Results 61 to 70 of about 107,521,968 (199)

Time‐Resolved Effects of Cold Atmospheric Plasma on E. coli GW‐AmxH19 Transcriptome and Proteome in an Emulated Wastewater Environment

PROTEOMICS, EarlyView.
ABSTRACT Cold atmospheric plasma (CAP) is effective against a variety of microorganisms. Here, we described effects on an Escherichia coli strain isolated from hospital wastewater caused by treatment with physical plasma. E. coli GW‐AmxH19 was incubated in artificial wastewater and treated for 15 min with CAP.
Jörg Bernhardt, Dominik Schneider, Julia Rielicke, Susanne Sievers, Veronika Hahn, Mechthild Bömeke, Anja Poehlein, Dirk Albrecht, Juergen F. Kolb, Katharina Riedel, Rolf Daniel, Daniela Zühlke   +11 more
wiley   +1 more source

The Thioltransferase (Glutaredoxin) 1 Gene of Fission Yeast Is Regulated by Atf1 and Pap1

Molecules and Cells, 2003
We previously isolated a gene encoding thioltransferase (TTase1) from the fission yeast Schizosaccharomyces pombe. Using a TTase-lacZ fusion plasmid, carrying a 666 bp region upstream of the translation initiation point, we found that expression of TTase1 was enhanced by metal ions, diamide and NO-generating S-nitroso-N-acetylpenicillamine (SNAP).
Chang-Jin, Lim, Young-Wook, Cho, Sung-Min, Hong, Hye-Won, Lim, Eun-Hee, Park   +4 more
openaire   +2 more sources

Glutaredoxin-1 Mediates NADPH-Dependent Stimulation of Calcium-Dependent Insulin Secretion [PDF]

Molecular Endocrinology, 2009
Nicotinamide adenine dinucleotide phosphate (NADPH) enhances Ca(2+)-induced exocytosis in pancreatic beta-cells, an effect suggested to involve the cytosolic redox protein glutaredoxin-1 (GRX-1). We here detail the role of GRX-1 in NADPH-stimulated beta-cell exocytosis and glucose-stimulated insulin secretion.
Thomas M, Reinbothe, Rosita, Ivarsson, Dai-Qing, Li, Omid, Niazi, Xingjun, Jing, Enming, Zhang, Lena, Stenson, Ulrika, Bryborn, Erik, Renström   +8 more
openaire   +2 more sources

Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip

eLife, 2020
Antioxidant systems, such as the thioredoxin-1 (Trx1) pathway, ensure cellular redox homeostasis. However, how such systems regulate development and function of myeloid cells is barely understood.
Jonathan Muri, Helen Thut, Qian Feng, Manfred Kopf   +3 more
doaj   +1 more source

Alternative [2Fe‐2S] donor assemblies in the cytosol: GLRX3 and GLRX3‐BOLA2 converge on NUBP1 maturation

The FEBS Journal, EarlyView.
GLRX3 homodimer and GLRX3‐BOLA2 heterotrimer act as alternative [2Fe‐2S] donor assemblies for NUBP1 maturation. Both systems support formation of [4Fe‐4S] cluster‐bound NUBP1, but display distinct kinetic dependence on the physiological electron donor anamorsin, which accelerates GLRX3‐mediated transfer but does not enhance GLRX3‐BOLA2‐mediated ...
Martina Masini, Rosanna Cuccaro, Lucia Banci   +2 more
wiley   +1 more source

Glutaredoxin regulates vascular development by reversible glutathionylation of sirtuin 1

, 2013
Embryonic development depends on complex and precisely orchestrated signaling pathways including specific reduction/oxidation cascades. Oxidoreductases of the thioredoxin family are key players conveying redox signals through reversible posttranslational
Dahl Ejby Jensen, Lasse,, Montano, Sergio J,, Dreij, Kristian,, Poschmann, Gereon,, Uhlen, Per,, Brautigam, Lars,, Prozorovski, Timour,, Bannenberg, Sarah,, Lepka, Klaudia,, Holmgren, Arne,, Nystrom, Staffan,, Stuehler, Kai,, Aktas, Orhan,, Cao, Yihai,, Berndt, Carsten,, Bannenberg, S, Montano, SJ, Dreij, K,, Prozorovski, T, Jensen, LDE, Aktas, O, Nystrom, S,, Poschmann, G, Lepka, K, Brautigam, L   +24 more
core   +1 more source

Irreversible Inactivation of Glutaredoxins 1 and 2 by Peroxynitrite

Bulletin of the Korean Chemical Society, 2007
who showedthat rat liver cytosolic fractions lose glutaredoxin activitywhen treated with peroxynitrite. Considering the potentialrole of S-glutathionylation in signaling, inactivation ofglutaredoxins by reactive nitrogen species deserves detailedstudy.We report here that peroxynitrite among the nitric oxidecongeners is a very effective inactivator of ...
openaire   +2 more sources

The impact of glutaredoxin 1 and glutaredoxin 2 double knockout on lens epithelial cell function

Experimental Eye Research, 2023
Glutaredoxins (Grx1 and Grx2) are thiol-repair antioxidant enzymes that play vital roles in cellular redox homeostasis and various cellular processes. This study aims to evaluate the functions of the glutaredoxin (Grx) system, including glutaredoxin 1 (Grx1) and glutaredoxin 2 (Grx2), using Grx1/Grx2 double knockout (DKO) mice as a model.
Jinmin, Zhang, Yu, Yu, Terry, Dang, Kevin, Lal, Hongli, Wu   +4 more
openaire   +2 more sources

Glutaredoxin 2 promotes SP-1-dependent CSPG4 transcription and migration of wound healing NG2 glia and glioma cells: Enzymatic Taoism

Redox Biology, 2022
Redox regulation of specific cysteines via oxidoreductases of the thioredoxin family is increasingly being recognized as an important signaling pathway.
Christina Wilms, Klaudia Lepka, Felix Häberlein, Steven Edwards, Jörg Felsberg, Linda Pudelko, Tobias T. Lindenberg, Gereon Poschmann, Nan Qin, Katrin Volbracht, Tim Prozorovski, Sven G. Meuth, Ulf D. Kahlert, Marc Remke, Orhan Aktas, Guido Reifenberger, Lars Bräutigam, Benjamin Odermatt, Carsten Berndt   +18 more
doaj   +1 more source

Reactive oxygen species, antioxidants and the regulation of plant development

The FEBS Journal, EarlyView.
The regulation of axillary bud outgrowth by the interplay between phytohormone and redox signals. Axillary bud outgrowth is regulated by cellular energy status and the balance between phytohormones, notably abscisic acid (ABA) and gibberellic acid (GA).
Juwita R. Dewi, Christine H. Foyer, Michael J. Considine   +2 more
wiley   +1 more source