Results 51 to 60 of about 808,650 (427)
Frontiers in Immunology, 2020 Breastfeeding is indicated to support neonatal immune development and to protect against neonatal infections and allergies. Human milk composition is widely studied in relation to these unique abilities, which has led to the identification of various ...
Joris H. J. van Sadelhoff +4 more
doaj +1 more source
Stability, affinity and chromatic variants of the glutamate sensor iGluSnFR
Nature Methods, 2018 Single-wavelength fluorescent reporters allow visualization of specific neurotransmitters with high spatial and temporal resolution. We report variants of intensity-based glutamate-sensing fluorescent reporter (iGluSnFR) that are functionally brighter ...
J. Marvin +21 more
semanticscholar +1 more source
CRF1/CRF2 and MC3/MC4 Receptors Affect Glutamate- Induced Food Intake in Neonatal Meat-Type Chicken
Brazilian Journal of Poultry Science, 2019 Central glutamate, melanocortin and corticotropin systems have mediatory role on several physiologic functions in the brain, but their interactions on appetite regulation are not fully elicited.
F Ahmadi +3 more
doaj +1 more source
Frontiers in Pediatrics, 2021 Background: Amino acids are increasingly recognized as bioactive molecules in numerous physiological and pathophysiological pathways. The non-essential amino acid glutamate is vasoactive in the rat ductus arteriosus (DA) and a decrease in its levels ...
Maurice J. Huizing +9 more
doaj +1 more source
Energy metabolism and glutamate-glutamine cycle in the brain: a stoichiometric modeling perspective [PDF]
BMC Systems Biology 7:103 (2013), 2013 The energetics of cerebral activity critically relies on the functional and metabolic interactions between neurons and astrocytes. Important open questions include the relation between neuronal versus astrocytic energy demand, glucose uptake and intercellular lactate transfer, as well as their dependence on the level of activity.
arxiv +1 more source
Metabotropic glutamate receptors: physiology, pharmacology, and disease.
Annual Review of Pharmacology and Toxicology, 2010 The metabotropic glutamate receptors (mGluRs) are family C G-protein-coupled receptors that participate in the modulation of synaptic transmission and neuronal excitability throughout the central nervous system.
C. Niswender, P. Conn
semanticscholar +1 more source
Cortical glutamate in migraine [PDF]
Brain, 2017 Cortical hyperexcitability due to enhanced glutamatergic activity has been implicated in migraine pathophysiology but direct evidence is lacking. Here we assessed glutamate levels and intracellular mobility of glutamate in the visual cortex of migraineurs in-between attacks.
Mark C. Kruit +9 more
openaire +5 more sources
Frontiers in Psychiatry, 2020 Amino acid neurotransmitters have been shown to correlate with Tourette syndrome (TS) and its comorbidities. In this study, we investigated the effects of Jian-Pi-Zhi-Dong Decoction (JPZDD), a formula containing 10 different Chinese medical herbs, on ...
Wen Zhang +6 more
doaj +1 more source
Protective effect of naringenin on glutamate-induced neurotoxicity in cultured hippocampal cells [PDF]
Archives of Biological Sciences, 2015 Monosodium glutamate induces excitotoxicity in the central nervous system through hyperactivation of both ionotropic and metabotropic glutamate receptors, which leads to neuronal cell death.
Xu Xiao-Hui +8 more
doaj +1 more source
Potential protective roles of phytochemicals on glutamate-induced neurotoxicity: A review [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Glutamate, as an essential neurotransmitter, has been thought to have different roles in the central nervous system (CNS), including nerve regeneration, synaptogenesis, and neurogenesis.
Amir R. Afshari +5 more
doaj +1 more source