Results 141 to 150 of about 21,259 (271)

Securing Long‐Chain Omega‐3 Fatty Acid Supply for Sustainable Aquaculture Development and Human Nutrition

open access: yesReviews in Aquaculture, Volume 19, Issue 1, January 2027.
Omega‐3 LC‐PUFA lie at the intersection of aquaculture performance and human nutrition. Deployment of w3 LC‐PUFA rich microalgal oils derived from low trophic levels offers credible long‐term sustainable solutions, taking full account of the potential environmental footprints and benefits in terms of human nutrition and health.
Sadasivam Kaushik, Douglas R. Tocher
wiley   +1 more source

Biofilm Development and Stage‐Specific Multi‐Omics Analysis of Metschnikowia bicuspidata Associated With Milky Disease in the Eriocheir sinensis

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 6, December 2026.
ABSTRACT Metschnikowia bicuspidata, the causative agent of milky disease in the Chinese mitten crab (Eriocheir sinensis), is an important aquatic pathogenic yeast in freshwater aquaculture. However, the developmental characteristics and molecular regulation of its biofilm formation remain poorly understood.
Yitong Deng   +5 more
wiley   +1 more source

Remodelling of Skeletal Muscle During Iron Deficiency Anaemia and Recovery After Intravenous Iron Therapy

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 6, December 2026.
ABSTRACT Background The global prevalence of iron deficiency anaemia (IDA) is about 25% and even higher in women of reproductive age and children. IDA can impair skeletal muscle by disrupting oxygen utilization, energy production and contractile function. Haematological effects of intravenous (IV) iron therapy in IDA are well studied, but its impact on
Elke Pertler   +18 more
wiley   +1 more source

Highly Efficient Microscale Purification of Glycerophospholipids by Microfluidic Cell Lysis and Lipid Extraction for Lipidomics Profiling

open access: yes, 2016
This article presents a novel method for small-scale lipidomics of bacterial cells by integrating extraction of glycerophospholipids on a microchip with a nanoelectrospray ionization quadrupole time-of-flight tandem mass spectrometer (nanoESI-Q-TOF MS/MS)
Mitchell E. Johnson (2173048)   +2 more
core   +1 more source

Characterization of the Lysophosphatidic Acid Receptor 5 Antagonist RLPA‐76 as a Novel Analgesic in Male Rats and Mice

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Clinically used analgesics such as gabapentinoids and opioids have limited efficacy and adverse effects like abuse liability, and there is a dire need for novel analgesics with improved safety profiles. Since lysophosphatidic acid can induce neuropathic pain in rodents, LPA receptor antagonists have been investigated as potential analgesics ...
Kristen L. Woodhouse   +6 more
wiley   +1 more source

Imaging of intracellular fatty acids by scanning X-ray fluorescence microscopy

open access: yes, 2016
International audienceFatty acids are taken up by cells and incorporated into complex lipids such as neutral lipids and glycerophospholipids. Glycerophospholipids are major constituents of cellular membranes. More than 1000 mol.
Tokuoka, S. M.   +14 more
core   +1 more source

Regulation of IL‐13 Signaling by Retinoic Acid in Airway Epithelial Cells

open access: yesThe FASEB Journal, Volume 40, Issue 21, 15 November 2026.
Our proteomics and subsequent biochemical analyses reveal the effects of retinoic acid receptor (RAR) agonists, ATRA (pan‐RAR agonist), or CD1530 (RARγ agonist) in counteracting molecular changes induced by IL‐13 relevant to airway inflammation and remodeling, such as proteins involved in epithelial‐to‐mesenchymal transition (EMT) and extracellular ...
Vanshika Patel   +5 more
wiley   +1 more source

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 11, Page 3079-3105, November 2026.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu   +23 more
wiley   +1 more source

Plasma Lipidomic Features of Adolescent Major Depressive Disorder and Lipid Changes After Fluoxetine Treatment

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
Dysregulated plasma lipid homeostasis with aberrant triglycerides, lysophospholipids, and membrane sphingolipids represents a core pathological feature of adolescent major depressive disorder. Eight‐week fluoxetine treatment remodels lipid profiles including bile acid metabolites and modulates key signaling pathways, supporting novel lipid‐based ...
Chenxi Liu   +16 more
wiley   +1 more source

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