Results 91 to 100 of about 107,521,968 (199)

Glutathione- and glutaredoxin-dependent reduction of methionine sulfoxide reductase A

, 2012
A natural fusion occurring between two tandemly repeated glutaredoxin (Grx) modules and a methionine sulfoxide reductase A (MsrA) has been detected in Gracilaria gracilis.
Couturier, Jérémy, Vignols, Florence, Jacquot, Jean-Pierre, Rouhier, Nicolas   +3 more
core   +1 more source

Redox regulation of ischemic limb neovascularization – What we have learned from animal studies

Redox Biology, 2017
Mouse hindlimb ischemia has been widely used as a model to study peripheral artery disease. Genetic modulation of the enzymatic source of oxidants or components of the antioxidant system reveal that physiological levels of oxidants are essential to ...
Reiko Matsui, Yosuke Watanabe, Colin E. Murdoch   +2 more
doaj   +1 more source

The E3 Ubiquitin Ligases SINA3 and SINA5 Control DEP2 Ubiquitination and Proteasomal Degradation to Regulate Grain Size and Weight in Rice

Plant Biotechnology Journal, Volume 24, Issue 10, Page 5483-5497, October 2026.
ABSTRACT Grain size is a critical agronomic trait, yet the molecular mechanisms governing its determination in crops remain incompletely understood. While recent studies revealed that OsRING80 facilitates DENSE AND ERECT PANICLE 2 (DEP2) degradation to mediate immunity without impacting growth and development, our work identifies a distinct regulatory ...
Hongming Wu, Xiejun Sun, Xin Wang, Chen Xie, Yingli Lv, Xiaoman You, Yu Zhang, Xiaohang Han, Yun Zhu, Yimin Lin, Yehui Xiong, Qibing Lin, Cailin Lei, Xiuping Guo, Shanshan Zhu, Zhijun Cheng, Yulong Ren, Ling Jiang, Jianmin Wan   +18 more
wiley   +1 more source

A novel CsRNF‐CsHSF24‐CsF3′5′H2 module regulates epigallocatechin gallate biosynthesis in Camellia sinensis

The Plant Journal, Volume 128, Issue 1, October 2026.
Significance Statement While the biosynthetic pathway of tea catechins is well established, how post‐translational modifications govern this process has remained elusive. This study uncovers a regulatory module in which the E3 ubiquitin ligase CsRNF targets the transcription factor CsHSF24 for degradation, thereby controlling expression of the key ...
Xinzhuan Yao, Hufang Chen, Haili An, Yilan Hu, Tong Li, Qi Zhao, Tengxian He, Chao Luo, Xiaofang Zeng, Litang Lu   +9 more
wiley   +1 more source

Novel Glutaredoxin Gene in Soybean Responds to Aluminum Toxicity in Soil [PDF]

, 2001
Oxidative stress generated by aerobic metabolism or from environmental sources is a major cause of damage to organisms. Aluminum is a major toxin in acidic soils and one proposed source of oxidative stress.
Thomas-Bostic, Kisha D.
core  

Purification from Placenta, Amino Acid Sequence, Structure Comparisons and cDNA Cloning of Human Glutaredoxin

, 1995
Glutaredoxin is generally a glutathione-dependent hydrogen donor for ribonucleotide reductase and also catalyses general glutathione (GSH)-disulfide-oxidoreduction reactions in the presence of NADPH and glutathione reductase.
Bárcena, J. A.,, Arne Holmgren, C. Alicia Padilla, Spyrou, Giannis,, Emilia Martínez‐Galisteo, PADILLA, CA, HOLMGREN, A, SPYROU, G, J. Antonio Bárcena, BARCENA, JA, Martínez-Galisteo, E.,, Holmgren, A.,, Giannis Spyrou, Padilla, C. A.,, MARTINEZGALISTEO, E   +14 more
core   +1 more source

Inherited microcytic anemias due to disorders of iron and heme metabolism: An updated clinical review

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Microcytic anemia is among the most common hematological abnormalities in clinical practice and is usually attributable to iron deficiency, thalassemia traits, or anemia of inflammation. A small but clinically important subset of patients, however, has inherited disorders of iron metabolism or heme synthesis presenting with persistent ...
Alexandros Makis, Ioanna Saougou, Eleftheria Hatzimichael   +2 more
wiley   +1 more source

Biochemical and biophysical characterization of a mycoredoxin protein glutaredoxin A1 from Corynebacterium pseudotuberculosis

, 2018
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Processo FAPESP: 2009/53989-4Processo FAPESP: 2015/13765 ...
Monika A. Coronado, Raghuvir K. Arni, Raphael J. Eberle, Eberle, Raphael J. [UNESP], Tasic, Ljubica, de Moraes, Fabio R., Arni, Raghuvir K., Fabio R. de Moraes, Kawai, Liege A. [UNESP], Arni, Raghuvir K. [UNESP], Eberle, Raphael J., Kawai, Liege A., Coronado, Monika A. [UNESP], Liege A. Kawai, Coronado, Monika A., Ljubica Tasic, de Moraes, Fabio R. [UNESP]   +16 more
core   +1 more source

Iron‐Sulfur Cluster Targeting: A Novel Perspective for Treating Alcohol‐Related Lipid Metabolic Diseases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Alcohol metabolism induces structural instability of iron‐sulfur clusters through ROS‐mediated oxidative damage and direct covalent modification of acetaldehyde. The iron‐sulfur cluster deficiency drives metabolic reprogramming by inactivating aconitase, accumulating succinate, and impairing tRNA thiolation, thereby promoting hepatic steatosis ...
Li Xu, Zhenyang Xu, Chenli Su, Yanqian Zhao, Linjing Qiang, Xiayong Jing, Yuxiang Sun   +6 more
wiley   +1 more source

Identification of glutaredoxin 1 and glutaredoxin 2 genes from Venerupis philippinarum and their responses to benzo[a]pyrene and bacterial challenge

, 2012
Glutaredoxin (abbreviated as Grx) is an important ubiquitous disulfide reductase, which can protect organisms against oxidative stresses. In the present study, a monothiol glutaredoxin gene (named as VpGrx1) and a dithiol glutaredoxin gene (named as ...
Wang, Chunlin, Yuan, Zeyi, Zhang, Zhendong, Mu, Changkao, Wang, Qing   +4 more
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