Results 141 to 150 of about 38,797 (256)
GLUT4 Interaction with Pre-existing Clusters.
, 2013 GLUT4-EOS association with (a) (see also Movie S5) and dissociation from (b) (see also Movie S6) pre-existing GLUT4 clusters. Activated GLUT4-EOS molecule, detected in the red channel, colocalizes with the cluster visible in green channel (non-activated ...
Vladimir A. Lizunov (387113) +4 more
core +1 more source
A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies
Traffic, Volume 27, Issue 3, September 2026.Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby +3 more
wiley +1 more source
Ready, set, internalize: mechanisms and regulation of GLUT4 endocytosis
, 2008 The facilitative glucose transporter GLUT4, a recycling membrane protein, is required for dietary glucose uptake into muscle and fat cells. GLUT4 is also responsible for the increased glucose uptake by myofibres during muscle contraction.
Michelangelo Foti +7 more
core +1 more source
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.ABSTRACT Background The serine/threonine kinase AKT is a key regulator of glucose and energy metabolism. Prevailing dogma suggests that AKT is an obligate intermediate for glucose uptake in all metabolic tissues and that impaired AKT signalling is a major molecular driver of insulin resistance in obesity.
Natasha Jaiswal +5 more
wiley +1 more source
Glut4 trafficking: Roles of LRP1, endosomal pH and Rab GTPases
, 2018 Insulin regulates Glut4 trafficking between the intracellular storage compartments and the PM of fat and muscle cells, which is a key process in glucose homeostasis.
Habtemichael, Estifanos N.
core
MicrobiologyOpen, Volume 15, Issue 4, August 2026.We conducted a cross‐sectional study involving three groups: OLP‐DM, OLP, and healthy controls. Salivary 16S rRNA sequencing and untargeted metabolomics revealed distinct microbial and metabolic profiles among groups, which were associated with disease severity.
Xiaomeng Ren +5 more
wiley +1 more source
Paper de l'Amino-Oxidasa Sensible a Semicarbazida, SSAO/VAP-1, del teixit adipós en la diabetis "mellitus" [PDF]
, 2003 [cat] L'SSAO/VAP-1 és una proteïna amb una dualitat de funció; d'una banda, presenta activitat enzimàtica amino-oxidasa i, de l'altra, presenta propietats d'adhesió que la impliquen en l'extravasació de limfòcits en processos inflamatoris.
Abella Martí, Anna
core
GIP in Cardiovascular and Kidney Disease: From Physiology to Pharmacology
Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6509-6532, August 2026.ABSTRACT Aims To provide a comprehensive overview of the cardiovascular and renal effects of glucose‐dependent insulinotropic polypeptide (GIP) by integrating its physiological role with recent human trial data on tirzepatide, the first dual GIP and glucagon‐like peptide‐1 (GLP‐1) receptor agonist.
Michelantonio De Fano +4 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 13, 15 July 2026.Simvastatin induces metabolic suppression, mitochondrial dysfunction, and atrophy‐related responses in skeletal muscle cells. In differentiated C2C12 myotubes, metformin partially attenuates these alterations by preserving myotube structural integrity, reducing cellular stress signaling, and maintaining mitochondrial network organization despite ...
Chuqi He +6 more
wiley +1 more source
Developmental Neurobiology, Volume 86, Issue 3, July 2026.ABSTRACT Lead is a toxic heavy metal with significant health risks, as maternal lead exposure during pregnancy disrupts fetal neural development through placental transfer, leading to persistent neurological, developmental, and long‐term health consequences in the progeny.
P. Harshitha +3 more
wiley +1 more source