Results 131 to 140 of about 38,797 (256)

Experiment 3, Drd1 and Glut4 protein level.

, 2013
Western blot and mean ± standard deviation of optical densities of soleus tissue that underwent the Vivo-morpholino cocktail treatment. Panel A represents four days post treatment of Drd1 and Glut4 expression comparing controls to Vivo-morpholino ...
David P. Ferguson (405112), Emily E. Schmitt (405113), J. Timothy Lightfoot (405114)   +2 more
core   +1 more source

Carbohydrate intake of 10 g/kg body mass rapidly replenishes liver, but not muscle glycogen contents, during 12 h of post‐exercise recovery in well‐trained cyclists

The Journal of Physiology, EarlyView.
Abstract figure legend Exhaustive cycling exercise substantially reduces liver and muscle glycogen stores. During 12 h of post‐exercise recovery without carbohydrate intake, glycogen stores remain depleted. In contrast, when carbohydrate is consumed at 10 g/kg body mass (BM), provided during the first 6 h as sucrose beverages (1.2 g/kg BM/h), liver ...
Cas J. Fuchs, Pandichelvam Veeraiah, Wesley J.H. Hermans, Bente Brauwers, Rick Voncken, Kim Brouwers, Heather L. Petrick, Floris K. Hendriks, Julia L.M. Bels, Job van den Hurk, Jil Weber, Joan M. Senden, Fiona E. Smith, Peter E. Thelwall, Jeanine J. Prompers, Luc J.C. van Loon   +15 more
wiley   +1 more source

GLUT4 localisation with the plasma membrane is unaffected by an increase in plasma free fatty acid availability

Lipids in Health and Disease
Background Insulin-stimulated glucose uptake into skeletal muscle occurs via translocation of GLUT4 from intracellular storage vesicles to the plasma membrane. Elevated free fatty acid (FFA) availability via a lipid infusion reduces glucose disposal, but
J. S. Barrett, J. A. Strauss, L. S. Chow, S. O. Shepherd, A. J. M. Wagenmakers, Y. Wang   +5 more
doaj   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Regulation of GLUT4 glucose transporter trafficking

, 2010
REGULATION OF GLUT4 GLUCOSE TRANSPORTER TRAFFICKING. Leah McNally and Jonathan Bogan, Departments of Internal Medicine and Cellular Biology, Yale University School of Medicine, New Haven CT.
McNally, Leah
core   +1 more source

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

Excessive training does not induce mitochondrial dysfunction or impair insulin signalling within skeletal muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Three weeks of overtraining in trained endurance athletes reduced exercise performance without impairing glucose tolerance. In skeletal muscle, overtraining was associated with increased expression of lipid metabolism‐related proteins, enhanced mitochondrial biogenesis and preserved insulin signalling, despite elevated oxidative ...
Geneviève J. DesOrmeaux, Henver S. Brunetta, Pierre‐Andre Barbeau, Alexandra M. Coates, Christopher Pignanelli, Fasih A. Rahman, Jamie F. Burr, Graham P. Holloway   +7 more
wiley   +1 more source

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

The Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos, Martin Olmos, Courtney P. Wood, Camila Alvarez, Haley M. Read, Parima Udompholkul, Theodore Garland Jr, Nicholas V. DiPatrizio   +7 more
wiley   +1 more source

Fasting‐induced glucose intolerance is not impacted by the addition of daily exercise: A randomized crossover study

The Journal of Physiology, EarlyView.
Abstract figure legend In a randomized crossover design 16 healthy young adults performed a 48‐h fast with or without the addition of daily cycling (50‐min moderate‐intensity continuous training (MICT) + 5×1‐min high‐intensity interval training (HIIT)) at baseline and 24 h into the fast.
Tori Bouck, Alexis Marcotte‐Chénard, Darren Barg, Charlie Kanuka, Roderick E. Sandilands, Spencer Ursel, Garett Jackson, Arwyn MacIntosh, Sean McIntyre, Sriyashika Nekkanti, Kimberly Day, Hashim Islam, Jonathan P. Little   +12 more
wiley   +1 more source

Fish and mammalian glut4 traffic characteristics: an evolutionary perspective on the importance of glut4 protein motifs for trafficking [PDF]

, 2018
Glucose transporters (GLUTs) are extremely important for glucose metabolism. Glucose transporters uptake glucose from blood stream into the cells where it can be metabolized.
Carvalho Simoes, Francisco Manuel de
core