Results 61 to 70 of about 1,256,400 (271)

Immobilized Trienzymatic System with Enhanced Stabilization for the Biotransformation of Lactose

Molecules, 2017
The use of ketohexose isomerases is a powerful tool in lactose whey processing, but these enzymes can be very sensitive and expensive. Development of immobilized/stabilized biocatalysts could be a further option to improve the process.
Pedro Torres, Francisco Batista-Viera
doaj   +1 more source

Spray‐Dried Engineered Escherichia coli Whole‐Cell Biocatalysts Enable Cell Recycling and In Vivo α‐Ketoglutarate and NADPH Regeneration for Efficient Codeine Manufacture

Biotechnology and Bioengineering, EarlyView.
ABSTRACT A recombinant whole‐cell biocatalytic approach provides several advantages over isolated enzymes, such as improved enzyme stability, in vivo cofactor regeneration, and the facilitation of cascade reactions within a single cell. Whole‐cell biocatalysis has gained attention in medicinal opioid production, due to its technical and economic ...
Ali Jahanian, Carlos Horacio Luna‐Flores, Xu Li, Sally L. Gras, Robert E. Speight   +4 more
wiley   +1 more source

Structural Analysis of Xylose Isomerase from Streptomyces avermitilis

Crystals
Xylose isomerase (XI, also known as glucose isomerase) is an oxidoreductase that interconverts aldoses and ketoses. XI catalyzes the reversible isomerization of D-glucose and D-xylose into D-fructose and D-xylulose, respectively.
Ki Hyun Nam
doaj   +1 more source

Mitochondria‐endoplasmic reticulum organelle glue as maturation promoter for origination/dimensional dual‐cross cardiomyocytes

BMEMat, EarlyView.
Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang, Hao Sun, Chenqi Duan, Jiajia Chang, Yuxing Wang, Ming Zhao, Huiyue Zhao, Shan Lu, Yang Yang, Da Huo   +9 more
wiley   +1 more source

Very Low Nucleation Rates of Glucose Isomerase Crystals under Microgravity in the International Space Station

Crystals, 2019
In situ observation of the nucleation and growth of glucose isomerase (GI) crystals under microgravity was conducted using an optical microscope during the first flight of the Advanced Nano Step project undertaken in the International Space Station (ISS).
Yoshihisa Suzuki, Takahisa Fujiwara, Katsuo Tsukamoto, Seijiro Fukuyama, Taro Shimaoka, Kazuma Tsuchiya, Ai Ninomiya, Yumiko Murakumo, Akiho Ikeuchi, Hitomi Minamizono, Tomokazu Yamazaki, Takehiko Sone, Tetsuya Sakashita, Masae Nagai, Yasutomo Arai   +14 more
doaj   +1 more source

Activity of Glucose Isomerase from Bacillus thuringiensis under Different Treatments

, 2016
Bacillus thuringiensis is a Gram-positive bacterium naturally found in soil, water and grain dust, and can be cultivated in liquid, solid and semi-solid media. Glucose isomerase (EC.
H. El-Shora, Ahmed M. El-Shobaky, Jehan E Ghoneim   +2 more
semanticscholar   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Novel Devices for Transporting Protein Crystals to the Synchrotron Facilities and Thermal Protection of Protein Crystals

Crystals, 2018
In this article, we use novel and non-conventional devices, based on polyolefins that help to increase the thermal protection of protein crystals in their crystallization conditions for crystallographic applications.
Andrea Flores-Ibarra, Camila Campos-Escamilla, Yasel Guerra, Enrique Rudiño-Piñera, Nicola Demitri, Maurizio Polentarutti, Mayra Cuéllar-Cruz, Abel Moreno   +7 more
doaj   +1 more source

Disrupting glucose-6-phosphate isomerase fully suppresses the “Warburg effect” and activates OXPHOS with minimal impact on tumor growth except in hypoxia

OncoTarget, 2017
As Otto Warburg first observed, cancer cells largely favor fermentative glycolysis for growth even under aerobic conditions. This energy paradox also extends to rapidly growing normal cells indicating that glycolysis is optimal for fast growth and ...
Monique M. Cunha de Padua, Giulia Delodi, M. Vucetic, J. Durivault, Valérie Vial, Pascale Bayer, G. Noleto, N. Mazure, M. Ždralević, J. Pouysségur   +9 more
semanticscholar   +1 more source

A New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation

Food Chemistry International, EarlyView.
Preserving functional β‐cells via natural products offers promising strategy for diabetes treatment. ABSTRACT A defining characteristic of diabetes is β‐cell failure, in which β‐cells cannot modulate insulin secretion to compensate for escalating insulin resistance, pushing forward disease development.
Yi‐San Lee, Tien‐Fen Kuo, Chun‐Yen Yang, Greta Yang, Wen‐Chin Yang   +4 more
wiley   +1 more source