Results 41 to 50 of about 11,635 (216)

Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip

eLife, 2020
Antioxidant systems, such as the thioredoxin-1 (Trx1) pathway, ensure cellular redox homeostasis. However, how such systems regulate development and function of myeloid cells is barely understood.
Jonathan Muri, Helen Thut, Qian Feng, Manfred Kopf   +3 more
doaj   +1 more source

Thioredoxin and Glutaredoxin Systems [PDF]

, 2019
This Special Issue features recent data concerning thioredoxins and glutaredoxins from various biological systems, including bacteria, mammals, and plants. Four of the sixteen articles are review papers that deal with the regulation of development of the effect of hydrogen peroxide and the interactions between oxidants and reductants, the description ...
Zaffagnini, Mirko, Jacquot, Jean-Pierre
openaire   +3 more sources

Expression Analysis of a Novel Oxidoreductase Glutaredoxin 2 in Black Tiger Shrimp, Penaeus monodon

Antioxidants, 2022
Glutaredoxin (Grx) is a glutathione-dependent oxidoreductase that is an important component of the redox system in organisms. However, there is a serious lack of sequence information and functional validation related to Grx in crustaceans. In this study,
Rui Fan, Yundong Li, Qibin Yang, Song Jiang, Jianhua Huang, Lishi Yang, Xu Chen, Falin Zhou, Shigui Jiang   +8 more
doaj   +1 more source

Molecular Characterization and Expression Analysis of a Novel Glutaredoxin 3 Gene in Pacific White Shrimp (Litopenaeus vannamei)

Frontiers in Marine Science, 2021
Glutaredoxins (Grxs), small heat-stable oxidoreductases, are key members of the thioredoxin (Trx) superfamily. Recently, an emerging subclass of Grxs with a cysteine residue in the active site was found in shrimps.
Peihua Zheng, Peihua Zheng, Xiuxia Zhang, Xiuxia Zhang, Dongmei Wang, Dongmei Wang, Juntao Li, Juntao Li, Zelong Zhang, Zelong Zhang, Yaopeng Lu, Yaopeng Lu, Jianan Xian, Jianan Xian, Anli Wang, Lei Wang   +15 more
doaj   +1 more source

A Rice CPYC-Type Glutaredoxin OsGRX20 in Protection against Bacterial Blight, Methyl Viologen and Salt Stresses

Frontiers in Plant Science, 2018
Glutaredoxins (GRXs) belong to the antioxidants involved in the cellular stress responses. In spite of the identification 48 GRX genes in rice genomes, the biological functions of most of them remain unknown.
Xi Ning, Yao Sun, Changchun Wang, Weilin Zhang, Meihao Sun, Haitao Hu, Jianzhong Liu, Ling Yang   +7 more
doaj   +1 more source

Glutaredoxin AtGRXS8 represses transcriptional and developmental responses to nitrate in Arabidopsis thaliana roots

Plant Direct, 2020
Glutaredoxins (GRXs) are small oxidoreductase enzymes that can reduce disulfide bonds in target proteins. The class III GRX gene family is unique to land plants, and Arabidopsis thaliana has 21 class III GRXs, which remain largely uncharacterized.
Ahmad Ehrary, Miguel Rosas, Sophia Carpinelli, Oscar Davalos, Craig Cowling, Francisco Fernandez, Matthew Escobar   +6 more
doaj   +1 more source

Photo-labelling of glutaredoxin from Escherichia coli

, 1982
N,N′-bis (4-azidobenzoyl) glutathione disulphide (1) was a strong inhibitor of glutaredoxin in the dark. The presence of 1 caused the velocity versus glutathione concentration curves of the glutaredoxin activity as assayed by E.
D'Silva, Claudius, Douglas, Kenneth T.; id_orcid, Holmgren, Arne, Höög, Jan Olav   +3 more
core   +1 more source

Missing links in understanding redox signaling via thiol/disulfide modulation: How is glutathione oxidized in plants?

Frontiers in Plant Science, 2013
Glutathione is a small redox-active molecule existing in two main stable forms: the thiol (GSH) and the disulphide (GSSG). In plants growing in optimal conditions, the GSH:GSSG ratio is high in most cell compartments. Challenging environmental conditions
Marie-Sylviane eRahantaniaina, Marie-Sylviane eRahantaniaina, Andree eTuzet, Amna eMhamdi, Graham eNoctor   +4 more
doaj   +1 more source

Thioredoxin system modulates metabolic and stomatal responses to elevated CO2 in Arabidopsis

New Phytologist, EarlyView.
Integrative model of extraplastidial NADPH‐dependent thioredoxin reductase/thioredoxin system‐mediated regulation of stomatal function, redox homeostasis, and metabolic responses under ambient and elevated CO2 in Arabidopsis thaliana. Summary The NADPH‐dependent thioredoxin reductase/thioredoxin (NTR/TRX) system plays a central role in maintaining ...
Paula da Fonseca‐Pereira, Domingos F. Mélo Neto, Rita de Cássia Monteiro‐Batista, Daniel Gomes Coelho, Jaciara Lana‐Costa, Leonardo Perez de Souza, Ina Krahnert, Danilo M. Daloso, Jorge Gago, Alisdair R. Fernie, Wagner L. Araújo, Adriano Nunes‐Nesi   +11 more
wiley   +1 more source

Long‐Term Salt Exposure Reprograms the Nicotiana tabacum BY‐2 Suspension Proteome and Metabolome Toward Stabilization of the Core Metabolic Pathways, Protein Turnover Machinery Modifications, and Protective Metabolome Adjustments

Plant, Cell &Environment, EarlyView.
ABSTRACT In this study, we analyzed a unique Nicotiana tabacum BY‐2 line that was gradually adapted to and subsequently maintained in 190 mM NaCl for over 15 years. Years of continuous high salinity shaped a stable “new homeostasis” in BY‐2 suspension cells. Salt‐adapted cells were smaller and formed tighter clusters. Metabolomics revealed constitutive
Anita Rzadkiewicz, Łukasz Marczak, Aleksander Strugała, Maria Tomys, Ewelina Ratajczak, Tomasz Skrzypczak, Przemysław Wojtaszek, Anna Kasprowicz‐Maluśki, Agnieszka Szuba   +8 more
wiley   +1 more source