Results 11 to 20 of about 625,340 (244)

Glutathione and mitochondria [PDF]

open access: yesFrontiers in Pharmacology, 2014
Glutathione (GSH) is the main non-protein thiol in cells whose functions are dependent on the redox-active thiol of its cysteine moiety that serves as a cofactor for a number of antioxidant and detoxifying enzymes. While synthesized exclusively in the cytosol from its constituent amino acids, GSH is distributed in different compartments, including ...
Carmen García-Ruiz   +4 more
openaire   +5 more sources

Glutathione [PDF]

open access: yesThe Arabidopsis Book, 2011
Glutathione is a simple sulfur compound composed of three amino acids and the major non-protein thiol in many organisms, including plants. The functions of glutathione are manifold but notably include redox-homeostatic buffering. Glutathione status is modulated by oxidants as well as by nutritional and other factors, and can influence protein structure
Graham, Noctor   +4 more
openaire   +2 more sources

Expression of Heterologous OsDHAR Gene Improves Glutathione (GSH)-Dependent Antioxidant System and Maintenance of Cellular Redox Status in Synechococcus elongatus PCC 7942. [PDF]

open access: yes, 2020
An excess of reactive oxygen species (ROS) can cause severe oxidative damage to cellular components in photosynthetic cells. Antioxidant systems, such as the glutathione (GSH) pools, regulate redox status in cells to guard against such damage ...
Beld, Joris   +9 more
core   +2 more sources

Glutathione in the Brain [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Glutathione (GSH) is the most abundant non-protein thiol, and plays crucial roles in the antioxidant defense system and the maintenance of redox homeostasis in neurons. GSH depletion in the brain is a common finding in patients with neurodegenerative diseases, such as Alzheimer’s disease and Parkinson’s disease, and can cause neurodegeneration prior to
openaire   +3 more sources

GLUTATHIONE DETERMINATION AND A STUDY OF THE ACTIVITY OF GLUTATHIONE-PEROXIDASE, GLUTATHIONE-TRANSFERASE, AND GLUTATHIONE-REDUCTASE IN RENAL TRANSPLANTS [PDF]

open access: yesRenal Failure, 2002
The aim of this work is to study the temporary variation of oxidative stress in renal transplants, both in plasma and in erythrocytes (CR). In order to do so, we determined total glutathione (GST) levels, both oxidized (GSSG) and reduced (GSH), and the activity of enzymes, glutathione peroxidase (G-px), glutathione reductase (G-red) and glutathione ...
Vega, L. de   +5 more
openaire   +4 more sources

A reverse chemical ecology approach to explore wood natural durability [PDF]

open access: yes, 2020
The natural durability of wood species, defined as their inherent resistance to wood‐destroying agents, is a complex phenomenon depending on many biotic and abiotic factors.
Amusant, Nadine   +8 more
core   +1 more source

Insulin-like Growth Factor 1 and Transforming Growth Factor-β Stimulate Cystine/Glutamate Exchange Activity in Dental Pulp Cells [PDF]

open access: yes, 2011
Introduction The growth factors insulin-like growth factor (IGF-1) and transforming growth factor-β (TGF-β) are protective to dental pulp cells in culture against the toxicity of the composite materials Durafill VS and Flow Line (Henry Schein Inc, New ...
Alyssa Furey   +39 more
core   +2 more sources

Adaptive response to oxidative stress in the filamentous fungus Aspergillus niger B1-D [PDF]

open access: yes, 2008
In the present study, we used a recombinant filamentous fungus strain, Aspergillus niger B1-D, as a model system, and investigated the antioxidant defences in this organism.
Harvey, L.M., Li, Qiang, Mcneil, Brian
core   +1 more source

Nanosensor for Glutathione

open access: yesStudents encountering science – StES 2022, 2022
Mesoporous silica nanoparticles (MSN) are promising materials for bioanalyte detection and targeted drug delivery applications due to their characteristic properties, large specific surface area and porosity, and the possibility of surface functionalization.
Pavlović, Aleksandra   +2 more
openaire   +3 more sources

Understanding cisplatin resistance using cellular models [PDF]

open access: yes, 2007
Many mechanisms of cisplatin resistance have been proposed from studies of cellular models of resistance including changes in cellular drug accumulation, detoxification of the drug, inhibition of apoptosis and repair of the DNA adducts.
Davey, Mary W., Stordal, Britta
core   +2 more sources

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