Results 11 to 20 of about 12,387 (173)
Utility of Synechocystis sp. PCC glutaredoxin A as a platform to study high-resolution mutagenesis of proteins. [PDF]
Frontiers in Plant Science, 2013 Glutaredoxin from the cyanobacterium Synechocystis sp. PCC 6803 is a small protein, containing only 88 amino acids, that participates in a large number of redox reactions, serving both as an electron donor for enzyme-catalyzed reductions and as a ...
David B Knaff, Roger Bryan Sutton
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Journal of Integrative Bioinformatics, 2010 A significant part of cellular proteins undergo reversible thiol-dependent redox transitions which often control or switch protein functions. Thioredoxins and glutaredoxins constitute two key players in this redox regulatory protein network.
Lee Hang-mao +2 more
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Deletion of glutaredoxin promotes oxidative tolerance and intracellular infection in Listeria monocytogenes [PDF]
Virulence, 2019 Thiol-disulfide glutaredoxin systems of bacterial cytoplasm favor reducing conditions for the correct disulfide bonding of functional proteins, and therefore were employed by bacteria to defend against oxidative stress.
Jing Sun +14 more
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S-Denitrosylation: A Crosstalk between Glutathione and Redoxin Systems
Antioxidants, 2022 S-nitrosylation of proteins occurs as a consequence of the derivatization of cysteine thiols with nitric oxide (NO) and is often associated with diseases and protein malfunction.
Surupa Chakraborty +8 more
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FEBS Open Bio, 2023 Glutaredoxins (Grxs) are small proteins that share a well‐conserved thioredoxin (Trx)‐fold and participate in many biological processes. This study examined the cold adaptation mechanism of a Fe‐S cluster binding class II Grx4 (SpGrx4) from the ...
Trang Hoang +3 more
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Frontiers in Endocrinology, 2018 Histomorphological and functional alterations in pancreatic islet composition directly correlate with hyperglycemia severity. Progressive deterioration of metabolic control in subjects suffering from type 2 diabetes is predominantly caused by impaired ...
Sebastian Friedrich Petry +4 more
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mBio, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for coronavirus disease 2019 (COVID-19), encodes two proteases required for replication.
David A. Davis +9 more
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Intracellular glutathione pools are heterogeneously concentrated [PDF]
, 2013 Glutathione is present in millimolar concentrations in the cell, but its relative distribution among cellular compartments remains elusive. We have chosen the endoplasmic reticulum (ER) as an example organelle to study compartment-specific glutathione ...
Christine Tachibana +12 more
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An NMR-Guided Screening Method for Selective Fragment Docking and Synthesis of a Warhead Inhibitor
Molecules, 2016 Selective hits for the glutaredoxin ortholog of Brucella melitensis are determined using STD NMR and verified by trNOE and 15N-HSQC titration. The most promising hit, RK207, was docked into the target molecule using a scoring function to compare ...
Ram B. Khattri +7 more
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Thiol-based redox regulation in sexual plant reproduction: new insights and perspectives
Frontiers in Plant Science, 2013 The success of sexual reproduction in plants involves (i) the proper formation of the plant gametophytes (pollen and embryo sac) containing the gametes, (ii) the accomplishment of specific interactions between pollen grains and the stigma, which ...
Jose A Traverso +3 more
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