Results 31 to 40 of about 44,199 (236)
International Archives of Otorhinolaryngology, 2016 Introduction High mobility group box 1 is a versatile protein involved in gene transcription, extracellular signaling, and response to inflammation. Extracellularly, high mobility group box 1 binds to several receptors, notably the receptor for advanced ...
Austin Nguyen +4 more
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Do advanced glycation end products contribute to food allergy?
Frontiers in Allergy, 2023 Sugars can bind non-enzymatically to proteins, nucleic acids or lipids and form compounds called Advanced Glycation End Products (AGEs). Although AGEs can form in vivo, factors in the Western diet such as high amounts of added sugars, processing methods ...
P. K. Smith +4 more
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BMC Musculoskeletal Disorders, 2010 Background Levels of pentosidine (representative of advanced glycation end-products) in sera of patients with rheumatoid arthritis are increased when compared with sera of other diagnoses or healthy controls.
Vilím Vladimír +2 more
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Tumor Biology, 2017 Receptor for advanced glycation end products and glyoxalase I metabolizing advanced glycation end product precursors may play important role in the pathogenesis and progression of cancer.
Petra Tesarova +3 more
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Evaluation of the AGE/sRAGE Axis in Patients with Multiple Myeloma
Antioxidants, 2019 Glycative stress influences tumor progression. The aim of the present study was to evaluate the advanced glycation end products/soluble receptor of advanced glycation end products (AGE/sRAGE) axis in patients with multiple myeloma (MM).
Alessandro Allegra +10 more
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Impact of intracellular toxic advanced glycation end-products (TAGE) on murine myoblast cell death
Diabetology & Metabolic Syndrome, 2020 Background Sarcopenia is a progressive condition that is characterized by decreases in skeletal muscle mass and function. Although sarcopenia is associated with lifestyle-related diseases (LSRD), the mechanisms underlying cell death in myoblasts, which ...
Takanobu Takata +2 more
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Advanced Glycation End-products and Atherosclerosis
Annals of Medicine, 1996 The late rearrangements of the covalent nonenzymatic modification of proteins by glucose, called advanced glycation end-products (AGEs), have been shown to accumulate in diabetic and ageing tissues. AGEs elicit a wide range of cell-mediated responses leading to vascular dysfunction, matrix expansion and athero- and glomerulosclerosis.
openaire +2 more sources
Advanced glycation end products and diabetic retinopathy [PDF]
Journal of Ocular Biology, Diseases, and Informatics, 2012 Studies have established hyperglycemia as the most important factor in the progress of vascular complications. Formation of advanced glycation end products (AGEs) correlates with glycemic control. The AGE hypothesis proposes that hyperglycemia contributes to the pathogenesis of diabetic complications including retinopathy.
Arvind Mishra +4 more
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Sacrificial Biofabrication for Vascularization: Concept, Materials, Technologies, and Applications
Advanced Materials, EarlyView.Vasculature is indispensable for tissue viability in regenerative medicine. The sacrificial biofabrication enables precise fabrication of vascular channels by using temporary templates that are subsequently removed. This review defines the concept and delves into sacrificial materials, surrounding materials, fabrication technologies, and biomedical ...
Jiezhong Shi +7 more
wiley +1 more source
Decoding Dental Stem Cell Aging: Mechanisms, Therapeutic Strategies, and Beyond
Advanced Science, EarlyView.Dental stem cell (DSC) aging involves genomic instability, mitochondrial dysfunction, telomere attrition, and epigenetic alterations, leading to impaired proliferation, reduced differentiation potential, and pro‐inflammatory secretory activity. These processes drive cellular senescence and compromise regenerative and immunomodulatory functions, thereby
Xinyuan Zhao +7 more
wiley +1 more source