Results 1 to 10 of about 76,168 (194)
Glycogen synthase activity in Candida albicans is partly controlled by the functional ortholog of Saccharomyces cerevisiae Gac1p [PDF]
mSphereTo adapt to various host microenvironments, the human fungal pathogen Candida albicans possesses the capacity to accumulate and store glycogen as an internal carbohydrate source.
Jian Miao +3 more
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Mechanism of glycogen synthase inactivation and interaction with glycogenin [PDF]
Nature Communications, 2022 Glycogen is a major energy reserve in eukaryotes and is synthesised in part by glycogenin (GN) and glycogen synthase (GS). Here, authors describe the structural basis of GS regulation, specifically the mechanism of inactivation by phosphorylation.
Laura Marr +13 more
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Intermittent Fasting Modulates the Glycogen Level in Zebrafish (Danio rerio) and their Next Generation [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: Zebrafish (Danio rerio) has become the best model organism to study the evolutionary biological process and human developmental studies.
ShanmugaSundaram Tamilarasan +2 more
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Gsk-3$ \beta $ aggravates depression symptoms in a chronic stress mouse model [PDF]
Journal of Integrative Neuroscience, 2018 Depression caused by genetic and environmental factors is acomplicated disease. Here, it is demonstrated that glycogen synthase kinase-3$\beta$ is highly expressed and phosphorylated in the brain of a chronic stress mouse. Inhibition of glycogen synthase
Hong Peng, Hong-bin Wang, Ling Wang, Bing Zhou, Xiao-yong Li, Jian Tan
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Biology, 2021 Glycogen synthase kinase-3 beta is a ubiquitously and constitutively expressed molecule with pleiotropic function. It acts as a protooncogene in the development of several solid tumors including pancreatic cancer through its involvement in various ...
Robin Park +3 more
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Regulatory Functions of Nilaparvata lugens GSK-3 in Energy and Chitin Metabolism
Frontiers in Physiology, 2020 Glucose metabolism is a biologically important metabolic process. Glycogen synthase kinase (GSK-3) is a key enzyme located in the middle of the sugar metabolism pathway that can regulate the energy metabolism process in the body through insulin signaling.
Yan-Juan Ding +7 more
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Variations in Glycogen Synthesis in Human Pluripotent Stem Cells with Altered Pluripotent States. [PDF]
PLoS ONE, 2015 Human pluripotent stem cells (hPSCs) represent very promising resources for cell-based regenerative medicine. It is essential to determine the biological implications of some fundamental physiological processes (such as glycogen metabolism) in these stem
Richard J Chen +6 more
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Alternative splicing of the porcine glycogen synthase kinase 3β (GSK-3β) gene with differential expression patterns and regulatory functions. [PDF]
PLoS ONE, 2012 Glycogen synthase kinase 3 (GSK3α and GSK3β) are serine/threonine kinases involved in numerous cellular processes and diverse diseases including mood disorders, Alzheimer's disease, diabetes, and cancer.
Linjie Wang +7 more
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Neural Regeneration Research, 2020 Isoflurane and sevoflurane are both inhalation anesthetics, but in clinical application, sevoflurane has been considered to be less suitable for long-term anesthesia because of its catabolic compounds and potential nephrotoxicity.
Ying Du +5 more
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Neural Regeneration Research, 2017 Myocardial ischemia/reperfusion injury can lead to severe brain injury. Glycogen synthase kinase 3 beta is known to be involved in myo-cardial ischemia/reperfusion injury and diabetes mellitus. However, the precise role of glycogen synthase kinase 3 beta
Bo Zhao +7 more
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