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Congenital Glutamine Deficiency with Glutamine Synthetase Mutations [PDF]

New England Journal of Medicine, 2006
Rose, Christopher, Jalan, Rajiv
openaire   +4 more sources

Production of Corn Protein Hydrolysate with Glutamine-Rich Peptides and Its Antagonistic Function in Ulcerative Colitis In Vivo

Foods, 2022
Ulcerative colitis is a typical chronic inflammatory disease of the gastrointestinal tract, which has become a serious hazard to human health. The purpose of the present study was to evaluate the antagonistic effect of corn protein hydrolysate with ...
Yan Jing, Xiaolan Liu, Jinyu Wang, Yongqiang Ma, Xiqun Zheng   +4 more
doaj   +1 more source

Gene expression profiling indicates a shift in ammonia assimilation capacity along the hepatic acinus induced by different forms of selenium in vitamin–mineral mixes fed to beef steers grazing on toxic endophyte-infected tall fescue

Frontiers in Animal Science, 2023
Recently, we demonstrated that supplementing (with 3 mg Se per day) the diets of growing beef steers grazing on Se-deficient toxic endophyte-infected tall fescue-based forage with either organic Se (OSe, SEL-PLEX) or a 1:1 blend (MIX) of OSe and ...
Yang Jia, Kwangwon Son, James C. Matthews   +2 more
doaj   +1 more source

Macropinocytosis mediates resistance to loss of glutamine transport in triple-negative breast cancer

The EMBO Journal
Triple-negative breast cancer (TNBC) metabolism and cell growth uniquely rely on glutamine uptake by the transporter ASCT2. Despite previous data reporting cell growth inhibition after ASCT2 knockdown, we here show that ASCT2 CRISPR knockout is tolerated
Kanu Wahi, Natasha Freidman, Qian Wang, Michelle Devadason, Lake-Ee Quek, Angel Pang, Larissa Lloyd, Mark Larance, Fabio Zanini, Kate Harvey, Sandra O’Toole, Yi Fang Guan, Jeff Holst   +12 more
doaj   +1 more source

The Human SLC1A5 Neutral Amino Acid Transporter Catalyzes a pH-Dependent Glutamate/Glutamine Antiport, as Well

Frontiers in Cell and Developmental Biology, 2020
ASCT2 is a neutral amino acid transporter, which catalyzes a sodium-dependent obligatory antiport among glutamine and other neutral amino acids. The human ASCT2 over-expressed in Pichia pastoris and reconstituted in proteoliposomes has been employed for ...
Mariafrancesca Scalise, Tiziano Mazza, Gilda Pappacoda, Lorena Pochini, Jessica Cosco, Filomena Rovella, Cesare Indiveri, Cesare Indiveri   +7 more
doaj   +1 more source

A Metabolomic Approach to Unexplained Syncope

Biomedicines
Background: This study aims to identify a metabolomic signature that facilitates the classification of syncope and the categorization of the unexplained syncope (US) to aid in its management.
Susanna Longo, Ilaria Cicalini, Damiana Pieragostino, Vincenzo De Laurenzi, Jacopo M. Legramante, Rossella Menghini, Stefano Rizza, Massimo Federici   +7 more
doaj   +1 more source

Efeito da glutamina sobre o turnover do carbono (d13C) de músculos e vísceras de leitões desmamados: glutamina e turnover de carbono tecidual = Effect of glutamine on carbon (d13C) turnover in the muscles and viscera of weaned piglets

Acta Scientiarum: Animal Sciences, 2008
O estudo foi conduzido para verificar a influência da glutamina no turnover do carbono em tecidos de leitões. Nove porcas foram cobertas e receberam dietas compostas predominantemente por grãos de plantas do ciclo fotossintético C4 durante gestação e ...
Fabiana Ribeiro Caldara, Carlos Ducatti, Dirlei Antonio Berto, Juliana Célia Denadai, Evandro Tadeu da Silva, Rodrigo Garófallo Garcia   +5 more
doaj  

Effect of Oral Glutamine on Patient Outcomes following Open Heart Surgery: A Double Blind Clinical Trial

Journal of Mazandaran University of Medical Sciences, 2019
Background and purpose: Cardiovascular diseases are the most common cause of death worldwide. Surgical treatment is one of the main treatment options for cardiac diseases.
Gohar Eslami, Rahman Ghafari, Valiollah Habibi, Aria Soleimani, Jamshid Yazdani Charati, Hasti Sadraei, Shahaboddin Emami, Majid Javanmard   +7 more
doaj  

Supplementation of L-glutamine enhanced mucosal immunity and improved hormonal status of combat-sport athletes

Journal of the International Society of Sports Nutrition
Background Maintaining proper immune function and hormone status is important for athletes to avoid upper respiratory tract infection (URTI) and insufficient recovery, which is detrimental to sport performance and health.
Tung-Lin Lu, Ai-Chi Zheng, Katsuhiko Suzuki, Chi-Cheng Lu, Chung-Yuan Wang, Shih-Hua Fang   +5 more
doaj   +1 more source

Chronic Hypoxia Enhances β-Oxidation-Dependent Electron Transport via Electron Transferring Flavoproteins

Cells, 2019
Hypoxia poses a stress to cells and decreases mitochondrial respiration, in part by electron transport chain (ETC) complex reorganization. While metabolism under acute hypoxia is well characterized, alterations under chronic hypoxia largely remain ...
Dominik C. Fuhrmann, Catherine Olesch, Nina Kurrle, Frank Schnütgen, Sven Zukunft, Ingrid Fleming, Bernhard Brüne   +6 more
doaj   +1 more source