Results 51 to 60 of about 2,629 (119)
Non-hydroxylated galactosylceramide and glucosylceramide species in iPSC-derived astrocytes.
, 2022 (A) The profile of non-hydroxylated galactosylceramide species in control and Krabbe astrocytes suggests that shorter carbon chain length species are the predominant isoforms.
Hyejung Park (1322841) +8 more
core +1 more source
Glycosphingolipids from cultured astroblasts
Journal of Lipid Research, 1977 The glycolipids of two clonal lines astroblasts, NN clone and C6 clone, were studied. Glucosylceramide and lactosylceramide were present at very low levels in both clones, but the most common myelin glycolipids galactosylceramide and sulfatide, were not ...
J Robert, G Rebel, P Mandel
doaj +1 more source
European Journal of Immunology, Volume 56, Issue 10, October 2026.We present the first report of chicken lipid‐reactive, NKT‐like TCRVβ2+ T cells that recognize the endogenous ganglioside GM3 presented by chCD1.1 on live antigen‐presenting cells. This activation induces a rapid cytokine response from avian lipid‐reactive T cells, offering a universal target for lipid‐adjuvanted poultry vaccines.
Nitin Kamble +2 more
wiley +1 more source
eLife, 2013 Regulation of animal development in response to nutritional cues is an intensely studied problem related to disease and aging. While extensive studies indicated roles of the Target of Rapamycin (TOR) in sensing certain nutrients for controlling growth ...
Huanhu Zhu +4 more
doaj +1 more source
Clinical Experience With Eliglustat in Children With Gaucher Disease Type 1
American Journal of Medical Genetics Part A, EarlyView.
Erika R. Vucko +6 more
wiley +1 more source
Recycling pathways of glucosylceramide in BHK cells: distinct involvement of early and late endosomes [PDF]
, 1992 Recycling pathways of the sphingolipid glucosylceramide were studied by employing a fluorescent analog of glucosylceramide, 6(-)[N-(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoylglucosyl sphingosine (C6-NBD-glucosylceramide).
Hoekstra, Dick +3 more
core +7 more sources
β-Glucocerebrosidase activity in mammalian stratum corneum
Journal of Lipid Research, 1999 Although previous studies have demonstrated a crucial role for the enzyme β-glucocerebrosidase (GlcCer'ase) in the final steps of membrane structural maturation in mammalian stratum cornuem (SC) and epidermal homeostasis, the precise in vivo localization
Yutaka Takagi +4 more
doaj +1 more source
Pharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.ABSTRACT Purpose Gaucher disease (GD) requires lifelong high‐cost treatment within the Brazilian Unified Health System (SUS). In Brazil, treatment eligibility and monitoring are defined by Clinical Protocol and Therapeutic Guidelines (PCDT), while pharmaceutical prices are regulated by the Drug Market Regulation Chamber (CMED).
Marcus Carvalho Borin +4 more
wiley +1 more source
Frontiers in Pharmacology, 2019 Amyotrophic lateral sclerosis (ALS) is a multifactorial and fatal neurodegenerative disease. Growing evidence connects sphingolipid metabolism to the pathophysiology of ALS.
Alexandra Bouscary +12 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, Volume 600, Issue 17, Page 2526-2546, September 2026.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source