Results 11 to 20 of about 76,168 (194)
The inactivation of glycogen phosphorylase is not a prerequisite for the activation of liver glycogen synthase [PDF]
FEBS Letters, 1979 Carlos J. Ciudad +2 more
openalex +5 more sources
The Hysteretic Properties of Glycogen Synthase I [PDF]
European Journal of Biochemistry, 1977 Glycogen‐free synthase I from human polymorphonuclear leukocytes is activated by its own substrate, glycogen, in a slow, time‐dependent proces (hysteretic activation). This lag in response to addition of glycogen depends on the concentration of glycogen, pH and temperature.
Henrik Sølling, Viggo Esmann
openalex +5 more sources
Isozymes of glycogen synthase [PDF]
FEBS Letters, 1984 Antisera to rat skeletal muscle glycogen synthase failed to recognize liver glycogen synthase by electroblot analysis. The antisera recognized the enzyme in skeletal muscle, heart, fat, kidney, and brain. The results support the hypothesis that there are at least two isozymes of glycogen synthase, and that most tissues contain a form similar or ...
Harvey R. Kaslow, David D. Lesikar
openaire +3 more sources
Incorporation of phosphate into glycogen by glycogen synthase [PDF]
Archives of Biochemistry and Biophysics, 2016 The storage polymer glycogen normally contains small amounts of covalently attached phosphate as phosphomonoesters at C2, C3 and C6 atoms of glucose residues. In the absence of the laforin phosphatase, as in the rare childhood epilepsy Lafora disease, the phosphorylation level is elevated and is associated with abnormal glycogen structure that ...
Christopher J. Contreras +7 more
openaire +4 more sources
Liver Glycogen Synthase in Rats with a Glycogen‐Storage Disorder [PDF]
European Journal of Biochemistry, 1980 1. A strain of rats with a genetically‐determined liver glycogen‐storage disorder (gsd/gsd) caused by a deficiency of liver phosphorylase kinase has a very high concentration of glycogen in the liver with a total glycogen synthase activity higher than in liver of fed normal animals, but only a small amount of the enzyme in the active form.
Colin Watts, Rex S. Malthus
openaire +3 more sources
Glycogen Synthase Kinase‐3 [PDF]
International Journal of Alzheimer’s Disease, 2011 Glycogen synthase kinase-3 (GSK3) is a ubiquitous and promiscuous kinase that has been studied extensively for over four decades. Initial reports beginning in the 1970s described its role in cellular metabolic pathways fundamental to glucose metabolism, but in more recent years the number of reports describing aberrant GSK3 activity in pathological ...
Crouch, P +4 more
openaire +5 more sources
Allosteric Regulation of Glycogen Synthase Controls Glycogen Synthesis in Muscle [PDF]
Cell Metabolism, 2010 Glycogen synthase (GS), a key enzyme in glycogen synthesis, is activated by the allosteric stimulator glucose-6-phosphate (G6P) and by dephosphorylation through inactivation of GS kinase-3 with insulin. The relative importance of these two regulatory mechanisms in controlling GS is not established, mainly due to the complex interplay between multiple ...
Kei Sakamoto +9 more
openaire +5 more sources
Crystal Structure of an Archaeal Glycogen Synthase [PDF]
Journal of Biological Chemistry, 2006 Glycogen and starch synthases are retaining glycosyltransferases that catalyze the transfer of glucosyl residues to the non-reducing end of a growing alpha-1,4-glucan chain, a central process of the carbon/energy metabolism present in almost all living organisms.
Horcajada, Cristina +3 more
openaire +4 more sources
Nuclear glycogen synthase — fact or artifact? [PDF]
FEBS Letters, 1982 According to Oron [FEBS Lett. (1980) 118, 255–258], nuclear glycogen synthase represents an artifact of preparation in rat liver nuclei. We investigated the nuclei isolated from in vitro growing HD33 ascites cells with exclusively cytoplasmic, and from in vivo growing HD33 Ehrlich—Lettré ascites tumor cells with mainly intranuclear, glycogen deposition.
Christof Granzow +2 more
openaire +3 more sources
Fishes, 2023 Glycogen, a stored form of glucose, is an important form of energy for aquatic shellfish, contributing to the flavor and quality of the oyster. The glycogen synthase (GYS) and glycogen synthase kinase 3β (GSK3β) are two major enzymes in the glycogenesis.
Yan Wang +8 more
doaj +1 more source