Results 31 to 40 of about 1,658 (163)
DPY19L2 Deletion as a Major Cause of Globozoospermia [PDF]
The American Journal of Human Genetics, 2011 Globozoospermia, characterized by round-headed spermatozoa, is a rare (< 0.1% in male infertile patients) and severe teratozoospermia consisting primarily of spermatozoa lacking an acrosome. Studying a Jordanian consanguineous family in which five brothers were diagnosed with complete globozoospermia, we showed that the four out of five analyzed ...
Isabelle, Koscinski +12 more
openaire +4 more sources
Frontiers in Endocrinology, 2020 Fertilization failure is common in patients with round-headed sperm, a form of globozoospermia. Artificial oocyte activation is able to assist oocyte fertilization after sperm injection in these patients.
Xiangli Niu +3 more
doaj +1 more source
Evaluation of Protamine Deficiency and DNA Fragmentation in Two Globozoospermia Patients Undergoing ICSI [PDF]
International Journal of Fertility and Sterility, 2007 The aim of this report has been evaluating protamine content and DNA integrity of two patients with globozoospermia undergoing Intra Cytoplasmic Sperm Injection (ICSI).Semen analysis was carried out according to WHO criteria. Protamine deficiency and DNA
Mohammad Reza Deemeh +3 more
doaj +1 more source
Redox Biology, 2021 Fibrous sheath interacting protein 1 (Fsip1) is a cytoskeletal structural protein of the sperm flagellar proteome. A few studies have reported that it plays a vital role in the tumorigenesis and cancer progression. However, little is known about the role
Yaser Gamallat +14 more
doaj +1 more source
Chinese Medical Journal, 2015 Background:. Generally, intracytoplasmic sperm injection (ICSI) may be the preferable method to treat partial globozoospermia, but whether there exist some correlations between ICSI fertilization rate and the proportion of round-headed sperm or ...
Ling-Ying Jiang +7 more
doaj +1 more source
How exome sequencing improves the diagnostics and management of men with non-syndromic infertility. [PDF]
AndrologyAbstract Male infertility affects approximately 17% of all men and represents a complex disorder in which not only semen parameters such as sperm motility, morphology, and number of sperm are highly variable, but also testicular phenotypes range from normal spermatogenesis to complete absence of germ cells.
Stallmeyer B, Dicke AK, Tüttelmann F.
europepmc +2 more sources
Dynamics of Sun5 localization during spermatogenesis in wild type and Dpy19l2 knock-out mice indicates that Sun5 is not involved in acrosome attachment to the nuclear envelope. [PDF]
PLoS ONE, 2015 The acrosome is an organelle that is central to sperm physiology and a defective acrosome biogenesis leads to globozoospermia, a severe male infertility. The identification of the actors involved in acrosome biogenesis is therefore particularly important
Sandra Yassine +6 more
doaj +1 more source
Ultrastructural Morphology of Sperm from Human Globozoospermia [PDF]
BioMed Research International, 2015 Globozoospermia is a rare disorder characterized by the presence of sperm with round head, lacking acrosome. Coiling tail around the nucleus has been reported since early human studies, but no specific significance has conferred it. By contrast, studies on animal models suggest that coiling tail around the nucleus could represent a crucial step of ...
RICCI, GIUSEPPE +7 more
openaire +5 more sources
, 2023 Clinical Genetics, Volume 103, Issue 5, Page 612-614, May 2023.
Guillaume Martinez +7 more
wiley +1 more source
Balkan Journal of Medical Genetics, 2013 Globozoospermia is a rare but severe teratozoospermia, characterized by ejaculates consisting completely of round-headed spermatozoa that lack an acrosome or, in partial globozoospermia, containing a variable proportion (20.0-90.0%) of acrosomeless ...
Noveski P +5 more
doaj +1 more source