miRNA-218 Targets Lipin-1 and Glucose Transporter Type 4 Genes in 3T3-L1 Cells Treated With Lopinavir/Ritonavir [PDF]
Frontiers in Pharmacology, 2019 Background: Metabolic complications represent a common and serious problem associated with HIV infection and combined Antiretroviral Therapy (cART). Alterations in body fat distribution are associated with significantly increased risks of (i) metabolic ...
Elena Bresciani +10 more
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High Estradiol Differentially Affects the Expression of the Glucose Transporter Type 4 in Pelvic Floor Muscles of Rats [PDF]
International Neurourology Journal, 2018 Purpose To characterize the relationship between serum estradiol levels and the expression of glucose transporter type 4 (Glut4) in the pubococcygeus and iliococcygeus muscles in female rats.
María de los Ángeles Carrasco-Ruiz +7 more
doaj +5 more sources
Chronic Hyperglycaemia Inhibits Tricarboxylic Acid Cycle in Rat Cardiomyoblasts Overexpressing Glucose Transporter Type 4. [PDF]
Int J Mol Sci, 2022 An oversupply of nutrients with a loss of metabolic flexibility and subsequent cardiac dysfunction are hallmarks of diabetic cardiomyopathy. Even if excess substrate is offered, the heart suffers energy depletion as metabolic fluxes are diminished. To study the effects of a high glucose supply, a stably glucose transporter type 4 (GLUT4)-overexpressing
Stratmann B +5 more
europepmc +4 more sources
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2023 Introduction: Glucose transporter type 4 (GLUT4) is a membrane glucose transporter that is influenced by insulin signaling and muscle contraction.
Akbar Ghalavand, Marya Rahmani Ghobadi
doaj +3 more sources
Understanding glucose transporter type 4, aka GLUT4: a novel review
Revista Mexicana de Endocrinología, Metabolismo y NutriciónGlucose transporter (GLUT4), discovered in 1988, is primarily located in adipocytes and muscle cells. Its unique transport mechanism is characterized by a 10-fold increase in exocytosis rate, which is dependent on insulin.
Karen De La Vega-Moreno +1 more
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Effect of phytase on intestinal phytate breakdown, plasma inositol concentrations, and glucose transporter type 4 abundance in muscle membranes of weanling pigs1. [PDF]
J Anim Sci, 2019 Abstract The objective of this present study was to determine the effects of phytase dosing on growth performance, mineral digestibility, phytate breakdown, and the level of glucose transporter type 4 (GLUT4) in muscle plasma membranes of weanling pigs. A total of 160 barrows were used in a randomized completely block design and assigned
Lu H +6 more
europepmc +6 more sources
Red rice koji extract alleviates hyperglycemia by increasing glucose uptake and glucose transporter type 4 levels in skeletal muscle in two diabetic mouse models [PDF]
Food & Nutrition Research, 2020 Background: Red rice koji (RRK), prepared by growing Monascus species on steamed rice, has been reported to lower blood glucose levels in diabetic animal models. However, the action mechanism is not yet completely understood.
Takakazu Yagi +10 more
doaj +5 more sources
MRNA Expression of Adipocytokines and Glucose Transporter Type 4 (GLUT4) in Adipose Tissue in Women With and Without Polycystic Ovary Syndrome [PDF]
J Endocr Soc, 2021 Abstract Background: The main feature of polycystic ovary syndrome (PCOS) is hyperandrogenism, adipocytes hypertrophy and chronic low-grade inflammation. It is known that PCOS is closely linked to functional dysfunction in adipose tissue, which in turn are connected with metabolic disturbances such as insulin resistance.
Ozga K +4 more
europepmc +3 more sources
Glucose transporter 4 gene expression in peripheral blood leukocytes in type 2 diabetes mellitus
Bangabandhu Sheikh Mujib Medical University Journal, 2019 The purpose of this study was to examine the status of glucose transporter type-4 (GLUT4) gene expression in the peripheral blood leukocytes of type 2 diabetic patients and explore the correlation of GLUT4 expression with homeostasis model assessment ...
Shahana Jasmin +4 more
doaj +3 more sources
Magnesium upregulates insulin receptor and glucose transporter-4 in streptozotocin-nicotinamide-induced type-2 diabetic rats [PDF]
Endocrine Regulations, 2018 Objective. We investigated the effects of magnesium supplementation on glucose tolerance, insulin sensitivity, oxidative stress as well as the concentration of insulin receptor and glucose transporter-4 in streptozotocin-nicotinamide induced type-2 ...
Morakinyo Ayodele Olufemi +2 more
doaj +3 more sources