Results 101 to 110 of about 16,721 (247)

Chondrocytes Contribute to Alphaviral Disease Pathogenesis as a Source of Virus Replication and Soluble Factor Production

open access: yesViruses, 2018
Arthritogenic alphavirus infections often result in debilitating musculoskeletal disorders that affect the joints, muscle, and bone. In order to evaluate the infection profile of primary human skeletal muscle and chondrocyte cells to Ross River virus ...
Elisa X. Y. Lim   +7 more
doaj   +1 more source

A theoretical estimate for nucleotide sugar demand towards Chinese Hamster Ovary cellular glycosylation [PDF]

open access: yes, 2016
Glycosylation greatly influences the safety and efficacy of many of the highest-selling recombinant therapeutic proteins (rTPs). In order to define optimal cell culture feeding strategies that control rTP glycosylation, it is necessary to know how ...
Jimenez del Val, I   +2 more
core   +1 more source

Mass Spectrometry and Glycomics [PDF]

open access: yesOMICS: A Journal of Integrative Biology, 2010
Abstract Glycosylation defines the adhesive properties of animal cell surfaces and the surrounding extracellular environments. Because cells respond to stimuli by altering glycan expression, glycan structures vary according to spatial location in tissue and temporal factors.
openaire   +2 more sources

Targeting Human Parainfluenza Virus Type-1 Haemagglutinin-Neuraminidase with Mechanism-Based Inhibitors

open access: yesViruses, 2019
Human parainfluenza virus (hPIV) infections are a major cause of respiratory tract illnesses in children, with currently no available vaccine or drug treatment.
Tanguy Eveno   +4 more
doaj   +1 more source

An improved comprehensive strategy for deep and quantitative N-glycomics based on optimization of sample preparation, isotope-based data quality control and quantification, new N-glycan libraries and new algorithms [PDF]

open access: gold, 2020
Yudong Guan   +16 more
openalex   +1 more source

The impact of elevation of total bilirubin level and etiology of the liver disease on serum N-glycosylation patterns in mice and men [PDF]

open access: yes, 2010
The GlycoFibroTest and GlycoCirrhoTest are noninvasive alternatives for liver biopsy that can be used as a follow-up tool for fibrosis patients and to diagnose cirrhotic patients, respectively.
BLOMME, BRAM   +5 more
core   +1 more source

Disruption of IL-17-mediated immunosurveillance in the respiratory mucosa results in invasive Streptococcus pyogenes infection

open access: yesFrontiers in Immunology
IntroductionStreptococcus pyogenes is a Gram-positive pathogen that causes a significant global burden of skin pyoderma and pharyngitis. In some cases, infection can lead to severe invasive streptococcal diseases.
Jamie-Lee Mills   +10 more
doaj   +1 more source

EUROCarbDB: An open-access platform for glycoinformatics [PDF]

open access: yes, 2017
The EUROCarbDB project is a design study for a technical framework, which provides sophisticated, freely accessible, open-source informatics tools and databases to support glycobiology and glycomic research. EUROCarbDB is a relational database containing
Blank, Dennis   +33 more
core  

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