Results 141 to 150 of about 20,599 (278)
Biological Reviews, Volume 101, Issue 5, Page 2103-2118, October 2026.ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu +12 more
wiley +1 more source
Environmental Toxicology, Volume 41, Issue 10, Page 1105-1118, October 2026.ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye +5 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 17, 15 September 2026.Transcriptomic and metabolomic profiling of Ornithodoros lahorensis during African swine fever virus (ASFV) infection reveals that ASFV rewires host purine/pyrimidine metabolism, lipid metabolism, and energy metabolism. A core gene‐metabolite regulatory axis consisting of 12 key genes and 8 signature metabolites is identified to support viral genome ...
Jin Luo +9 more
wiley +1 more source
FEBS Letters, Volume 600, Issue 17, Page 2564-2578, September 2026.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Advanced Science, Volume 13, Issue 51, 14 September 2026.This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo +6 more
wiley +1 more source
ENT1 inhibition links oligodendrocyte lipid metabolism to connectivity in tauopathy
Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.Abstract INTRODUCTION Metabolic dysfunction, altered adenosine signaling, and white matter abnormalities are implicated in tauopathies, but their relationship to network disconnection remains unclear. Myelinating oligodendrocytes may represent a metabolically vulnerable hub linking these processes to circuit dysfunction.
Ching‐Pang Chang +7 more
wiley +1 more source
Perinatal lead (Pb) exposure and alterations to amyloid beta and metabolic profiles in the brain
Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.Abstract INTRODUCTION Developmental neurotoxicant exposures (e.g., lead [Pb]) are suspected contributors to dementia. Dementia is characterized by amyloid beta (Aβ) plaques and dysregulated metabolism. To better understand the relationship between environment and dementia risk, we assessed the impact of perinatal Pb exposure on dementia‐related ...
Rachel K. Morgan +10 more
wiley +1 more source
Arthritis &Rheumatology, Volume 78, Issue 9, Page 1850-1862, September 2026.Objective Osteoarthritis, the leading cause of disability worldwide, disproportionately affects women, yet sex remains an overlooked determinant. This disparity stems from sex‐specific differences in injury susceptibility—a major risk factor for disease.
Hope D. Welhaven +6 more
wiley +1 more source
Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.Sixteen species belonging to the Malpighiaceae family were analyzed by UHPLC‐MS/MS in both positive and negative ionization modes, and the resulting metabolomic data were subjected to chemometric analyses to investigate the patterns of chemodiversity across different Brazilian biomes.
Jaqueline Munise Guimarães da Silva +3 more
wiley +1 more source