Results 61 to 70 of about 808,650 (427)

Glutamate Receptor [PDF]

open access: yes, 2016
[No abstract]
openaire   +2 more sources

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

open access: yesFEBS Letters, EarlyView.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

Pharmacogenetics of SSRIs and Sexual Dysfunction

open access: yesPharmaceuticals, 2010
Sexual dysfunction (SD) is a common and disconcerting side effect of selective serotonin reuptake inhibitors (SSRIs) that often influences a patient’s desire to continue long-term antidepressant treatment. Studies specifically assessing changes in sexual
Liana Osis, Jeffrey R. Bishop
doaj   +1 more source

Probing Scalar Coupling Differences via Long-Lived Singlet States [PDF]

open access: yes, 2015
We probe small scalar coupling differences via the coherent interactions between two nuclear spin singlet states in organic molecules. We show that the spin-lock induced crossing (SLIC) technique enables the coherent transfer of singlet order between one spin pair and another.
arxiv   +1 more source

In Vivo Magnetic Resonance Spectroscopy by J-Locked Chemical Shift Encoding for Determination of Neurochemical Concentration and Transverse Relaxation Time [PDF]

open access: yesarXiv, 2023
Cell pathology in neuropsychiatric disorders has mainly been accessible by analyzing postmortem tissue samples. Although molecular transverse relaxation informs local cellular microenvironment via molecule-environment interactions, precise determination of the transverse relaxation times of molecules with scalar couplings (J), such as glutamate and ...
arxiv  

Ornithine-catalyzed urea formation in liver homogenate [PDF]

open access: yes, 1947
Heretofore attempts to obtain synthesis of urea from ammonia (and carbon dioxide) in cell-free extracts have been unsuccessful. We have found the reaction to proceed in guinea pig liver homogenate.
Borsook, Henry, Dubnoff, Jacob W.
core  

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Heat-Bath Cooling of Spins in Two Amino Acids [PDF]

open access: yesChem. Phys. Lett. 517, 126-131 (2011), 2011
Heat-bath cooling is a component of practicable algorithmic cooling of spins, an approach which might be useful for in vivo 13C spectroscopy, in particular for prolonged metabolic processes where substrates that are hyperpolarized ex-vivo are not effective.
arxiv   +1 more source

Surface Grafting of Poly(L-glutamates). 2. Helix Orientation [PDF]

open access: yes, 2001
In this paper the average helix orientation of surface-grafted poly(γ-benzyl L-glutamate) (PBLG), poly(γ-methyl L-glutamate) (PMLG), and poly(γ-methyl L-glutamate)-co-(γ-n-stearyl L-glutamate) (PMLGSLG 70/30) was investigated by means of FT-IR ...
Arndt T.   +29 more
core   +3 more sources

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