Results 61 to 70 of about 760,519 (335)
Frontiers in Nutrition, 2023 It is widely known that most cancer cells display an increased reliance on glutaminolysis to sustain proliferation and survival. Combining glutamine deprivation with additional anti-cancer therapies is an intensively investigated approach to increase ...
Florian Lengauer +5 more
doaj +1 more source
Effects of in vitro potassium on ammoniagenesis in rat and canine kidney tissue [PDF]
, 1912 Effects of in vitro potassium on ammoniagenesis in rat and canine kidney tissue. Decreased ammonium (NH4+) excretion is associated with hyperkalemia.
Raymond S. Sleeper +60 more
core +1 more source
Mitochondrial fatty acid oxidation is stimulated by red light irradiation
FEBS Letters, EarlyView.Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera +4 more
wiley +1 more source
Glutamine: A novel approach to chemotherapy-induced toxicity
Indian Journal of Medical and Paediatric Oncology, 2012 Treatment of cancer is associated with short- and long-term side-effects. Cancer produces a state of glutamine deficiency, which is further aggravated by toxic effects of chemotherapeutic agents leading to increased tolerance of tumor to chemotherapy as ...
Kumar Gaurav +3 more
doaj +1 more source
Glutamine supplementation to prevent morbidity and mortality in preterm infants [PDF]
, 2016 BACKGROUND: Glutamine is a conditionally essential amino acid. Endogenous biosynthesis may be insufficient for tissue needs in states of metabolic stress. Evidence exists that glutamine supplementation improves clinical outcomes in critically ill adults.
Brown, Jennifer Ve +2 more
core +1 more source
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Nucleic Acid Metabolism in Patients with Severe Burn Injury and the Possibility of Its Correction
Общая реаниматология, 2019 Purpose. To assess changes in nucleic acid (NA) metabolism in severe burn injury and to develop recommendations for correction of the alimentary status taking into account changes in the NA metabolism. Materials and methods.
E. I. Vereshchagin +6 more
doaj +1 more source
Glutamine as an Immunonutrient
Yonsei Medical Journal, 2011 Dietary supplementation with nutrients enhancing immune function is beneficial in patients with surgical and critical illness. Malnutrition and immune dysfunction are common features in hospitalized patients. Specific nutrients with immunological and pharmacological effects, when consumed in amounts above the daily requirement, are referred to as ...
openaire +2 more sources
Distinct amino acid compositional requirements for formation and maintenance of the [PSI+] prion in yeast [PDF]
, 2015 Multiple yeast prions have been identified that result from the structural conversion of proteins into a self-propagating amyloid form. Amyloid-based prion activity in yeast requires a series of discrete steps.
Ben-Musa, Zobaida +6 more
core +2 more sources
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source