Results 91 to 100 of about 15,165 (218)

Effects of three different diets on glucose, insulin, triglycerides and glucose-dependent insulinotropic-polypeptide (GIP).

, 2013
Effects of a low-fat diet (open circles, regular lines), low-carbohydrate diet (open squares, dashed lines) and a Mediterranean-type diet (open triangles, dotted lines) with similar total energy intake as the low-fat and low-carbohydrate diets contained ...
Bekim Bunjaku (490259), Christine Jaredsson (490258), Hanna Fernemark (490257), Ulf Rosenqvist (490260), Fredrik H. Nystrom (490261), Hans Guldbrand (490262)   +5 more
core   +1 more source

GLP‐1‐Based Therapies in Type 1 Diabetes: Emerging Evidence on Cardiovascular, Renal, and Safety Outcomes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Individuals living with type 1 diabetes (T1D) are at increased risk for cardiovascular (CV) and renal complications, yet therapeutic strategies specifically targeting cardiorenal risk reduction in this population remain limited. The role of glucagon‐like peptide‐1 (GLP‐1)‐based therapies in T1D remains unclear.
Anastasios Tentolouris, Djordje S. Popovic, Alexandros L. Liarakos, Alexandros Briasoulis, Nikolaos Papanas, Theocharis Koufakis   +5 more
wiley   +1 more source

Metabolomic linkage reveals functional interaction between glucose-dependent insulinotropic polypeptide and ghrelin in humans

Rudovich NN, Nikiforova VJ, Otto B, Pivovarova O, Gogebakan, Erban A, Mohlig M, Weickert MO, Spranger J, Tschop MH, Willmitzer L, Nauck M, Pfeiffer AF.
Erban, A., Spranger, Joachim, Weickert, Martin O., Pfeiffer, Andreas F. H., Gogebakan, O., Möhlig, Matthias, Nikiforova, V. J., Tschop, M. H., Willmitzer, Lothar, Otto, B., Rudovich, Natalia N., Nauck, Matthias, Pivovarova, Olga   +12 more
core   +1 more source

Glucose-dependent insulinotropic polypeptide - Beyond the enteroinsular axis?

, 2006
Purpose of review: Glucose-dependent insulinotropic polypeptide (GIP) plays an important role in the enteroinsular axis, stimulating insulin secretion. In addition, it has extrapancreatic actions, which may have pathophysiological relevance.
Robertson, MD, Johnston, KL, Morgan, LM
core   +2 more sources

Acute exogenous acyl-GIP treatment enhances lipid handling and fatty acid oxidation by involving brown fat

EMBO Reports
The contribution of glucose-dependent insulinotropic polypeptide receptor (GIPR) signalling in brown adipose tissue (BAT) remains underexplored. We studied the acute effects of exogenous acyl-GIP (1 nmol/kg) administration on whole-body lipid handling ...
Sulayman A Lyons, Micah B S Lea, Mihir Parikh, Zhengzhang Guo, Samrin Kagdi, Abigail R Bisnauth, Jonathan R Pitino, Sabrina Ziai, Negar Mir, Aidan D Tyrrell, Yan Fu, Chuck T Chen, Adam H Metherel, Richard P Bazinet, Bin Yang, Patrick J Knerr, Jonathan D Douros, Jonathan E Campbell, Jacqueline L Beaudry   +18 more
doaj   +1 more source

Tirzepatide Is Associated With Improved Metabolic Outcomes in People With Type 1 Diabetes and Overweight or Obesity: A Retrospective Cohort Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To evaluate the effect of tirzepatide on body weight, glycaemic control, insulin requirements, continuous glucose monitoring (CGM) metrics and cardiorenal parameters in adults with Type 1 diabetes (T1D) and overweight or obesity. Materials and Methods In this retrospective matched cohort study, adults with T1D, BMI ≥ 27 kg/m2, CGM use and
Amanda R. Purcell, Matilda S. G. Longfield, Natassia Rodrigo, Sarah J. Glastras   +3 more
wiley   +1 more source

Effect of phenylbutazone administration on the enteroinsular axis in horses with insulin dysregulation

Journal of Veterinary Internal Medicine
Background Phenylbutazone is prescribed for laminitis‐associated pain and decreases glucose and insulin responses to an oral glucose test (OGT) in horses with insulin dysregulation (ID).
Kate L. Kemp, Jazmine E. Skinner, François‐René Bertin   +2 more
doaj   +1 more source

Early Weight Regain After GLP‐1 Receptor Agonist Discontinuation: Mechanisms and Implications for Treatment De‐Escalation Strategies

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) have transformed the pharmacological management of obesity, producing substantial and sustained weight loss during active treatment. However, discontinuation of therapy is frequently followed by significant weight regain, raising important questions regarding the durability of treatment ...
M. A. Damhof, F. H. van Bruggen, E. N. van Roon   +2 more
wiley   +1 more source

The effect of exogenous glucose-dependent insulinotropic polypeptide in combination with glucagon-like peptide-1 onglycemia in the critically Ill [PDF]

, 2013
OBJECTIVE: Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) have additive insulinotropic effects when coadministered in health.
Umapathysivam, MM, Zaknic, AV, Chapman, MJ, Summers, MJ, Fraser, JD, Rayner, CK, Lee, MY, Meier, JJ, Sundararajan, K, Horowitz, M, Deane, AM   +10 more
core   +1 more source

Adaptive islet biology and comprehensive incretin physiology: Emerging perspectives from Asia and Europe

Journal of Diabetes Investigation, EarlyView.
Adaptive islet biology and incretin physiology provide a framework linking diverse diabetes phenotypes, with advances in β‐cell stress adaptation, intra‐islet communication, receptor‐resolved biology, and β‐cell mass imaging. By integrating clinical perspectives from Asia and Europe with multiscale islet‐cell biology, these insights may support ...
Takaaki Murakami, Daniela Nasteska, David J. Hodson, Yuji Yamazaki, Daisuke Yabe, Yutaka Seino   +5 more
wiley   +1 more source