Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors. [PDF]
Jean‐Philippe Pin+3 more
openalex +1 more source
This study proposes a two‐step biological strategy to synergistically enhance the three stages of anaerobic digestion, ultimately eliminating the extreme ammonia inhibition and breaking through the inefficiency bottleneck of conventional biotechnology.
Heng Wu+6 more
wiley +1 more source
Interactions between the glycine and glutamate binding sites of the NMDA receptor [PDF]
R.A.J. Lester, Gang Tong, CE Jahr
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Designed Biomaterial‐Enhanced Cell Transplantation for Neural Tissue Engineering
Biomaterials offer a promising solution for cell transplantation in the central nervous system by creating a protective environment that enhances cell survival, integration, and functional recovery in preclinical models of neurological disorders. ABSTRACT Cell transplantation therapy in the central nervous system is hindered by limited survival and ...
Yun Tang+3 more
wiley +1 more source
Homo- and hetero-dimeric subunit interactions set affinity and efficacy in metabotropic glutamate receptors. [PDF]
Habrian C+3 more
europepmc +1 more source
Inducible expression of neuronal glutamate receptor channels in the NT2 human cell line.
Donald Younkin+7 more
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Abstract INTRODUCTION Human tau protein, composed of six brain‐specific isoforms, is a major driver of Alzheimer's disease (AD). The role of its isoforms however remains unclear and human AD models are scarce. METHODS We generated human MAPT– (tau–) knockout (KO) induced pluripotent stem cells (iPSC) using CRISPR/Cas9, differentiated these into ...
Sarah Buchholz+11 more
wiley +1 more source
Challenges in Elucidating the Free Energy Scheme of the Laccase Catalyzed Reduction of Oxygen
Bioinorganic chemistry: High potential variants of the multicopper enzyme laccase have a remarkably low overpotential for the oxygen reduction reaction (ORR). Understanding the precise underlying principles are potentially of great value in light of the energy transition wherein the ORR plays a crucial role.
Daan den Boer+3 more
wiley +1 more source
Kinetic fingerprinting of metabotropic glutamate receptors. [PDF]
Kukaj T+4 more
europepmc +1 more source
Modulation of calcium currents by a metabotropic glutamate receptor involves fast and slow kinetic components in cultured hippocampal neurons [PDF]
Yoshinori Sahara, GL Westbrook
openalex +1 more source