Results 31 to 40 of about 41,955 (229)

Glutathione Metabolism in Renal Cell Carcinoma Progression and Implications for Therapies [PDF]

, 2019
A significantly increased level of the reactive oxygen species (ROS) scavenger glutathione (GSH) has been identified as a hallmark of renal cell carcinoma (RCC). The proposed mechanism for increased GSH levels is to counteract damaging ROS to sustain the
Meierhofer, David, Xiao, Yi
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Adaptation to G93A superoxide dismutase 1 in a motor neuron cell line model of amyotrophic lateral sclerosis. The role of glutathione [PDF]

, 2009
Motor neuron degeneration in amyotrophic lateral sclerosis involves oxidative damage. Glutathione (GSH) is critical as an antioxidant and a redox modulator.
AND LAVINIA CANTONI, D'ALESSANDRO, GIUSEPPINA, ELISABETTA BABETTO, LAURA CONFORTI, MILENA RIZZARDINI, SILVIA TARTARI   +5 more
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Green tea polyphenol (-)-epigallocatechin-3-gallate restores Nrf2 activity and ameliorates crescentic glomerulonephritis. [PDF]

PLoS ONE, 2015
Crescentic glomerulonephritis (GN) is the most severe form of GN and is associated with significant morbidity and mortality despite aggressive immunotherapy with steroids, cytotoxic drugs, and plasmapheresis.
Ting Ye, Junhui Zhen, Yong Du, Jason K Zhou, Ai Peng, Nosratola D Vaziri, Chandra Mohan, Yan Xu, Xin J Zhou   +8 more
doaj   +1 more source

The effects of magnolol supplementation on growth performance, meat quality, oxidative capacity, and intestinal microbiota in broilers

Poultry Science, 2022
: The aim of the present study was to evaluate the effect of magnolol (MAG) on growth performance, meat quality, oxidative capacity, and intestinal microbiota in the yellow-feather broilers.
Qian Xie, Kaihuan Xie, Jinhui Yi, Zehe Song, Haihan Zhang, Xi He   +5 more
doaj   +1 more source

Molecular responses of mouse macrophages to copper and copper oxide nanoparticles inferred from proteomic analyses [PDF]

, 2013
The molecular responses of macrophages to copper-based nanoparticles have been investigated via a combination of proteomic and biochemical approaches, using the RAW264.7 cell line as a model.
Aude-Garcia, Catherine, Carrière, Marie, Chevallet, Mireille, Collin-Faure, Véronique, Diemer, Hélène, Habert, Aurélie, Hanau, Daniel, Herlin-Boime, Nathalie, Proamer, Fabienne, Rabilloud, Thierry, Strub, Jean-Marc, Triboulet, Sarah, Van Dorsselaer, Alain   +12 more
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Adipocytes cause leukemia cell resistance to daunorubicin via oxidative stress response. [PDF]

, 2016
Adipocytes promote cancer progression and impair treatment, and have been shown to protect acute lymphoblastic leukemia (ALL) cells from chemotherapies. Here we investigate whether this protection is mediated by changes in oxidative stress.
Behan, James W, Heisterkamp, Nora, Ji, Lingyun, Mittelman, Steven D, Parmentier, Jean-Hugues, Sheng, Xia, Tucci, Jonathan   +6 more
core   +1 more source

The Effects of Cocaine on Different Redox Forms of Cysteine and Homocysteine, and on Labile, Reduced Sulfur in the Rat Plasma Following Active versus Passive Drug Injections [PDF]

, 2013
Received: 28 November 2012 / Revised: 19 April 2013 / Accepted: 6 May 2013 / Published online: 16 May 2013 The Author(s) 2013. This article is published with open access at Springerlink.comThe aim of the present studies was to evaluate cocaine ...
A Madayag, A Meister, AA Tambe, AJ Cooper, CQ Chen, DA Baker, DA Baker, Danuta Kowalczyk-Pachel, DC Carter, DP Jones, E Bald, E Bald, Elżbieta Lorenc-Koci, G Chwatko, G Lund, GJ McBean, GJ McBean, Grażyna Chwatko, H Refsum, H Sato, H Turhan, HJ Forman, HJ Forman, HL Wiener, I Barutcu, I Dalle-Donne, I Dalle-Donne, JB Dietrich, JD Uys, JE Schnitzer, JI Toohey, JJ Mieyal, JM Mato, Joanna Czyżyk, K Fijał, KM Humphries, KS Kau, KS McCully, L Pomierny-Chamioło, L Włodek, LH Lash, Lidia Włodek, M Conrad, M Iciek, M Kemp, M Muriach, MA Evans, Małgorzata Filip, Małgorzata Iciek, NL Reynaert, O Stanger, P Klatt, P Kovacic, PN Mardikian, PW Beatty, PW Kalivas, R Banerjee, R Castro, R Labib, R Labib, RA Kloner, RC Twining, S Githens, S Kandil, S Sengupta, S Zaina, SA Everett, SC Lu, SD LaRowe, SE Hyman, SH Rezkalla, SL Amen, SZ Mehanny, T Fiaschi, T Visalli, V Vitvitsky, W Tian, W Zhou, YI Kim, YM Go, YM Kupchik   +80 more
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Glutathione s-transferase omega in the lung and sputum supernatants of COPD patients [PDF]

, 2015
BACKGROUND: The major contribution to oxidant related lung damage in COPD is from the oxidant/antioxidant imbalance and possibly impaired antioxidant defence. Glutathione (GSH) is one of the most important antioxidants in human lung and lung secretions,
Board, Philip, Harju, Terttu H, Kinnula, Vuokko L, Peltoniemi, Mirva J, Ruddock, Lloyd W, Rytila, Paula H, Salmenkivi, Kaisa M, Soini, Ylermi   +7 more
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Overexpression of Glutamate-Cysteine Ligase Extends Life Span in Drosophila melanogaster [PDF]

Journal of Biological Chemistry, 2005
The hypothesis that overexpression of glutamate-cysteine ligase (GCL), which catalyzes the rate-limiting reaction in de novo glutathione biosynthesis, could extend life span was tested in the fruit fly, Drosophila melanogaster. The GAL4-UAS binary transgenic system was used to generate flies overexpressing either the catalytic (GCLc) or modulatory ...
William C, Orr, Svetlana N, Radyuk, Leena, Prabhudesai, Dikran, Toroser, Judith J, Benes, James M, Luchak, Robin J, Mockett, Igor, Rebrin, J Gregory, Hubbard, Rajindar S, Sohal   +9 more
openaire   +2 more sources

Environmental toxicity, redox signaling and lung inflammation:the role of glutathione [PDF]

, 2009
Glutathione (γ-glutamyl-cysteinyl-glycine, GSH) is the most abundant intracellular antioxidant thiol and is central to redox defense during oxidative stress.
Antonicelli, Aoki, Arfsten, Aruoma, Asti, Ault, Azzi, Bakin, Banhegyi, Banhegyi, Beck, Beeh, Beeh, Bindoli, Biswas, Borgstrom, Braga, Bridgeman, Bunnell, Burgunder, Butterworth, Cantin, Chakravarthi, Chan, Chan, Chen, Chen, Chuang, Church, Colombo, Cotgreave, Cotgreave, Crouch, Crystal, Das, De Benedetto, de Boer, De Caro, Decramer, Decramer, Dekhuijzen, Deleve, Dickinson, Dinkova-Kostova, Drost, Dueholm, Ekberg-Jansson, Erickson, Forman, Galloway, Gerrits, Gillissen, Grandjean, Grigg, Guidot, Haddad, Halliwell, Harju, Harper, Hayes, He, Holdiness, Huang, Hwang, Inci, Irfan Rahman, Ishibashi, Itoh, Janssen, Jardine, Jessop, Jeyapaul, Kang, Kasielski, Katayama, Kidd, Kim, Kinnula, Kinnula, Kinnula, Kinnula, Kobayashi, Kode, Koike, Komatsu, Krzywanski, Kwong, Lee, Lee, Lee, Leonard, Liu, Liu, Lomaestro, Lowry, Lu, Luppi, Mattes, McKone, Meister, Meyer, Miao, Monova, Moran, Moretti, Moretti, Mulcahy, Nakayama, Pacht, Paget, Park, Parmentier, Peltoniemi, Pietarinen-Runtti, Pinkus, Poole, Poole, Rahman, Rahman, Rahman, Rahman, Rahman, Rahman, Rahman, Rahman, Rasmusse, Reddy, Reynaert, Rhee, Roum, Rutkowski, Sadowska, Saibal K. Biswas, Shi, Shin, Siedlinski, Singh, Smith, Stey, Suter, Tanaka, Tian, Tirouvanziam, Tomonari, Trachootham, Tsikas, Tu, Usatyuk, Valko, van der Toorn, Van Schooten, Wakabayashi, Wang, White, Wild, Wood, Wood, Yang, Yang, Yang, Yeh, Zhang, Zhang   +162 more
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