Molecules, 2018 To explore whether and how glucuronidation affects pyrogallol-type phytophenols, scutellarein and scutellarin (scutellarein-7-O-glucuronide) were comparatively investigated using a set of antioxidant analyses, including spectrophotometric analysis, UV ...
Qianru Liu +3 more
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Renal drug metabolism in humans: the potential for drug–endobiotic interactions involving cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT) [PDF]
, 2013 This item is under embargo for a period of 12 months from the date of publication, in accordance with the publisher's policy. ‘This is the peer reviewed version of the following article: Knights, K. M., Rowland, A. and Miners, J. O.
Knights, Kathleen Mary +2 more
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Aspects of UGT2B15 in the human [PDF]
, 2015 No abstract ...
Fowler, P.A., O'Shaughnessy, P.
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Effects of thyroid status and thyrostatic drugs on hepatic glucuronidation of lodothyronines and other substrates in rats - Induction of phenol UDP-glucuronyltransferase by methimazole [PDF]
, 1995 Glucuronidation of iodothyronines in rat liver is catalyzed by at least three UDP-glucuronyltransferases (UGTs): bilirubin UGT, phenol UGT, and androsterone UGT.
Bonthuis, F. (Fred) +6 more
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Developmental changes rather than repeated administration drive paracetamol glucuronidation in neonates and infants [PDF]
, 2015 Purpose: Based on recovered metabolite ratios in urine, it has been concluded that paracetamol glucuronidation may be up-regulated upon multiple dosing.
Allegaert, K.M. (Karel) +6 more
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Excretion of cholate glucuronide.
Journal of Lipid Research, 1985 [3-3H]Cholic acid glucuronide [7 alpha,12 alpha-dihydroxy-3 alpha-O-(beta-D-glucopyranosyluronate)-5 beta- cholan-24-oate] was synthesized and administered to rats prepared with either an external biliary fistula or a ligated bile duct. When bile fistula animals were given either microgram or milligram amounts of the glucuronide, biliary secretion of ...
Joanna M. Little, R Lester, M V Chari
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Clinical Pharmacology of Paracetamol in Neonates: A Review
Current Therapeutic Research, 2015 Paracetamol is commonly used to control mild-to-moderate pain or to reduce opioid exposure as part of multimodal analgesia, and is the only compound recommended to treat fever in neonates.
Gian Maria Pacifici, MD, PhD +1 more
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Gas Chromatography of Glucuronides.
Chemical and Pharmaceutical Bulletin, 1967 The applicability of gas chromatography to the analysis of various types of glucuronides including ether-, ester-, N-and S-glucuronides was studied by converting them to acetyl, methyl and trimethylsilyl derivatives.
Toshio Imanari, Zenzo Tamura
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Bidirectional interactions between indomethacin and the murine intestinal microbiota
eLife, 2015 The vertebrate gut microbiota have been implicated in the metabolism of xenobiotic compounds, motivating studies of microbe-driven metabolism of clinically important drugs.
Xue Liang +5 more
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The Evaluation of Genetic Profiles of UGT1A4 and UGT1A6 in the Turkish Population
Journal of Contemporary Medicine, 2021 Aim: Uridine diphosphate glucuronosyltransferases (UGTs) are a superfamily of conjugation phase II enzymes and is responsible for catalyzing the glucuronidation of many endobiotic or xenobiotic substrates.
Zuhal Uçkun Şahinoğulları
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