Results 91 to 100 of about 9,840 (178)

Serial Spatial Transcriptomes Reveal Regulatory Transitions in Maize Leaf Development

Plant Biotechnology Journal, Volume 24, Issue 5, Page 2787-2810, May 2026.
ABSTRACT Plant leaves originate from the shoot apical meristem (SAM) and undergo a developmental process of highly coordinated gene expression regulation. To date, only a few key regulators have been identified and characterised, so the gene expression cascades responsible for leaf cell specification and differentiation from SAM remain largely elusive.
Chi‐Chih Wu, Ludvig Larsson, Kun‐Ting Hsieh, Chun‐Ping Yu, Yi‐Hua Chen, Kai‐Hsuan Ding, Ho‐Chun Yang, Joakim Lundeberg, Chin‐Min Kimmy Ho, Shu‐Hsing Wu, Mei‐Yeh Jade Lu, Wen‐Hsiung Li   +11 more
wiley   +1 more source

Glutaredoxin-1 up-regulation induces soluble vascular endothelial growth factor receptor 1, attenuating post-ischemia limb revascularization [PDF]

, 2014
Glutaredoxin-1 (Glrx) is a cytosolic enzyme that regulates diverse cellular function by removal of GSH adducts from S-glutathionylated proteins including signaling molecules and transcription factors. Glrx is up-regulated during inflammation and diabetes.
Ho, Ye-Shih, Matsui, Reiko, Murdoch, Colin E., Murdoch, Colin E.; id_orcid, Shuler, Michaela, Haeussler, Dagmar J.F., Kikuchi, Ryosuke, Han, Jingyan, Watanabe, Yosuke, Bearelly, Priyanka, Walsh, Kenneth, Bachschmid, Markus M., Fuster, José J., Cohen, Richard A.   +13 more
core   +1 more source

Stress Granule‐Associated ZmCTU2 Confers Thermotolerance in Maize via Coordinated Regulation of Proteostasis and ROS Homeostasis

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3371-3390, May 2026.
ABSTRACT The escalating global temperatures and intensifying heat stress events pose significant threats to maize productivity worldwide. Uncovering key thermotolerance genes and their functional mechanisms is thus critical for developing climate‐resilient crops.
Yufang Xu, Yudong Fan, Yulian Li, Yilin Zhang, Enpeng Liu, Ruiqi Li, Peipei Ma, Tao Li, Huiyong Zhang   +8 more
wiley   +1 more source

Double Alkynylation of Quinoline-5,8-diones and their In-silico and Antimicrobial Studies

Journal of Applied Sciences and Environmental Management, 2018
A double alkynylation of quinoline-5,8-dione to furnished bis-alkynylquinoline-5,8-dione in good yields and their in silico and antimicrobial studies is described.
MA Ezeokonkwo, JA Ezugwu, SN Okafor, EA Onoabedje, EU Godwin-Nwakwasi, FN Ibeanu   +5 more
doaj   +1 more source

Utilizing redox-sensitive GFP fusions to detect in vivo redox changes in a genetically engineered prokaryote

Redox Biology, 2019
Understanding the in vivo redox biology of cells is a complex albeit important biological problem. Studying redox processes within living cells without physical disruption or chemical modifications is essential in determining the native redox states of ...
Wilhad Hans Reuter, Thorsten Masuch, Na Ke, Marine Lenon, Meytal Radzinski, Vu Van Loi, Guoping Ren, Paul Riggs, Haike Antelmann, Dana Reichmann, Lars I. Leichert, Mehmet Berkmen   +11 more
doaj   +1 more source

INCREASED EXPRESSION OF GLUTAREDOXIN 1 (Grx1) PROTECTS HUMAN RETINAL PIGMENT EPITHELIAL CELLS FROM OXIDATIVE DAMAGE

, 2014
Oxidative stress is believed to contribute to the pathogenesis of many diseases, including age-related macular degeneration (AMD), in which retinal pigment epithelial (RPE) cells are considered as major targets.
Liu, Xiaobin, Jann, Jamieson, Wu, Hongli
core  

Positive Regulation of Interleukin-1β Bioactivity by Physiological ROS-Mediated Cysteine S-Glutathionylation

Cell Reports, 2017
Reactive oxygen species (ROS)-induced cysteine S-glutathionylation is an important posttranslational modification (PTM) that controls a wide range of intracellular protein activities.
Xue Zhang, Peng Liu, Christie Zhang, Direkrit Chiewchengchol, Fan Zhao, Hongbo Yu, Jingyu Li, Hiroto Kambara, Kate Y. Luo, Arvind Venkataraman, Ziling Zhou, Weidong Zhou, Haiyan Zhu, Li Zhao, Jiro Sakai, Yuanyuan Chen, Ye-Shih Ho, Besnik Bajrami, Bing Xu, Leslie E. Silberstein, Tao Cheng, Yuanfu Xu, Yuehai Ke, Hongbo R. Luo   +23 more
doaj   +1 more source

Macrophage-restricted overexpression of glutaredoxin 1 protects against atherosclerosis by preventing nutrient stress-induced macrophage dysfunction and reprogramming. [PDF]

Atherosclerosis, 2023
Ahn YJ, Wang L, Kim S, Eber MR, Salerno AG, Asmis R.   +5 more
europepmc   +1 more source

Regulatation of hepatic lipid metabolism by glutaredoxin‐1 and protein glutathione‐adducts

The FASEB Journal, 2015
Objective Oxidants can contribute to cellular signaling via glutathione‐(GSH) adducts, which are reversible post‐translational modifications of proteins that alter their function. Glutaredoxin‐1 (Glrx) is an enzyme that specifically removes these GSH‐adducts and modulates enzyme activity ...
Di Shao, Jingyan Han, Xiuyun Hou, Jessica Fry, Jessica Behring, Chunxiang Yao, Xiang Weng, David Pimentel, Michelle Long, Hemant Roy, Francesca Seta, Richard Cohen, Reiko Matsui, Markus Bachschmid   +13 more
openaire   +1 more source

HSP₇₀ Modulators for the Correction of Cognitive, Mnemonic, and Behavioral Disorders After Prenatal Hypoxia

Biomedicines
Background/Objectives: Prenatal hypoxia (PH) is a leading cause of nervous system disorders in early childhood and subsequently leads to a decline in the cognitive and mnemonic functions of the central nervous system (such as memory impairment, reduced ...
Olena Aliyeva, Igor F. Belenichev, Ivan Bilai, Iryna Duiun, Lyudmyla Makyeyeva, Valentyn Oksenych, Oleksandr Kamyshnyi   +6 more
doaj   +1 more source