Results 81 to 90 of about 9,362 (180)

Glucosylceramide [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Glucosylceramides and kidney disease

, 2017
Glucosylceramides are part of the wider family of glycosylceramides. Glucosylceramide synthase catalyzes the incorporation of a single glucose residue into ceramide to yield glucosylceramide. Glucosylceramide is known as a precursor for globotriaosylceramide (Gb3). In the cell membrane, Gb3 acts a receptor for verotoxin and plays a key role in allowing
Ortiz,Alberto, Sanchez-Nino,Maria Dolores   +1 more
openaire   +1 more source

Drosophila Glucosylceramide Synthase [PDF]

Journal of Biological Chemistry, 2004
Ayako Kohyama-Koganeya, Takeshi Sasamura, Eriko Oshima, Emiko Suzuki, Shoko Nishihara, Ryu Ueda, Yoshio Hirabayashi   +6 more
openaire   +1 more source

Transport and Translocation of Glucosylceramide

, 2007
Glycosphingolipids (GSL) are important determinants of the functional organization of cellular membranes. They are controlled by the spatial organization of their metabolism and by specificity in transport. The aim of this thesis was to gain insight into the function of membrane lipids by learning more about their localization and intracellular ...
openaire   +2 more sources

Potential of 3D Skin Models and N/TERT-2G Cell Line in Genetic Research on Autosomal Recessive Nonsyndromic Epidermal Differentiation Disorders. [PDF]

Exp Dermatol
Hsu-Rehder HH, Glocker C, Aldrian C, Dikici E, Wilde GS, Stavila M, Jonca N, Kollár B, Eisenhardt SU, Fischer J.   +9 more
europepmc   +1 more source

Plasma Glucosylsphingosine in GBA1 E365K, N409S, and L483P Heterozygous Mutation Carriers. [PDF]

Mov Disord
Agin-Liebes J, Haimovich A, Griep R, Hatcher NG, Yao L, Waters C, Padmanabhan S, Alcalay RN.   +7 more
europepmc   +1 more source

ASAH2 deficiency affects sphingolipid homeostasis and neuromotor control, causing a progressive neurological disorder. [PDF]

HGG Adv
Scala M, Sahu RK, Severino M, Traverso M, Iacomino M, Pedemonte M, Santorelli F, Tozza S, Zara F, Fiorillo C, Chung HL.   +10 more
europepmc   +1 more source

From Lysosomal Storage to Neurodegeneration: Sphingolipid Signaling as a Driver of CNS Pathology and Biomarker Strategy in Neuronopathic Gaucher Disease. [PDF]

Int J Mol Sci
Casazza K, Kartha RV, Jarnes JR.
europepmc   +1 more source

Targeted delivery of glucocerebrosidase to lysosomes: The LYSOTAC (LYSOsome-TArgeting Chimera) technology. [PDF]

Asian J Pharm Sci
Kim HY, Choi EN, Lee GE, Yoon S, Mun SR, Jung EJ, Kim M, Lim H, Kang YJ, Park WJ, Kwon YT, Park JW.   +11 more
europepmc   +1 more source

The Race to Salvage Glucocerebrosidase: Understanding Small-Molecule Therapies for GBA1-Associated Parkinsonism. [PDF]

Mov Disord
Henderson MJ, Chen TC, Glasstetter LM, Chen Y, Marugan JJ, Sidransky E.   +5 more
europepmc   +1 more source