Results 31 to 40 of about 2,311 (205)
Current methods to analyze lysosome morphology, positioning, motility and function
Traffic, Volume 23, Issue 5, Page 238-269, May 2022., 2022 Lysosomes play essential roles beyond their well‐known degradative function, including nutrient sensing, intracellular signalling and metabolism. To better understand these functions, it is essential to employ the best methodological approaches and know their advantages and limitations.
Duarte C. Barral +32 more
wiley +1 more source
Frontiers in Cell and Developmental Biology, 2021 Profilins (PFNs) are key regulatory proteins for the actin polymerization in cells and are encoded in mouse and humans by four Pfn genes. PFNs are involved in cell mobility, cell growth, neurogenesis, and metastasis of tumor cells.
Naila Umer +8 more
doaj +1 more source
Is there a relationship between sperm chromosome abnormalities and sperm morphology? [PDF]
, 2006 This review explores the relationship between sperm chromosomal constitution and morphology. With the advent of techniques for obtaining information on the chromosome complements of spermatozoa, this relationship has been studied in fertile men and in ...
Ko Evelyn, Sun Fei, Martin Renée H
core +2 more sources
Search for mutations involved in human globozoospermia* [PDF]
Human Reproduction, 2005 Globozoospermia is a severe form of teratozoospermia characterized by round-headed sperm with an absence of acrosomes. Family cases of globozoopermia suggest that this pathology has genetic origins, but the mode of inheritance remains unknown. So far, no responsible genes have been identified.
Pirrello, Olivier +5 more
openaire +2 more sources
Microscopy Research and Technique, Volume 85, Issue 4, Page 1454-1464, April 2022., 2022 The GOPC protein is involved in the formation of the acrosome and the deletion of the gene that encodes it results in globozoospermia. In this study we have analyzed the expression of the acrosomal protein ZP3R in spermatogenesis of wild type individuals compared to sterile individuals lacking GOPC and consequently showing globozoospermia.
Maider Bizkarguenaga +4 more
wiley +1 more source
DNA damage in human sperm: The sperm chromosome assay
Reproductive Medicine and Biology, Volume 21, Issue 1, January/December 2022., 2022 This review explains with the data reported by studies with the sperm chromosome assays how and when DNA damage, which contributes to pre‐ and post‐implantation embryonic loss, occurs in human sperm. The sperm chromosome assay is superior to other assays that directly detect sperm DNA damage (TUNEL assays, Comet assays, and the acridine orange test ...
Seiji Watanabe
wiley +1 more source
Journal of Human Reproductive Sciences, 2018 Globozoospermia, characterized by round-headed acrosomeless sperm, is a rare and severe form of teratozoospermia. We report a successful pregnancy in two cases of total globozoospermia after intracytoplasmic sperm injection (ICSI) with oocyte activation ...
Puneet Kaur Kochhar, Pranay Ghosh
doaj +1 more source
Physiological disturbances and histological damages of reproductive system in male rats resulted by metformin [PDF]
Caspian Journal of Environmental Sciences, 2022 The current study was designed to evaluate the effects of metformin in some physiological and histological parameters of reproductive system in the diabetic male rats experimentally. Forty rats were randomly divided into four groups. The (control) first
Fatima Aziz Mahdi Al-badry
doaj +1 more source
High incidence of chromosomal abnormalities in large-headed and multiple-tailed spermatozoa [PDF]
, 2006 Rodrigo Vivo, Lorena, lorovi@alumni.uv.es ; Prados Dodd, Nicolas, Nicolas.Prados@uv.es ; Gil Salom, Manuel Luis, Manuel.Gil-Salom@uv.es ; Remohi Gimenez, Jose Alejandro, J.Alejandro.Remohi@uv ...
Gil Salom, Manuel +6 more
core +2 more sources
Molecular basis of the morphogenesis of sperm head and tail in mice
Reproductive Medicine and Biology, Volume 21, Issue 1, January/December 2022., 2022 The molecular mechanism of formation of the sperm head and tail has been clarified using the mouse as a model. These studies will help to better understand the diversity of sperm morphology and the causes of male infertility. Abstract Background The spermatozoon has a complex molecular apparatus necessary for fertilization in its head and flagellum ...
Keiichiro Yogo
wiley +1 more source