Results 101 to 110 of about 9,840 (178)

Enhancement of protein production in Aspergillus niger by engineering the antioxidant defense metabolism

Biotechnology for Biofuels and Bioproducts
Background Research on protein production holds significant importance in the advancement of food technology, agriculture, pharmaceuticals, and bioenergy.
Xin Chen, Baoxiang Pan, Leyi Yu, Bin Wang, Li Pan   +4 more
doaj   +1 more source

The role of glutaredoxin-1 on B16F0 melanoma growth and angiogenesis in diet-induced diabetic mice [PDF]

, 2018
OBJECTIVES: Recent studies have elucidated that diabetes mellitus (DM) patients exhibit an accelerated tumor progression, but the mechanism of its regulation is not yet fully understood. The following study seeks to examine the role of angiogenic factors
Chong, Brian Sung Ho
core  

Determining the effect of glutaredoxin-1 overexpression on the growth of B16F0 tumors in mus musculus [PDF]

, 2017
BACKGROUND: While advances in medicine have led to increased survival rates, cancer is responsible for millions of deaths each year. Melanoma itself accounts for tens of thousands of these deaths, and is capable of progressing rapidly.
Johnson, Ryan David Patrick
core  

Targeted disruption of the glutaredoxin 1 gene does not sensitize adult mice to tissue injury induced by ischemia/reperfusion and hyperoxia

, 2007
To understand the physiological function of glutaredoxin, a thiotransferase catalyzing the reduction of mixed disulfides of protein and glutathione, we generated a line of knockout mice deficient in the cytosolic glutaredoxin 1 (Grx1).
Pai, Harish, Gao, Jinping, Ho, Ye-Shih, Ho, Dorothy S., Mieyal, John J., Chua, Balvin H.L., Ho, Ye Shih, Xiong, Ye   +7 more
core   +2 more sources

Glutaredoxin-1 and Others Antioxidants Enzymes in Two Subtypes (B-cell and T-cell) of Acute Lymphoblastic Leukemia Patients

The 5-year event-free viability for acute lymphoblastic leukemia (ALL) have enhanced in many study groups due to modern paediatric clinical trials, however T-cell ALL results are still lagging by 5–10% in most studies.
Al-Helaly, Luay Abed, Younes, Saqima Harbi   +1 more
core   +2 more sources

Characterization of a major polysaccharide from Sagittaria trifolia L. and its protective effects on cataract

Journal of Agriculture and Food Research
The objective of this study was to isolate and characterize polysaccharides from Sagittaria trifolia L. tubers and to investigate their potential protective effects against cataract.
Jian-bin Sun, Man-yu Zhou, Bi-sui Yang, Xiao-li Mei, Liang-ke Zhang, Wei-zao Luo, Yan Liao   +6 more
doaj   +1 more source

Redox homeostasis and inflammation in fibroblasts of patients with Friedreich Ataxia: a possible cross talk

Frontiers in Molecular Neuroscience
Redox homeostasis is impaired in Friedreich’s Ataxia (FRDA), a neurodegenerative disease caused by the decreased expression of the mitochondrial protein frataxin.
Andrea Quatrana, Sara Petrillo, Caterina Torda, Eleonora De Santis, Enrico Bertini, Fiorella Piemonte   +5 more
doaj   +1 more source

Glutaredoxin-1 [PDF]

, 2020
openaire   +1 more source

Insights into the Multifaceted Roles of Thioredoxin-1 System: Exploring Knockout Murine Models

Biology
Redox balance is increasingly identified as a major player in cellular signaling. A fundamentally simple reaction of oxidation and reduction of cysteine residues in cellular proteins is the central concept in this complex regulatory mode of protein ...
Tetiana Shcholok, Eftekhar Eftekharpour
doaj   +1 more source

Oxidative Stress Defense Module in Lung Cancers: Molecular Pathways and Therapeutic Approaches

Antioxidants
The regulation of oxidative stress is an effective strategy for treating cancers. Therapeutic strategies for modulating an undesirable redox balance against cancers have included the enhancement of oxidative components, reducing the action of antioxidant
Eunsun Lee, Jeong Hee Hong
doaj   +1 more source