Results 91 to 100 of about 3,983 (152)

Immunoreactivity of urate transporters, GLUT9 and URAT1, is located in epithelial cells of the choroid plexus of human brains

It has been suggested that urate plays a protective role in neurons, while hyperuricemia is correlated with atherosclerosis and cardiovascular disease.
Uemura, Naoya, 植村, 直哉, ウエムラ, ナオヤ   +2 more
core  

Piperine Improves Hyperuricemic Nephropathy by Inhibiting URAT1/GLUT9 and the AKT-mTOR Pathway

Uncontrolled hyperuricemia often leads to the development of hyperuricemic nephropathy (HN), characterized by excessive inflammation and oxidative stress.
Heyang Jiang (18176357), Yongmei Li (227480), Ting Wu (106368), Jinhong Tian (15451914), Zean Zhao (9309695), Kunlu Zhao (18176351), Jianxin Pang (6596942), Lu Li (14069), Xueman Lin (18176354), Jian Luo (133137), Fengxin Zheng (18153963), Zijun Xie (396840)   +11 more
core   +1 more source

6'‑O‑Caffeoylarbutin attenuates experimental hyperuricemia by regulating renal and intestinal urate transport, intestinal barrier integrity, and gut microbiota. [PDF]

Mol Med Rep
Yu X, Zhang Y, Sun K, Yang R, Li X, Chen X, Li T, Yang X, Li M, Liu L, Li F, Shen B.   +11 more
europepmc   +1 more source

Therapeutic potential of traditional Chinese medicine for hyperuricemia: mechanistic insights and clinical prospects. [PDF]

Front Pharmacol
Li H, You S, Luo X, Huang Y, Li M, Zhou J, Ren S.   +6 more
europepmc   +1 more source

<i>Brassica rapa</i> L. (Turnip) Ethanol Extract Alleviates Hyperuricemia by Modulating Purine Metabolism Enzymes and Renal Urate Transporters. [PDF]

Foods
Wang Y, Yang Y, Liu Y, Cheng D, Yao W, Yusuf A, Yang K.   +6 more
europepmc   +1 more source

Gut microbiota and uric acid excretion signaling in pathogenesis of hyperuricemia and acute gouty arthritis. [PDF]

iScience
Wang M, Yang R, An H, Chen B, Chen Q, Chen Z, Li M, Yang F, Xiao Y, Chen P, Guo J, Su Y, Huang B.   +12 more
europepmc   +1 more source

GLUT9b- and ABCG2-mediated collecting duct urate transport uncovers a vasopressin-independent mechanism of renal water reabsorption. [PDF]

J Clin Invest
Hadla M, Mardirossian JM, Bichet DG, Borghol AH, Abboud G, Ghanem A, Chini E, Harris P, Torres VE, Alper SL, Vallon V, Chebib FT.   +11 more
europepmc   +1 more source

Saponins Derived from Chinese Medicinal Materials in Hyperuricemia and Gout: Therapeutic Mechanisms and Emerging Perspectives. [PDF]

Molecules
Wang Z, Chen Y, Li T, Hu Y, Li L.
europepmc   +1 more source

Structural characterization of a novel low-molecular-weight β-fructan from <i>Panax quinquefolius</i> and its effect on ameliorating hyperuricemia. [PDF]

J Ginseng Res
Yu J, Wang C, Jiang M, Li T, Guo Y, Zhong K, Zhao L, Wang X.   +7 more
europepmc   +1 more source

Comprehensive phytochemical profiling of dealcoholized zhuyeqing liquor extract and its protective effect on hyperuricemia by regulating urate transporters and LPS/NLRP3 inflammasome pathway. [PDF]

Front Nutr
Xu B, Li X, Liu R, Han Y, Zhen P, Fu H, Lv H, Wei F, Cui H, Zhang B, Wang S.   +10 more
europepmc   +1 more source