Results 11 to 20 of about 16,721 (247)
Metabolites, 2020 Glycomics measurements, like all other high-throughput technologies, are subject to technical variation due to fluctuations in the experimental conditions. The removal of this non-biological signal from the data is referred to as normalization.
Elisa Benedetti +16 more
doaj +1 more source
mBio, 2023 Malaria is a leading cause of illness and death in children under 5 years of age in Sub-Saharan Africa. Currently, there is no highly efficacious malaria vaccine capable of inducing long-lasting immunity.
Winter A. Okoth +11 more
doaj +1 more source
Protein glycosylation as a diagnostic and prognostic marker of chronic inflammatory gastrointestinal and liver diseases [PDF]
, 2020 Glycans are sequences of carbohydrates that are added to proteins or lipids to modulate their structure and function. Glycans modify proteins required for regulation of immune cells, and alterations have been associated with inflammatory conditions.
Callewaert, Nico +6 more
core +1 more source
Microbiology Spectrum, 2023 Escherichia coli signal peptidase I (LepB) has been shown to inefficiently cleave secreted proteins with aromatic amino acids at the second position after the signal peptidase cleavage site (P2′).
Joanna E. Musik +8 more
doaj +1 more source
Cell surface-specific N-glycan profiling in breast cancer [PDF]
, 2013 Aberrant changes in specific glycans have been shown to be associated with immunosurveillance, tumorigenesis, tumor progression and metastasis. In this study, the N-glycan profiling of membrane proteins from human breast cancer cell lines and tissues was
Chen, Cuiying +8 more
core +15 more sources
Shotgun glycomics: a microarray strategy for functional glycomics [PDF]
Nature Methods, 2010 Major challenges of glycomics are to characterize a glycome and identify functional glycans as ligands for glycan-binding proteins (GBPs). To address these issues we developed a general strategy termed shotgun glycomics. We focus on glycosphingolipids (GSLs), a class of glycoconjugates that is challenging to study, recognized by toxins, antibodies and ...
Song, Xuezheng +9 more
openaire +2 more sources
Journal of Dairy Science, 2008 Bovine milk oligosaccharides have several potentially important biological activities including the prevention of pathogen binding to the intestinal epithelial and as nutrients for beneficial bacteria. It has been suggested that milk oligosaccharides are an important source of complex carbohydrates as supplements for the food and the pharmaceutical ...
N, Tao +5 more
openaire +2 more sources
Cellular O-Glycome Reporter/Amplification to explore O-glycans of living cells [PDF]
, 2015 Protein O-glycosylation has key roles in many biological processes, but the repertoire of O-glycans synthesized by cells is difficult to determine. Here we describe an approach termed Cellular O-Glycome Reporter/Amplification (CORA), a sensitive method ...
Antonopoulos, A +9 more
core +1 more source
Proceedings of the National Academy of Sciences, 2009 Molecular imaging enables visualization of specific molecules in vivo and without substantial perturbation to the target molecule's environment. Glycans are appealing targets for molecular imaging but are inaccessible with conventional approaches.
Scott T, Laughlin, Carolyn R, Bertozzi
openaire +2 more sources