Acetoacetate enhancement of glucose mediated DNA glycation
M. Bagherzadeh-Yazdi +8 more
openalex +1 more source
This study characterizes a newly‐described intervertebral fat pad (IVFP) anterior to rat IVDs, with evidence for its existence in mice and human IVDs as well. In rats, the IVFP gradually degenerated following IVD injury with changes in adipocyte size and fibrous tissue infiltration, suggesting it could play a functional role in IVD health and ...
Niklas H. Koehne +7 more
wiley +1 more source
Systematic characterization of lysine glucuronidation in a bispecific antibody. [PDF]
Reyda MR +7 more
europepmc +1 more source
Abstract Background The coexistence of frailty and type 2 diabetes mellitus in the older population heightens the risk of adverse events. However, research on functional and wellness factors associated with frailty in this population is limited. Purpose To investigate the associations of physical performance, functional dependency, physical activity ...
Juan Corral‐Pérez +5 more
wiley +1 more source
Methylglyoxal-induced glycation stress promotes aortic stiffening: putative mechanistic roles of oxidative stress and cellular senescence. [PDF]
Singh P +16 more
europepmc +1 more source
Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-α–Dependent Pathway [PDF]
Vicki Thallas‐Bonke +9 more
openalex +1 more source
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth +5 more
wiley +1 more source
Effect of Different High-Temperature Heating Methods on the Glycation Reaction and Advanced Glycation Reaction Products of <i>β</i>-Lactoglobulin. [PDF]
Zhang X +8 more
europepmc +1 more source
Autoimmunity and Periodontitis
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
Bacterial Adaptation to Stress Induced by Glyoxal/Methylglyoxal and Advanced Glycation End Products. [PDF]
Kuczyńska-Wiśnik D +2 more
europepmc +1 more source

