Results 31 to 40 of about 1,091,861 (290)
Cell Communication and Signaling, 2022 Metabolic reprogramming and immune escape play a major role in tumorigenesis. Increasing number of studies have shown that reprogramming of glutamine metabolism is a putative determinant of the anti-tumor immune response in the tumor microenvironment ...
Guofeng Ma +10 more
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Cell Death and Disease, 2023 Anaplastic thyroid cancer (ATC) is one of the most aggressive tumors with an extremely poor prognosis. Based on the several biological features related to glutamine metabolism in ATC, we hypothesized glutaminolysis inhibition induces cell death in ATC ...
Yeseong Hwang +8 more
doaj +1 more source
GLUTAMINE METABOLISM OF THE BEET [PDF]
Plant Physiology, 1936 Although glutamine has long been known as a plant constituent (10), the relationship of this amide to the nitrogen metabolism of the plant has seldom been subjected to direct test. The close analogy in chemical structure with asparagine and the similarity of the conditions under which the respective amides are found have led to the view, early ...
H B, Vickery, G W, Pucher, H E, Clark
openaire +2 more sources
Glutamine Metabolism Supports the Functional Activity of Immune Cells against Aspergillus fumigatus
Microbiology Spectrum, 2023 The reprogramming of cellular metabolism of immune cells is an essential process in the regulation of antifungal immune responses. In particular, glucose metabolism has been shown to be required for protective immunity against infection with Aspergillus ...
Daniela Antunes +16 more
doaj +1 more source
Take Advantage of Glutamine Anaplerosis, the Kernel of the Metabolic Rewiring in Malignant Gliomas
Biomolecules, 2020 Glutamine is a non-essential amino acid that plays a key role in the metabolism of proliferating cells including neoplastic cells. In the central nervous system (CNS), glutamine metabolism is particularly relevant, because the glutamine-glutamate cycle ...
Filipa Martins +3 more
doaj +1 more source
Scientific Reports, 2022 Glutamine provides carbon and nitrogen for macromolecular synthesis and participates in adenosine triphosphate (ATP) generation, anabolic metabolism, redox homeostasis, cell signaling, and cancer stem cell (CSC) metabolism.
Yoojeong Seo +3 more
doaj +1 more source
Hormone-Glutamine Metabolism: A Critical Regulatory Axis in Endocrine-Related Cancers
, 2022 The endocrine-related cancers and hormones are undoubtedly highly interconnected. How hormones support or repress tumor induction and progression has been extensively profiled.
Li, Mingqing +15 more
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Metabolic responses of primary and transformed cells to intracellular Listeria monocytogenes. [PDF]
, 2012 The metabolic response of host cells, in particular of primary mammalian cells, to bacterial infections is poorly understood. Here, we compare the carbon metabolism of primary mouse macrophages and of established J774A.1 cells upon Listeria monocytogenes
Wolfgang Eisenreich (108576) +14 more
core +1 more source
Glutamine in critical care:current evidence from systematic reviews [PDF]
, 2006 Glutamine, the most abundant amino acid in the body, is thought to become conditionally essential in critical illness. Some of the important roles for glutamine are as a carrier for inter-organ N, a preferred fuel for enterocytes and cells of the immune ...
Avenell, Alison
core +1 more source
Cells, 2022 Glutamine metabolism is critical both for the proliferation of cancer cells and the activation of CD8T cells to kill cancer cells. We aim to explore the relationship between the glutamine metabolism of CD8T cells and cancer cells and tumor immunity in ...
Jianfei Chen +8 more
doaj +1 more source