Results 11 to 20 of about 448,615 (401)
The axis-inducing activity, stability and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3 [PDF]
Genes & Development, 1996 The serine/threonine kinase Xgsk-3 and the intracellular protein beta-catenin are necessary for the establishment of the dorsal-ventral axis in Xenopus.
C. Yost +5 more
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In vivo regulation of muscle glycogen synthase and the control of glycogen synthesis. [PDF]
Proceedings of the National Academy of Sciences, 1995 The activity of glycogen synthase (GSase; EC 2.4.1.11) is regulated by covalent phosphorylation. Because of this regulation, GSase has generally been considered to control the rate of glycogen synthesis. This hypothesis is examined in light of recent in vivo NMR experiments on rat and human muscle and is found to be quantitatively inconsistent with the
Robert G. Shulman +2 more
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Intermittent Fasting Modulates the Glycogen Level in Zebrafish (Danio rerio) and their Next Generation [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: Zebrafish (Danio rerio) has become the best model organism to study the evolutionary biological process and human developmental studies.
ShanmugaSundaram Tamilarasan +2 more
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Gsk-3$ \beta $ aggravates depression symptoms in a chronic stress mouse model [PDF]
Journal of Integrative Neuroscience, 2018 Depression caused by genetic and environmental factors is acomplicated disease. Here, it is demonstrated that glycogen synthase kinase-3$\beta$ is highly expressed and phosphorylated in the brain of a chronic stress mouse. Inhibition of glycogen synthase
Hong Peng, Hong-bin Wang, Ling Wang, Bing Zhou, Xiao-yong Li, Jian Tan
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Biology, 2021 Glycogen synthase kinase-3 beta is a ubiquitously and constitutively expressed molecule with pleiotropic function. It acts as a protooncogene in the development of several solid tumors including pancreatic cancer through its involvement in various ...
Robin Park +3 more
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Isozymes of glycogen synthase [PDF]
FEBS Letters, 1984 Antisera to rat skeletal muscle glycogen synthase failed to recognize liver glycogen synthase by electroblot analysis. The antisera recognized the enzyme in skeletal muscle, heart, fat, kidney, and brain. The results support the hypothesis that there are at least two isozymes of glycogen synthase, and that most tissues contain a form similar or ...
Harvey R. Kaslow, David D. Lesikar
openaire +3 more sources
ATP Synthase: A Moonlighting Enzyme with Unprecedented Functions [PDF]
Chem. Commun., 2022, 58, 2650-2653, 2021 ATP synthase's intrinsic molecular electrostatic potential (MESP) adds constructively to, and hence reinforces, the chemiosmotic voltage. This ATP synthase voltage represents a new free energy term that appears to have been overlooked. This term is at least roughly equal in order of magnitude and opposite in sign to the energy needed to be dissipated ...
arxiv +1 more source
Liver Glycogen Synthase in Rats with a Glycogen‐Storage Disorder [PDF]
European Journal of Biochemistry, 1980 1. A strain of rats with a genetically‐determined liver glycogen‐storage disorder (gsd/gsd) caused by a deficiency of liver phosphorylase kinase has a very high concentration of glycogen in the liver with a total glycogen synthase activity higher than in liver of fed normal animals, but only a small amount of the enzyme in the active form.
Colin Watts, Rex S. Malthus
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Glycogen Synthase Kinase‐3 [PDF]
International Journal of Alzheimer’s Disease, 2011 Glycogen synthase kinase-3 (GSK3) is a ubiquitous and promiscuous kinase that has been studied extensively for over four decades. Initial reports beginning in the 1970s described its role in cellular metabolic pathways fundamental to glucose metabolism, but in more recent years the number of reports describing aberrant GSK3 activity in pathological ...
Crouch, P +4 more
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Regulatory Functions of Nilaparvata lugens GSK-3 in Energy and Chitin Metabolism
Frontiers in Physiology, 2020 Glucose metabolism is a biologically important metabolic process. Glycogen synthase kinase (GSK-3) is a key enzyme located in the middle of the sugar metabolism pathway that can regulate the energy metabolism process in the body through insulin signaling.
Yan-Juan Ding +7 more
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