, respectively).
F. Fesahat, R. Henkel, A. Agarwal
semanticscholar +3 more sources
Sperm chromatin quality and DNA integrity in partial versus total globozoospermia
Andrologia, 2018 Globozoospermia is a severe form of teratozoospermia with low incidence in infertile patients, considered as one of the important causes of male infertility.
Ali Reza Talebi
exaly +2 more sources
Acrosomal biogenesis in human globozoospermia: immunocytochemical, ultrastructural and proteomic studies [PDF]
Human Reproduction, 2012 Acrosome biogenesis is a key event in sperm differentiation that depends on the proper interaction between the Golgi complex and the nuclear envelope of early spermatids. We studied the development, structure and biochemical characteristics of human acrosomes in germ cells and spermatozoa from testicular biopsies and semen samples of fertile men and ...
Alvarez Sedó, Cristian +2 more
openaire +5 more sources
Male infertility due to globozoospermia [PDF]
Definitions, 2020 Male infertility due to globozoospermia is a male infertility due to sperm disorder characterized by the presence, in sperm, of a large majority of round-headed spermatozoa that lack the acrosome and have an aberrant nuclear membrane and midpiece defects.
semanticscholar +2 more sources
Protein disulfide isomerase A6 (PDIA6) is essential for acrosome biogenesis and male fertility in mice [PDF]
Cell Communication and SignalingBackground The family of protein disulfide isomerases (PDIs) are thiol oxidoreductases located predominantly in the endoplasmic reticulum that catalyze thiol-disulfide exchange for normal protein folding.
Xiaofeng Yan +6 more
doaj +2 more sources
Study of Sperm Chromatin in Infertile Men with Globozoospermia: A Systematic Review Article
Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2019 Background and Aim: Globozoospermia is a severe sperm morphological abnormality in men that characterized by round-headed spermatozoa with low or absence acrosome structure in their sperm samples.
Marziyeh Tavalaee +2 more
doaj +1 more source