Results 111 to 120 of about 9,840 (178)

Glutaredoxin-1 regulates the Keap1-Nrf2 pathway [PDF]

, 2017
PURPOSE: The Nrf2/Keap1/ARE pathway is a major regulator of cytoprotective responses to oxidants. Gluatredoxin-1 (Glrx-1), a small thiol transferase removes glutathione (GSH) adducts from proteins and participates in redox signaling. Glrx-/- mice exhibit
Kim, Maya Hwewon
core  

Quinoa bioester application shifts human skin proteome toward molecular profiles associated with younger age

Communications Biology
Skin aging involves complex molecular changes that current strategies struggle to reverse. Here, we developed a machine learning approach using Support Vector Regression to predict biological skin age from proteomic profiles, enabling objective ...
Amanda C. Camillo-Andrade, Lucas A. Sales, Carolina M. Catarino, Bruna Bosquetti, Camila F. S. Oliveira, Patricia H. Szuchman, Andrezza D. P. M. Canavez, Ana Raquel I. Firmino, Rodrigo C. Romanhole, Gustavo Dieamant, Desiree C. Shuck, Rosario Duran, Juliana S. G. Fischer, Marlon D. M. Santos, Paulo C. Carvalho   +14 more
doaj   +1 more source

Monothiol and dithiol glutaredoxin-1 from Clostridium oremlandii: identification of domain-swapped structures by NMR, X-ray crystallography and HDX mass spectrometry. [PDF]

IUCrJ, 2020
Lee K, Yeo KJ, Choi SH, Lee EH, Kim BK, Kim S, Cheong HK, Lee WK, Kim HY, Hwang E, Woo JR, Lee SJ, Hwang KY.   +12 more
europepmc   +1 more source

Regulation of DJ-1 by glutaredoxin 1 \u3ci\u3ein vivo – implications for Parkinson’s disease\u3c/i\u3e

, 2016
Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide, caused by the degeneration of the dopaminergic neurons in the substantia nigra.
Wang, Wenzhang, Yao, Chen, Wilson-Delfosse, Amy L., Mieyal, John J., Curran, Pierce L., Gorelenkova Miller, Olga, Johnson, William M., Choe, Kyonghwan, Wilson, Mark A., Zhu, Xiongwei, Ray, Ajit, Golczak, Marcin, Milkovic, Nicole M., Chen, Shu G., Lin, Jiusheng, Ravindranath, Vijayalakshmi   +15 more
core   +1 more source

Characterization of the arsenate reductase of Escherichia coli plasmid R773.

, 1999
Bacterial resistance to toxic anions in Escherichia coli is carried on the R773 plasmid. The plasmid contains the ars operon, which encodes a group of proteins responsible for the extrusion of arsenicals and antimonials out of the cell.
Perri, Domenic.
core  

Glutaredoxin-1 attenuates transactive response DNA-binding protein 43-induced neurotoxicity by suppressing oxidative stress and transactive response DNA-binding protein 43 aggregation. [PDF]

Neuroreport
Lee JM, Bok E, Kim SR, Kim J.
europepmc   +1 more source

POTENTIAL DRUG TARGETS FOR ALOIN AND MICRODONTIN: AN IN-SILICO ANALYSIS

, 2016
Objective: The aim of this study was to study the interactions of Aloin and microdontin with antimalarial drug targets.Methods: The ADMET properties of Aloin and microdontin were analyzed using LigandScout and Osiris Molecular Property Predictor tools ...
Ravi, Lokesh, Ragunathan, Adhithya
core   +1 more source

Glutaredoxin and glutathione regulate the activity of ATP7A AND ATP7B

, 2012
In this study it was shown that the antioxidant, glutathione, and the glutaredoxin-1 protein, have important new roles in regulating ATP7A and ATP7B - two key proteins which regulate intracellular copper levels in humans - by modulating how they bind ...
W Singleton (12145599)
core