Results 11 to 20 of about 199,077 (362)
Glucocorticoid Receptor and Adipocyte Biology. [PDF]
Nuclear Receptor Research, 2018 Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A +2 more
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Glucocorticoid receptors and depression. [PDF]
BMJ, 1986 The number of glucocorticoid receptor sites in lymphocytes was estimated and plasma cortisol concentrations measured in 17 depressed patients, 12 patients with chronic schizophrenia, and 31 healthy control subjects. The number of receptor sites was significantly lower in the depressed patients than in either the controls or the patients with chronic ...
Lawrence J. Whalley +5 more
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The glucocorticoid receptor resource [PDF]
Nucleic Acids Research, 1996 The glucocorticoid receptor resource focuses on the structure-function relationships of the glucocorticoid receptor. As well as links to sequence and bibliographic databases via the World Wide Web, the database contains sequence comparisons of receptors from different species and source information for glucocorticoid receptor clones, probes, cell lines
Elisabeth D. Martinez, Mark Danielsen
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Mitochondrial Glucocorticoid Receptors and Their Actions [PDF]
International Journal of Molecular Sciences, 2021 Mitochondria are membrane organelles present in almost all eukaryotic cells. In addition to their well-known role in energy production, mitochondria regulate central cellular processes, including calcium homeostasis, Reactive Oxygen Species (ROS) generation, cell death, thermogenesis, and biosynthesis of lipids, nucleic acids, and steroid hormones ...
Paraskevi Moutsatsou +1 more
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How the glucocorticoid receptor contributes to platinum-based therapy resistance in solid cancer
Nature Communications, 2021 Synthetic glucocorticoids serve as co-medication against solid malignant tumors. However, glucocorticoid receptor activation may promote unsolicited cancer resistance to chemotherapy.
Dorien Clarisse, Karolien De Bosscher
doaj +1 more source
Cooperativity of Glucocorticoid Response Elements Located Far Upstream of the Tyrosine Aminotransferase Gene [PDF]
, 1987 Two glucocorticoid response elements (GREs) located 2.5 kb upstream of the transcription initiation site of the tyrosine aminotransferase gene were identified by gene transfer experiments and shown to bind to purified glucocorticoid receptor.
Banerji +41 more
core +1 more source
A thyroid hormone receptor-dependent glucocorticoid induction. [PDF]
, 1994 Glucocorticoid and thyroid hormones exert their effects in many body tissues by binding to their respective receptors. The search for possible cross-talking mechanisms in overlapping target cells led to the discovery of synergism between a thyroid ...
Leers, Joerg +3 more
core +1 more source
Glucocorticoid Receptor Signaling in Diabetes [PDF]
International Journal of Molecular Sciences, 2021 Stress and depression increase the risk of Type 2 Diabetes (T2D) development. Evidence demonstrates that the Glucocorticoid (GC) negative feedback is impaired (GC resistance) in T2D patients resulting in Hypothalamic-Pituitary-Adrenal (HPA) axis hyperactivity and hypercortisolism.
Ioanna Kokkinopoulou +2 more
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Glucocorticoid guides mobilization of bone marrow stem/progenitor cells via FPR and CXCR4 coupling
Stem Cell Research & Therapy, 2021 Background Our previous studies have proved the efficient exogenous repairing responses via bone marrow stem and progenitor cells (BMSPCs). However, the trafficking of endogenous bone marrow stem and progenitor cells to and from the bone marrow (BM) is a
Wenting Gao +6 more
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NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells [PDF]
, 2015 Glucocorticoids are universally used in the treatment of acute lymphoblastic leukemia (ALL), and resistance to glucocorticoids in leukemia cells confers poor prognosis.
A Holleman +94 more
core +2 more sources