Results 71 to 80 of about 107,521,968 (199)

Bioinformatics pre-selection of thioredoxin/glutaredoxin target proteins for the construction of cellular redox regulatory network [PDF]

, 2012
Lee H-M. Bioinformatics pre-selection of thioredoxin/glutaredoxin target proteins for the construction of cellular redox regulatory network. Bielefeld: Bielefeld University; 2012.The gradually accumulated knowledge of molecular interaction is assembled ...
Lee, Hang-Mao
core  

Deciphering the functional roles of glutaredoxin 1 in chub mackerel (

Comparative Immunology Reports
Glutaredoxins (Grxs) are crucial components of the cellular antioxidant defense system, maintaining redox homeostasis and protecting against oxidative stress.
W.P.S.N. Wijeweera, Jeganathan Tharshan Jeyakanesh, D.M.K.P. Sirisena, R.I. Sandeepani, E.M.T. Tharanga, Cheong Uk Park, Hanchang Sohn, Qiang Wan, Jehee Lee   +8 more
doaj   +1 more source

Epigallocatechin-3-gallate enhances key enzymatic activities of hepatic thioredoxin and glutathione systems in selenium-optimal mice but activates hepatic Nrf2 responses in selenium-deficient mice

Redox Biology, 2016
Selenium participates in the antioxidant defense mainly through a class of selenoproteins, including thioredoxin reductase. Epigallocatechin-3-gallate (EGCG) is the most abundant and biologically active catechin in green tea.
Ruixia Dong, Dongxu Wang, Xiaoxiao Wang, Ke Zhang, Pingping Chen, Chung S. Yang, Jinsong Zhang   +6 more
doaj   +1 more source

A comprehensive study on ferredoxin isoforms in the cyanobacterium Synechocystis sp. PCC 6803

The FEBS Journal, EarlyView.
Ferredoxins are small FeS cluster‐containing proteins that play a central role in distributing electrons within the cell. The cyanobacterium Synechocystis sp. PCC 6803 contains several ferredoxin isoforms and their biophysical properties (UV/Vis and EPR spectra, Em potential), expression patterns, and interactions with the electron donors photosystem I
Marko Boehm, Drazenka Svedruzic, Carolyn E. Lubner, Jens Appel, David W. Mulder, Effie C. Kisgeropoulos, Vanessa Hueren, Katharina Spengler, Vivek S. Bharadwaj, Zhanjun Guo, Anastasia E. Ledinina, Darja Deobald, Lorenz Adrian, Paul W. King, Kirstin Gutekunst   +14 more
wiley   +1 more source

Monothiol Glutaredoxin-1 Is an Essential Iron-Sulfur Protein in the Mitochondrion of African Trypanosomes [PDF]

Journal of Biological Chemistry, 2008
African trypanosomes encode three monothiol glutaredoxins (1-C-Grx). 1-C-Grx1 occurs exclusively in the mitochondrion, and 1-C-Grx2 and -3 are predicted to be mitochondrial and cytosolic proteins, respectively. All three 1-C-Grx are expressed in both the mammalian bloodstream and the insect procyclic form of Trypanosoma brucei, with the highest levels ...
Marcelo A, Comini, Jochen, Rettig, Natalie, Dirdjaja, Eva-Maria, Hanschmann, Carsten, Berndt, R Luise, Krauth-Siegel   +5 more
openaire   +2 more sources

S‑glutathionylation of MaWRKY44 orchestrates a MaZFP139‐MaWRKY44‐MaGSTU07 cascade to enhance banana cold tolerance

Journal of Integrative Plant Biology, EarlyView.
In banana, at low temperatures (7°C), the transcription factor MaZFP139 activates MaWRKY44 expression. MaWRKY44 binds to the W‐box sites in the promoter of the glutathione S‐transferase gene MaGSTU07 to enhance reactive oxygen species scavenging. S‐glutathionylation protects MaWRKY44 from oxidation‐induced degradation, reinforcing antioxidant defenses ...
Shuqin Lin, Wen Song, Shaoting Liao, Haike Tan, Jianji Qi, Danling Cai, Wei Wei, Wei Shan, Jianfei Kuang, Jianye Chen, Wangjin Lu   +10 more
wiley   +1 more source

Drug Interactions with Glutaredoxin Orthologues [PDF]

, 2015
Glutaredoxin, an enzymatic protein, is an important component of cell viability and function. It catalyzes reactions involved in DNA synthesis and innate immunity [1,4].
Leeper, Thomas C, Davis, Caroline, Morris, Daniel, Napper, Kahlilah R, Khattri, Ram   +4 more
core  

In vitro and in silico assessment of new beta amino ketones with antiplasmodial activity

Revista da Sociedade Brasileira de Medicina Tropical, 2022
Background: Based on the current need for new drugs against malaria, our study evaluated eight beta amino ketones in silico and in vitro for potential antimalarial activity.
Gabriela Camila Krombauer, Karla de Sena Guedes, Felipe Fingir Banfi, Renata Rachide Nunes, Amanda Luisa da Fonseca, Ezequias Pessoa de Siqueira, Jéssica Côrrea Bezerra Bellei, Kézia Katiani Gorza Scopel, Fernando de Pilla Varotti, Bruno Antônio Marinho Sanchez   +9 more
doaj   +1 more source

Embryonal degreening and seed longevity require plastid LEA proteins

New Phytologist, EarlyView.
Working model of how plastidial LEA proteins aid the remodelling of photosynthetic structures during degreening of Arabidopsis seed embryos. LEA42 and LEA48 support thylakoid proteostasis and membrane remodelling in embryonal cells during late seed maturation by maintaining a local physicochemical environment compatible with protein turnover and ...
Dennis Brandt, Ana Carolina Vilchez, Jürgen Eirich, Paulina Heinkow, Lea Hembach, Ke Zheng, Pedro Barreto, Jan‐Ole Niemeier, Lando Lebok, Ivo Feussner, Felix Buchert, Alexey Amunts, Kristina Kühn, David Macherel, Till Ischebeck, Michael Melzer, Iris Finkemeier, Markus Schwarzländer   +17 more
wiley   +1 more source

Modulation of thiol-dependent redox system by metal ionsviathioredoxin and glutaredoxin systems

, 2018
Metal and metalloid ions regulate thioredoxin and glutaredoxin system-mediated biological functions by targeting mammalian thioredoxin reductase and mitochondrial glutaredoxin 2&5.
Jing Li, Arne Holmgren, Yanfang Ouyang, Yi Peng, Jun Lu, Holmgren, A,, Ouyang, Y, Li, J, Lu, J, Peng, Y   +9 more
core   +1 more source