Results 31 to 40 of about 16,721 (247)
Bioinformatics Approach for Functional Glycomics [PDF]
, 2007 Presentation in the Human Glycomics Proteomics Disease Initiative (HGPI ...
James C. Paulson
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BMC Medicine, 2018 Background The continuing morbidity and mortality associated with infection with malaria parasites highlights the urgent need for a vaccine. The efficacy of sub-unit vaccines tested in clinical trials in malaria-endemic areas has thus far been ...
Danielle I. Stanisic +14 more
doaj +1 more source
A novel mechanism for binding of galactose-terminated glycans by the C-type carbohydrate recognition domain in blood dendritic cell antigen 2 [PDF]
, 2015 Blood dendritic cell antigen 2 (BDCA-2; also designated CLEC4C or CD303) is uniquely expressed on plasmacytoid dendritic cells. Stimulation of BDCA-2 with antibodies leads to an anti-inflammatory response in these cells, but the natural ligands for the ...
Drickamer, K +5 more
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The Capricious Nature of Bacterial Pathogens: Phasevarions and Vaccine Development
Frontiers in Immunology, 2016 Infectious diseases are a leading cause of morbidity and mortality worldwide, and vaccines are one of the most successful and cost-effective tools for disease prevention.
Aimee Tan +3 more
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Characterization of Cell Glycocalyx with Mass Spectrometry Methods. [PDF]
, 2019 The cell membrane plays an important role in protecting the cell from its extracellular environment. As such, extensive work has been devoted to studying its structure and function.
Lebrilla, Carlito B +3 more
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Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides [PDF]
, 2020 Despite evident regulatory roles of heparan sulfate (HS) saccharides in numerous biological processes, definitive information on the bioactive sequences of these polymers is lacking, with only a handful of natural structures sequenced to date.
Grabarics, Márkó +9 more
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Mapping the complete glycoproteome of virion-derived HIV-1 gp120 provides insights into broadly neutralizing antibody binding [PDF]
, 2016 The surface envelope glycoprotein (SU) of Human immunodeficiency virus type 1 (HIV-1), gp120SU plays an essential role in virus binding to target CD4+ T-cells and is a major vaccine target.
Bess, JW +15 more
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Pneumococcal Phasevarions Control Multiple Virulence Traits, Including Vaccine Candidate Expression
Microbiology Spectrum, 2022 Streptococcus pneumoniae is the most common cause of bacterial illness worldwide. Current vaccines based on the polysaccharide capsule are only effective against a limited number of the >100 capsular serotypes.
Zachary N. Phillips +12 more
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A structural and functional model for human bone sialoprotein [PDF]
, 2012 Human bone sialoprotein (BSP) is an essential component of the extracellular matrix of bone. It is thought to be the primary nucleator of hydroxyapatite crystallization, and is known to bind to hydroxyapatite, collagen, and cells.
Durrant, Marcus, Vincent, Kevin
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