Results 31 to 40 of about 11,635 (216)
Glutaredoxins and thioredoxins in plants
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2008 During the 70s and 80s two plant thioredoxin systems were identified. The chloroplastic system is composed of a ferredoxin-dependent thioredoxin, with two thioredoxin types (m and f) regulating the activity of enzymes implicated in photosynthetic carbon assimilation. In the cytosol of heterotrophic tissues, an NADP dependent thioredoxin reductase and a
Meyer, Yves +5 more
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Clinical and Translational Medicine, 2023 Background Lymphangioleiomyomatosis (LAM) is a female‐predominant interstitial lung disease, characterized by progressive cyst formation and respiratory failure.
Ya Feng +10 more
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The Yeast Glutaredoxins Are Active as Glutathione Peroxidases [PDF]
Journal of Biological Chemistry, 2002 The yeast Saccharomyces cerevisiae contains two glutaredoxins, encoded by GRX1 and GRX2, which are active as glutathione-dependent oxidoreductases. Our studies show that changes in the levels of glutaredoxins affect the resistance of yeast cells to oxidative stress induced by hydroperoxides.
Collinson, Emma J. +5 more
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Potential Role of Sulfur-Containing Antioxidant Systems in Highly Oxidative Environments
Molecules, 2014 All forms of life maintain a reducing environment (homeostasis) within their cells. Perturbations in the normal redox state can lead to an oxidative environment which has deleterious effects, especially in health.
Emmanuel Mukwevho +2 more
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IUCrJ, 2020 Protein dimerization or oligomerization resulting from swapping part of the protein between neighboring polypeptide chains is known to play a key role in the regulation of protein function and in the formation of protein aggregates.
Kitaik Lee +12 more
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Antioxidants, 2022 Hypoxia is a major environmental stressor that can damage the oxidation metabolism of crustaceans. Glutaredoxin (Grx) is a key member of the thioredoxin superfamily and plays an important role in the host’s defense against oxidative stress.
Yu-Kun Jie +6 more
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Antioxidants, 2022 Glutathione (GSH), a major antioxidant in mammalian cells, regulates several vital cellular processes, such as nutrient metabolism, protein synthesis, and immune responses. In addition to its role in antioxidant defense, GSH controls biological processes
Elizabeth Corteselli +2 more
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The Thioredoxin-Regulated α-Amylase 3 of Arabidopsis thaliana Is a Target of S-Glutathionylation
Frontiers in Plant Science, 2019 Reactive oxygen species (ROS) are produced in cells as normal cellular metabolic by-products. ROS concentration is normally low, but it increases under stress conditions. To stand ROS exposure, organisms evolved series of responsive mechanisms.
Libero Gurrieri +9 more
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Structural and Functional Diversity of Glutaredoxins in Yeast [PDF]
Current Protein & Peptide Science, 2010 Glutaredoxins are defined as thiol disulfide oxidoreductases that reduce disulfide bonds employing reduced glutathione as electron donor. They constitute a complex family of proteins with a diversity of enzymatic and functional properties. Thus, dithiol glutaredoxins are able to reduce disulfide bonds and deglutathionylate mixed disulfides between ...
Herrero Perpiñán, Enrique +2 more
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Comparison of structures among Saccharomyces cerevisiae Grxs proteins
Genes and Environment, 2018 Glutaredoxins (Grxs) comprise a group of glutathione (GSH)-dependent oxidoreductase enzymes that respond to oxidative stress and sustain redox homeostasis.
Mohnad Abdalla +2 more
doaj +1 more source