Results 11 to 20 of about 971,313 (343)

Prodrug Approach for Increasing Cellular Glutathione Levels

Molecules, 2010
Reduced glutathione (GSH) is the most abundant non-protein thiol in mammalian cells and the preferred substrate for several enzymes in xenobiotic metabolism and antioxidant defense.
Ivana Cacciatore, Catia Cornacchia, Francesco Pinnen, Adriano Mollica, Antonio Di Stefano   +4 more
doaj   +1 more source

Adaptive response to oxidative stress in the filamentous fungus Aspergillus niger B1-D [PDF]

, 2008
In the present study, we used a recombinant filamentous fungus strain, Aspergillus niger B1-D, as a model system, and investigated the antioxidant defences in this organism.
Harvey, L.M., Li, Qiang, Mcneil, Brian
core   +1 more source

Plasma glutathione and oxidized glutathione level, glutathione/oxidized glutathione ratio, and albumin concentration in complicated and uncomplicated falciparum malaria

Asian Pacific Journal of Tropical Biomedicine, 2016
Objective: To compare the level of glutathione (GSH) and oxidized glutathione (GSSG), the ratio of GSH/GSSG and the concentration of albumin in plasma of patients with complicated and un-complicated falciparum malaria.
Loeki Enggar Fitri, Agustin Iskandar, Teguh Wahju Sardjono, Ummu Ditya Erliana, Widya Rahmawati, Didi Candradikusuma, Utama Budi Saputra, Eko Suhartono, Bambang Setiawan, Erma Sulistyaningsih   +9 more
doaj   +1 more source

Evaluation of the antioxidant activity of Zingiber officinale alcoholic extract and vitamin e on liver damage induced by paracetamol drug in males of New Zealand rabbits [PDF]

Iraqi Journal of Veterinary Sciences, 2022
The aim of study is to reduce hepatic damage from paracetamol will be funded using alcohol extract for ginger and vitamin E as antioxidants in male New Zealand rabbits.
Dakheel H. Hadree, Abdulkhaliq A. Farhan, Raouf M. Fadhil   +2 more
doaj   +1 more source

Insulin-like Growth Factor 1 and Transforming Growth Factor-β Stimulate Cystine/Glutamate Exchange Activity in Dental Pulp Cells [PDF]

, 2011
Introduction The growth factors insulin-like growth factor (IGF-1) and transforming growth factor-β (TGF-β) are protective to dental pulp cells in culture against the toxicity of the composite materials Durafill VS and Flow Line (Henry Schein Inc, New ...
Alyssa Furey, Asrari, Barthel, Bègue-Kirn, Cabrera, Camargo, Doug Lobner, Duailibi, D’Souza, Fogal, Franco, Furey, Goldberg, Gronthos, Hansen, Hu, Kalyva, Katherine Pauly, Kaur, Keelan, Kim, Kim, Kymberly Fritz, Lobner, Lovschall, Marcato, Nie, Onishi, Pacheco, Paranjpe, Piani, Piattelli, Ricketts, Rutherford, Stanley, Stockton, Tziafas, Tziafas, Ward, Wood   +39 more
core   +2 more sources

Glutathione Deficiency in Sinorhizobium meliloti Does Not Impair Bacteroid Differentiation But Induces Early Senescence in the Interaction With Medicago truncatula

Frontiers in Plant Science, 2020
Under nitrogen-limiting conditions, legumes are able to interact symbiotically with bacteria of the Rhizobiaceae family. This interaction gives rise to a new organ, named a root nodule. Root nodules are characterized by an increased glutathione (GSH) and
Li Yang, Sarra El Msehli, Sofiane Benyamina, Annie Lambert, Julie Hopkins, Julie Cazareth, Olivier Pierre, Didier Hérouart, Samira Achi-Smiti, Eric Boncompagni, Pierre Frendo   +10 more
doaj   +1 more source

Glutathione in Brain Disorders and Aging

Molecules, 2022
Glutathione is a remarkably functional molecule with diverse features, which include being an antioxidant, a regulator of DNA synthesis and repair, a protector of thiol groups in proteins, a stabilizer of cell membranes, and a detoxifier of xenobiotics ...
I. Y. Iskusnykh, A. A. Zakharova, D. Pathak   +2 more
semanticscholar   +1 more source

Understanding cisplatin resistance using cellular models [PDF]

, 2007
Many mechanisms of cisplatin resistance have been proposed from studies of cellular models of resistance including changes in cellular drug accumulation, detoxification of the drug, inhibition of apoptosis and repair of the DNA adducts.
Davey, Mary W., Stordal, Britta
core   +2 more sources

Glutathione in the Brain

International Journal of Molecular Sciences, 2021
Glutathione (GSH) is the most abundant non-protein thiol, and plays crucial roles in the antioxidant defense system and the maintenance of redox homeostasis in neurons.
K. Aoyama
semanticscholar   +1 more source

Centrality of G6PD in COVID-19: The Biochemical Rationale and Clinical Implications

Frontiers in Medicine, 2020
Introduction: COVID-19 is a novel and devastating disease. Its manifestations vary from asymptomatic to lethal. Moreover, mortality rates differ based on underlying health conditions and ethnicity.
Yuliya Buinitskaya, Roman Gurinovich, Clifford G. Wlodaver, Siarhei Kastsiuchenka   +3 more
doaj   +1 more source