Results 41 to 50 of about 2,629 (119)
Glucosylceramide modulates membrane traffic along the endocytic pathway. [PDF]
, 2002 Glycosphingolipids are endocytosed and targeted to the Golgi apparatus, but are mistargeted to lysosomes in numerous sphingolipidoses. Substrate reduction therapy utilizes imino sugars to inhibit glucosylceramide synthase and potentially abrogate the ...
Platt, Frances +14 more
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Clinical, Cosmetic and Investigational Dermatology, 2022 Toshihiko Enomoto, Ayana Kojima-Nakamura, Kazuya Kodaira, Yoshifumi Oguro, Atsushi Kurahashi Hakkaisan Brewery Co., Ltd, Minamiuonuma, Niigata, JapanCorrespondence: Atsushi Kurahashi, Hakkaisan Brewery Co., Ltd, 1051 Nagamori, Minamiuonuma, Niigata, 949 ...
Enomoto T +4 more
doaj
Biological Roles Played by Sphingolipids in Dimorphic and Filamentous Fungi
mBio, 2018 Filamentous and dimorphic fungi cause invasive mycoses associated with high mortality rates. Among the fungal determinants involved in the establishment of infection, glycosphingolipids (GSLs) have gained increased interest in the last few decades.
Caroline Mota Fernandes +2 more
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Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine
Phytotherapy Research, EarlyView.By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao +11 more
wiley +1 more source
Journal of Lipid Research, 1972 The glycosphingolipid composition of brain and visceral tissue from a patient with an unusual neurovisceral lipid storage disease, characterized by a lactosylceramide galactosyl hydrolase deficiency, was determined. Analyses of erythrocytes, plasma, bone
Glyn Dawson
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Glucosylceramide and the level of the glucosidase‐stimulating proteins [PDF]
, 1986 The concentration of β‐glucosidase‐stimulating proteins (called cohydrolase here) was measured in mouse liver and brain by immunoassay. Factors that might influence the levels of cohydrolase were examined.
Subhash C. Datta +3 more
core +1 more source
Journal of Lipid Research, 1976 A high performance liquid chromatographic (HPLC) method for analysis of galactosylceramides as their benzoyl derivatives has been devised. Samples containing 10-150 nmoles of monohexosylceramides are benzoylated by heating for 60 min at 60 ° C in 0.5 ml ...
E H McCluer, J E Evans
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Journal of Lipid Research, 2010 Shiga toxin (Stx)-producing Escherichia coli are the leading cause of hemorrhagic colitis and life-threatening extraintestinal complications in humans. Stx1 and Stx2 are transferred by yet to be delineated mechanisms from the intestine to the circulation
Christian H. Schweppe +7 more
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Metabolic Structure: A Paradigm Revisited in Light of the Fundamental Parameters of Living Systems
BioEssays, Volume 48, Issue 10, October 2026.Metabolism is redefined as a dynamic thermodynamic field shaped by six fundamental parameters (time, water, entropy, quantum effects, space, and electrostatics) rather than fixed genetic architecture. Case studies from enzyme kinetics to cancer cell differentiation show metabolic states, not structure alone, determine flux and control, and can be ...
Jacques Fantini
wiley +1 more source
Stimulation of liver growth and DNA synthesis by glucosylceramide [PDF]
, 1988 The nature of the growth‐stimulating effect of glucosylceramide was studied. Mice were injected intraperitoneally with emulsified glucosylceramide and conduritol B epoxide, an inhibitor of cerebroside glucosidase.
Datta, Subhash C., Radin, Norman S.
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