Results 91 to 100 of about 9,009 (166)
MoleculesGaucher disease (GD) is a rare genetic metabolic disorder characterized by a dysfunction of the lysosomal glycoside hydrolase glucocerebrosidase (GCase) due to mutations in the gene GBA1, leading to the cellular accumulation of glucosylceramide (GlcCer).
Costanza Ceni +10 more
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Targeting Sphingolipids in Breast Cancer: From Tumor Biology to Therapeutic Strategies. [PDF]
Oncol ResKim MH, Huh B, Park JW, Park WJ.
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Pathological Protein Targets in Parkinson's Disease: Progress Towards the Development of Disease-Modifying Therapies. [PDF]
CNS DrugsDzamko N.
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Transport and Translocation of Glucosylceramide
, 2007 Glycosphingolipids (GSL) are important determinants of the functional organization of cellular membranes. They are controlled by the spatial organization of their metabolism and by specificity in transport. The aim of this thesis was to gain insight into the function of membrane lipids by learning more about their localization and intracellular ...
openaire +2 more sources
Central Roles of Glucosylceramide in Driving Cancer Pathogenesis. [PDF]
Int J Mol SciZhao X, Pandey MK.
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Mac-/Lactosylceramide regulates intestinal homeostasis and secretory cell fate commitment by facilitating Notch signaling. [PDF]
ElifeTang K +8 more
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Underlying Mechanisms of GBA1 in Parkinson's Disease and Dementia with Lewy Bodies: Narrative Review. [PDF]
Genes (Basel)Bougea A.
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Sphingolipids in Gaucher disease: a systematic review. [PDF]
Orphanet J Rare DisLake A, Fuller M.
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