Results 61 to 70 of about 11,635 (216)

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

Glutaredoxin regulates vascular development by reversible glutathionylation of sirtuin 1

, 2013
Embryonic development depends on complex and precisely orchestrated signaling pathways including specific reduction/oxidation cascades. Oxidoreductases of the thioredoxin family are key players conveying redox signals through reversible posttranslational
Dahl Ejby Jensen, Lasse,, Montano, Sergio J,, Dreij, Kristian,, Poschmann, Gereon,, Uhlen, Per,, Brautigam, Lars,, Prozorovski, Timour,, Bannenberg, Sarah,, Lepka, Klaudia,, Holmgren, Arne,, Nystrom, Staffan,, Stuehler, Kai,, Aktas, Orhan,, Cao, Yihai,, Berndt, Carsten,   +14 more
core   +1 more source

Effect of RNAi Targeting SeGrx1 on the Cytotoxicity and Insecticide Susceptibility of Camptothecin in Spodoptera exigua

Agriculture, 2022
Glutaredoxins (Grxs) are a class of small, heat-stable, acidic proteins which have been implied in various biological activities in cells, including the defense against oxidative stress induced by various biotic and abiotic factors.
Fulai Yang, Lan Zhang, Yanning Zhang, Liangang Mao, Lizhen Zhu, Xingang Liu, Hongyun Jiang   +6 more
doaj   +1 more source

Under the Cover of Darkness: A Transcriptomic Exploration of Clubroot During the Night

Plant Direct, Volume 10, Issue 6, June 2026.
ABSTRACT Plasmodiophora brassicae (Phytomyxea, Rhizaria) is the etiological agent of clubroot disease, one of the most important diseases of Brassicaceae crops. Alteration of metabolism and hormone homeostasis leads to the formation of tumor‐like galls in the roots of affected plants.
Andrea Garvetto, Susann Auer, Freia Benade, Michaela Hittorf, Jutta Ludwig‐Müller, Sigrid Neuhauser   +5 more
wiley   +1 more source

Towards a refined classification of class I dithiol glutaredoxins from poplar: biochemical basis for the definition of two subclasses

Frontiers in Plant Science, 2013
Glutaredoxins (Grxs) are small oxidoreductases particularly specialized in the reduction of protein-glutathione adducts. Compared to other eukaryotic organisms, higher plants present an increased diversity of Grxs which are organized into four classes ...
Jérémy eCouturier, Jérémy eCouturier, Jean-Pierre eJacquot, Jean-Pierre eJacquot, Nicolas eRouhier, Nicolas eRouhier   +5 more
doaj   +1 more source

Sketching microprotein portraits

Protein Science, Volume 35, Issue 6, June 2026.
Abstract The illustrations of intricate molecular machineries inside cells created by David Goodsell continue to inspire the scientific community. Here, we aim to extend his artworks to include microproteins, a newly recognized class of small proteins with less than 100 amino acids, encoded by small open reading frames.
Gabriel Diaz, Philippe Valenti, Marc Gueroult, Simon Marques‐Prieto, Kenza Benachenhou, Jennifer Zanet, Matthieu Chavent   +6 more
wiley   +1 more source

Glutaredoxin is a direct target of oncogenic jun [PDF]

Oncogene, 1998
We have analysed differential gene expression in v-jun-transformed chicken embryo fibroblasts (CEF) compared to normal CEF by using the directional tag PCR subtraction method. From a first generation of putative Jun targets four clones were selected for study; they are upregulated in jun-transformed cells. Three of these clones showed homology to known
M E, Goller, J S, Iacovoni, P K, Vogt, U, Kruse   +3 more
openaire   +2 more sources

Genetic dissection and transcriptomic analysis of a novel high‐tillering phenotype in rice derived from weedy rice (Hapcheonaengmi3) and Tongil‐type Rice (Milyang23)

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Rice (Oryza sativa L.) tillering is a critical determinant of grain yield, yet the genetic mechanisms underlying non‐productive tillers remain poorly understood. Here, we report a novel high‐tillering (HT) phenotype derived from a cross between the elite cultivar Milyang23 and weedy rice Hapcheonaengmi3. The HT phenotype was absent in parental
Kyu‐Chan Shim, Donghyun Jeon, Yun‐A Jeon, Cheryl Adeva, Hyun‐Sook Lee, Ju‐Won Kang, Sa‐Eun Park, Sang‐Nag Ahn, Inkyu Park   +8 more
wiley   +1 more source

Immunolocalization of glutaredoxin in the human corpus luteum [PDF]

Molecular Human Reproduction, 1999
Glutaredoxin (Grx) is a small protein with oxidoreductase activity which is involved in the cellular defence against oxidative stress. Corpus luteum (CL) regression has been related to the generation of reactive oxygen species (ROS). We have studied the presence of glutaredoxin in the human ovary during the ovulatory cycle using polyclonal antibodies ...
L, García-Pardo, M D, Granados, F, Gaytán, C A, Padilla, E, Martínez-Galisteo, C, Morales, J E, Sánchez-Criado, J A, Bárcena   +7 more
openaire   +2 more sources

Mechanism of 1-Cys type methionine sulfoxide reductase Aregeneration by glutaredoxin

, 2021
1-Cys MsrA; Disulfide bond; Glutaredoxin; Glutathionylation ...
이공주
core   +1 more source